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Query: HECW2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
HECW2 0 0.649 0.150 0.240

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
HECW2 Phosphorylation S48 0.133 0.276 _ANS(ph)DTDLVTSESR_

Background Information for HECW2:


Pubmed-HECW2 »
Uniprot-HECW2 »
Biogrid-HECW2 »
ProteomicsDB-HECW2 »

Tumorportal-HECW2 »
COSMIC-HECW2 »
GenomeRNAi-HECW2 »
Genecards-HECW2


Protein-protein Interactions for HECW2
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ARRDC1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ARRDC3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C18orf1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FAM189A2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FAM189B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LITAF Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SPG20 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TMEM51 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait WBP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in HECW2
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members WW_dom IPR001202 1.15
Category members HECT IPR000569 0.04
Category members C2_dom IPR000008 0


Protein complexes (CORUM database) featuring HECW2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring HECW2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members DDR Literature pubmedid:19647519 Paulsen et al., 2009 siRNA screen for g-H2A.x phosphorylation 3.6
Category members GO Category GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process Database 0.27
Category members GO Category GO:0004842 ubiquitin-protein ligase activity Database 0.24


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