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WWE-dom
(IPR004170)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
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Protein Results:

 Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
HUWE1 3 -1.250 1.500
HUWE1 3 -1.250 1.500 -0.684 0.362 -0.152
TRIP12 2 -1.630 2.710 -0.585 -0.217
TRIP12 2 -1.630 2.710 0.578 0.523
PARP12 0 -0.390 0.060
PARP12 0 -0.390 0.060 -0.228 -0.608 -0.294 -0.298 0.086
ZC3HAV1 0 0.080 -0.160 -0.228 -0.608 -0.294 -0.298 0.086
ZC3HAV1 0 0.080 -0.160

PTM Sites:

 Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
HUWE1 Ubiquitylation K27 -1.058 _ALIDKLK(gl)_
HUWE1 Phosphorylation S131 0.155 _IQRPNTTQEGEEMETDMDVADVAMESS(ph)PGSSISMEHR_
HUWE1 Ubiquitylation K324 1.996 _QLMEIK(gl)AASLR_
HUWE1 Ubiquitylation K516 1.194 _SMLNFLK(gl)K_
HUWE1 Ubiquitylation K517 1.194 _SMLNFLK(gl)K_
HUWE1 Phosphorylation S648 0.066 _RS(ph)SDPLGDTASNLGSAVDELMR_
HUWE1 Phosphorylation S649 0.305 _RSS(ph)DPLGDTASNLGSAVDELMR_
HUWE1 Ubiquitylation K674 -0.756 0.052 _HQPTLK(gl)TDATTAIIK_
HUWE1 Ubiquitylation K701 -0.689 0.009 _YICQK(gl)PSIQK_
HUWE1 Ubiquitylation K1037 -0.044 _SK(gl)ITPAMAAR_
HUWE1 Ubiquitylation K1107 0.382 0.570 _STASALTK(gl)LLTK_
HUWE1 Ubiquitylation K1111 -2.104 _LLTK(gl)GLSWQPPPYTPTPR_
HUWE1 Phosphorylation S1368 2.745 2.124 _DLS(ph)MSEEDQM(ox)M(ox)R_
HUWE1 Phosphorylation S1395 0.200 0.293 _AES(ph)PEEVACRK_
HUWE1 Ubiquitylation K1470 0.459 0.499 _VCDLIMTAIK(gl)R_
HUWE1 Ubiquitylation K1608 0.575 -0.055 _AQMTK(gl)YLQSNSNNWR_
HUWE1 Ubiquitylation K1708 -0.283 _TLEESK(gl)EMDIK_
HUWE1 Ubiquitylation K1713 0.810 _TLEESKEMDIK(gl)R_
HUWE1 Phosphorylation T1722 1.903 0.188 _GNDT(ph)PLALESTNTEK_
HUWE1 Ubiquitylation K1840 0.879 0.090 _HTMEK(gl)VVR_
HUWE1 Phosphorylation S1903 0.533 0.300 _GS(ph)GTASDDEFENLR_
HUWE1 Phosphorylation T1905 0.542 0.300 _GSGT(ph)ASDDEFENLR_
HUWE1 Phosphorylation S1907 0.685 0.593 _GSGTAS(ph)DDEFENLR_
HUWE1 Ubiquitylation K1917 -1.189 -0.700 _IK(gl)GPNAVQLVK_
HUWE1 Ubiquitylation K2172 0.867 -0.078 _ALAMAESTEK(gl)HAR_
HUWE1 Ubiquitylation K2219 -0.368 0.472 _K(gl)GLVNDLAR_
HUWE1 Ubiquitylation K2267 -0.095 -0.110 _IVNQPSSLFGSK(gl)SASSK_
HUWE1 Phosphorylation S2362 0.398 0.411 _DGGS(ph)GNSTIIVSR_
HUWE1 Phosphorylation S2372 0.517 _S(ph)GEDESQEDVLMDEAPSNLSQASTLQANR_
HUWE1 Phosphorylation S2377 0.768 _SGEDES(ph)QEDVLMDEAPSNLSQASTLQANR_
HUWE1 Phosphorylation S2532 0.684 _HADHSSLTLGS(ph)GSSTTR_
HUWE1 Ubiquitylation K2703 -0.653 _QLAEEETK(gl)ITDK_
HUWE1 Phosphorylation S2887 -0.764 -0.940 _AGS(ph)STPGDAPPAVAEVQGR_
HUWE1 Phosphorylation T2889 1.022 0.924 _AGSST(ph)PGDAPPAVAEVQGR_
HUWE1 Phosphorylation S2917 -1.340 _SDGSGESAQPPEDS(ph)SPPASSESSSTR_
HUWE1 Phosphorylation S2918 -1.072 -1.081 _SDGSGESAQPPEDSS(ph)PPASSESSSTR_
HUWE1 Ubiquitylation K3244 -0.067 _SSESELCIETPK(gl)LTTSEEK_
HUWE1 Ubiquitylation K3345 0.581 0.528 _HVLDTLIQLAK(gl)_
HUWE1 Phosphorylation S3373 0.040 0.333 _ACS(ph)PCSSQSSSSGICTDFWDLLVK_
HUWE1 Ubiquitylation K3452 0.345 0.352 _SSLLTEK(gl)LLR_
HUWE1 Ubiquitylation K3558 -0.045 -0.283 _SPAK(gl)VSDGGSSSTDFK_
HUWE1 Ubiquitylation K3621 -0.956 _DTVLK(gl)LLLNGAR_
HUWE1 Phosphorylation S3662 0.940 0.734 _AQCETLS(ph)PDGLPEEQPQTTK_
HUWE1 Ubiquitylation K3677 -1.251 -1.639 _AQCETLSPDGLPEEQPQTTKLK(gl)_
HUWE1 Ubiquitylation K3716 -0.483 _ELQLPSMSMLTSK(gl)TSTQK_
HUWE1 Phosphorylation S3752 0.910 0.498 _LGS(ph)SGLGSASSIQAAVR_
HUWE1 Phosphorylation S3753 1.473 0.728 _LGSS(ph)GLGSASSIQAAVR_
HUWE1 Phosphorylation S3757 0.931 0.989 _LGSSGLGS(ph)ASSIQAAVR_
HUWE1 Phosphorylation S3816 -0.580 -0.661 _REESPMDVDQPS(ph)PSAQDTQSIASDGTPQGEK_
HUWE1 Phosphorylation S3906 -1.731 -2.374 _ES(ph)QLAHIKDEPPPLSPAPLTPATPSSLDPFFSR_
HUWE1 Phosphorylation S3919 -1.085 -1.773 _ESQLAHIKDEPPPLS(ph)PAPLTPATPSSLDPFFSR_
HUWE1 Ubiquitylation K3954 -2.295 -1.326 _EPSSMHISSSLPPDTQK(gl)FLR_
HUWE1 Ubiquitylation K3997 0.639 0.630 _VLDFDVK(gl)R_
HUWE1 Ubiquitylation K4014 0.012 _LDEGLRK(gl)EDMAVHVR_
HUWE1 Ubiquitylation K4116 0.312 _IVAK(gl)AVYDNR_
HUWE1 Ubiquitylation K4295 0.703 0.688 _AK(gl)FLQFVTGTSK_
PARP12 Phosphorylation S263 -0.035 0.554 _DSSGSVS(ph)PNTLSQEEGDQICLYHIR_
TRIP12 Phosphorylation S354 -0.672 -0.510 _RSES(ph)PPAELPSLR_
TRIP12 Phosphorylation S990 -1.351 _HLAESESLLTS(ph)PPK_
TRIP12 Phosphorylation S1039 -1.279 -0.356 _DDSLDLS(ph)PQGR_
TRIP12 Ubiquitylation K1049 0.143 0.864 _LSDVLK(gl)R_
TRIP12 Phosphorylation S1064 0.034 -0.036 _YS(ph)PPRDDDKVDNQAK_
TRIP12 Ubiquitylation K1086 -1.660 -1.398 _SPTTTQSPK(gl)SSFLASLNPK_
TRIP12 Ubiquitylation K1096 2.593 _SSFLASLNPK(gl)TWGR_
TRIP12 Ubiquitylation K1473 -0.085 _AQTAPTK(gl)TSPR_
TRIP12 Ubiquitylation K1709 -0.044 -0.188 _GEEVTLSNPK(gl)GSQEGTK_
ZC3HAV1 Phosphorylation S275 0.409 0.461 _SCTPS(ph)PDQISHR_
ZC3HAV1 Phosphorylation S284 0.511 0.451 _AS(ph)LEDAPVDDLTR_
ZC3HAV1 Phosphorylation S302 1.342 _KFTYLGS(ph)QDR_
ZC3HAV1 Ubiquitylation K374 -1.233 _RK(gl)TVFSPTLPAAR_
ZC3HAV1 Phosphorylation S378 -0.240 0.105 _TVFS(ph)PTLPAAR_
ZC3HAV1 Phosphorylation S386 -0.801 0.173 _S(ph)SLGSLQTPEAVTTR_
ZC3HAV1 Phosphorylation S387 -0.905 0.173 _SS(ph)LGSLQTPEAVTTR_
ZC3HAV1 Ubiquitylation K448 0.090 _SLNYK(gl)STSSGHR_


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