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Query: TRIP12

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
TRIP12 2 7.267 -1.630 2.710 -0.585 -0.217
TRIP12 2 7.267 -1.630 2.710 0.578 0.523

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
TRIP12 Ubiquitylation K1049 0.143 0.864 _LSDVLK(gl)R_
TRIP12 Phosphorylation S1064 0.034 -0.036 _YS(ph)PPRDDDKVDNQAK_
TRIP12 Ubiquitylation K1473 -0.085 _AQTAPTK(gl)TSPR_
TRIP12 Ubiquitylation K1709 -0.044 -0.188 _GEEVTLSNPK(gl)GSQEGTK_
TRIP12 Phosphorylation S1039 -1.279 -0.356 _DDSLDLS(ph)PQGR_
TRIP12 Phosphorylation S354 -0.672 -0.510 _RSES(ph)PPAELPSLR_
TRIP12 Phosphorylation S990 -1.351 _HLAESESLLTS(ph)PPK_
TRIP12 Ubiquitylation K1086 -1.660 -1.398 _SPTTTQSPK(gl)SSFLASLNPK_
TRIP12 Ubiquitylation K1096 2.593 _SSFLASLNPK(gl)TWGR_

Background Information for TRIP12:





Protein-protein Interactions for TRIP12

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait EXOSC9 Cat. description Hein, Mann, Cell 2015
Category members IP bait FAM46A Cat. description Hein, Mann, Cell 2015
Category members IP bait HNRNPF Cat. description Hein, Mann, Cell 2015
Category members IP bait KIF20A Cat. description Hein, Mann, Cell 2015
Category members IP bait KTN1 Cat. description Hein, Mann, Cell 2015
Category members IP bait PHF8 Cat. description Hein, Mann, Cell 2015
Category members IP bait TUBGCP5 Cat. description Hein, Mann, Cell 2015
Category members IP bait VHL Cat. description Hein, Mann, Cell 2015
Category members IP bait BCAT1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CAPN1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait EIF3I Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait KBTBD7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MECP2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait OPCML Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RP2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in TRIP12

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members ARM-type_fold IPR016024 9.26
Category members HECT IPR000569 0.04
Category members WWE-dom IPR004170 0
Category members WWE-dom_subgr IPR018123 0


Protein complexes (CORUM database) featuring TRIP12

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring TRIP12

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members DDR Literature pubmedid:24332808 Marechal et al., 2014 RPA-mediated recruitment INF
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005654 nucleoplasm Database INF
Category members GO Category GO:0006281 DNA repair Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0005488 binding Database 9.32
Category members Pathway Pathway_621 REACTOME_ADAPTIVE_IMMUNE_SYSTEM 0 4.72
Category members GO Category GO:0006974 cellular response to DNA damage stimulus Database 3.57
Category members Pathway Pathway_458 REACTOME_IMMUNE_SYSTEM 0 3
Category members Pathway Pathway_764 REACTOME_CLASS_I_MHC_MEDIATED_ANTIGEN_PROCESSING_PRESENTATION 0 2.56
Category members Pathway Pathway_888 KEGG_UBIQUITIN_MEDIATED_PROTEOLYSIS 0 2.22
Category members Pathway Pathway_832 REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION 0 1.58
Category members GO Category GO:0008270 zinc ion binding Database 0.29
Category members GO Category GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process Database 0.27
Category members GO Category GO:0004842 ubiquitin-protein ligase activity Database 0.24
Category members GO Category GO:0016567 protein ubiquitination Database 0.07
Category members GO Category GO:0046966 thyroid hormone receptor binding Database 0
Category members GO Category GO:0009790 embryo development Database 0


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