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Query: HECTD3

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
HECTD3 0 -1.006 -0.230 0.290 -0.803

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
HECTD3 Ubiquitylation K322 -0.493 _RVVVYGGEGDNLKK(gl)_

Background Information for HECTD3:


Pubmed-HECTD3 »
Uniprot-HECTD3 »
Biogrid-HECTD3 »
ProteomicsDB-HECTD3 »

Tumorportal-HECTD3 »
COSMIC-HECTD3 »
GenomeRNAi-HECTD3 »
Genecards-HECTD3


Protein-protein Interactions for HECTD3
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ANGPT2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CCDC130 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CHRDL1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CLEC3A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait COPS7B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CPA6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait EGFL6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FOSL2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GAS2L1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GAST Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HECTD3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LYZL1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LYZL2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MRM1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MRPS24 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MRPS34 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NKAP Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PARD6B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait POGLUT1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PTRF Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RBFA Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RG9MTD1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RSPO1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SCCPDH Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SERPINA5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TTC25 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait WFDC10A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait WNT9B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZBBX Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNF317 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in HECTD3
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members HECT IPR000569 0.04
Category members APC_su10/DOC_dom IPR004939 0
Category members Galactose-bd-like IPR008979 0


Protein complexes (CORUM database) featuring HECTD3
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring HECTD3
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members Pathway Pathway_621 REACTOME_ADAPTIVE_IMMUNE_SYSTEM 0 4.72
Category members Pathway Pathway_458 REACTOME_IMMUNE_SYSTEM 0 3
Category members Pathway Pathway_764 REACTOME_CLASS_I_MHC_MEDIATED_ANTIGEN_PROCESSING_PRESENTATION 0 2.56
Category members Pathway Pathway_832 REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION 0 1.58
Category members GO Category GO:0048471 perinuclear region of cytoplasm Database 0.39
Category members GO Category GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process Database 0.27
Category members GO Category GO:0004842 ubiquitin-protein ligase activity Database 0.24
Category members GO Category GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process Database 0.23
Category members GO Category GO:0019905 syntaxin binding Database 0.05


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