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Query: ZC3HAV1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
ZC3HAV1 0 0.601 0.080 -0.160
ZC3HAV1 0 0.601 0.080 -0.160 -0.228 -0.608 -0.294 -0.298 0.086

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
ZC3HAV1 Phosphorylation S302 1.342 _KFTYLGS(ph)QDR_
ZC3HAV1 Phosphorylation S275 0.409 0.461 _SCTPS(ph)PDQISHR_
ZC3HAV1 Phosphorylation S284 0.511 0.451 _AS(ph)LEDAPVDDLTR_
ZC3HAV1 Phosphorylation S386 -0.801 0.173 _S(ph)SLGSLQTPEAVTTR_
ZC3HAV1 Phosphorylation S387 -0.905 0.173 _SS(ph)LGSLQTPEAVTTR_
ZC3HAV1 Phosphorylation S378 -0.240 0.105 _TVFS(ph)PTLPAAR_
ZC3HAV1 Ubiquitylation K374 -1.233 _RK(gl)TVFSPTLPAAR_
ZC3HAV1 Ubiquitylation K448 0.090 _SLNYK(gl)STSSGHR_

Background Information for ZC3HAV1:


Pubmed-ZC3HAV1 »
Uniprot-ZC3HAV1 »
Biogrid-ZC3HAV1 »
ProteomicsDB-ZC3HAV1 »

Tumorportal-ZC3HAV1 »
COSMIC-ZC3HAV1 »
GenomeRNAi-ZC3HAV1 »
Genecards-ZC3HAV1


Protein-protein Interactions for ZC3HAV1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CBX8 Cat. description Hein, Mann, Cell 2015
Category members IP bait KLC3 Cat. description Hein, Mann, Cell 2015
Category members IP bait LDHD Cat. description Hein, Mann, Cell 2015
Category members IP bait PABPC1 Cat. description Hein, Mann, Cell 2015
Category members IP bait RPL35 Cat. description Hein, Mann, Cell 2015
Category members IP bait SORT1 Cat. description Hein, Mann, Cell 2015
Category members IP bait CNBP Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DGCR8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GLTSCR2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GPATCH4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait H2AFX Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HIST1H1A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HIST1H1T Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait KIAA0020 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MAK16 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MKI67IP Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NOL12 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NSA2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NXF2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RBM34 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RPL10A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RPL13 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RPL18 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RPL18A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RPL30 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RPL37A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RPL7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RPL8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RPS8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RRS1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait STAU1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait WDR46 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZBTB48 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZC3HAV1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZCRB1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNF2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in ZC3HAV1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members WWE-dom IPR004170 0
Category members Poly(ADP-ribose)pol_cat_dom IPR012317 0


Protein complexes (CORUM database) featuring ZC3HAV1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 744 Exon junction complex (EIF4A3-MLN51-MAGOH-Y14) Database 0


Categories featuring ZC3HAV1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0003723 RNA binding Database INF
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0032481 positive regulation of type I interferon production Database 0.54
Category members GO Category GO:0005794 Golgi apparatus Database 0.27
Category members GO Category GO:0051607 defense response to virus Database 0.07
Category members GO Category GO:0045087 innate immune response Database 0.05
Category members GO Category GO:0003950 NAD+ ADP-ribosyltransferase activity Database 0
Category members GO Category GO:0009615 response to virus Database 0
Category members GO Category GO:0032727 positive regulation of interferon-alpha production Database 0
Category members GO Category GO:0032728 positive regulation of interferon-beta production Database 0
Category members GO Category GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling Database 0
Category members GO Category GO:0045071 negative regulation of viral genome replication Database 0
Category members GO Category GO:0046872 metal ion binding Database 0
Category members GO Category GO:0061014 positive regulation of mRNA catabolic process Database 0
Category members GO Category GO:0071360 cellular response to exogenous dsRNA Database 0


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