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Query: HERC3

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
HERC3 0 2.610 -1.630 2.450

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
HERC3 Ubiquitylation K870 0.160 _ESYGVIEQK(gl)K_

Background Information for HERC3:


Pubmed-HERC3 »
Uniprot-HERC3 »
Biogrid-HERC3 »
ProteomicsDB-HERC3 »

Tumorportal-HERC3 »
COSMIC-HERC3 »
GenomeRNAi-HERC3 »
Genecards-HERC3


Protein-protein Interactions for HERC3
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ACOX3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CYP39A1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CYP8B1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FAM189B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HERC3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HSD17B3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait IL17RC Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait KCNC4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait POTEC Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SLC25A2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TTLL2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in HERC3
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members RCC1/BLIP-II IPR009091 0.24
Category members Reg_chr_condens IPR000408 0.23
Category members HECT IPR000569 0.04


Protein complexes (CORUM database) featuring HERC3
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring HERC3
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members Pathway Pathway_888 KEGG_UBIQUITIN_MEDIATED_PROTEOLYSIS 0 2.22
Category members GO Category GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process Database 0.27
Category members GO Category GO:0004842 ubiquitin-protein ligase activity Database 0.24
Category members GO Category GO:0016023 cytoplasmic membrane-bounded vesicle Database 0.17


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