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Query: UBE3C

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
UBE3C 0 0.347 1.470 -0.710 -0.022 -0.743

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
UBE3C Ubiquitylation K145 0.477 0.635 _LTCLFQIK(gl)R_
UBE3C Ubiquitylation K907 -0.162 _FGGK(gl)DIPVTSANR_
UBE3C Ubiquitylation K63 -0.566 _K(gl)QQYSIQR_
UBE3C Ubiquitylation K565 -1.058 _LAYPETK(gl)PEVR_

Background Information for UBE3C:


Pubmed-UBE3C »
Uniprot-UBE3C »
Biogrid-UBE3C »
ProteomicsDB-UBE3C »

Tumorportal-UBE3C »
COSMIC-UBE3C »
GenomeRNAi-UBE3C »
Genecards-UBE3C


Protein-protein Interactions for UBE3C
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait KIAA1467 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SCN2B Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in UBE3C
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members HECT IPR000569 0.04
Category members IQ_motif_EF-hand-BS IPR000048 0
Category members DHFR-like_dom IPR024072 0


Protein complexes (CORUM database) featuring UBE3C
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring UBE3C
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members Pathway Pathway_621 REACTOME_ADAPTIVE_IMMUNE_SYSTEM 0 4.72
Category members GO Category GO:0000502 proteasome complex Database 3.17
Category members Pathway Pathway_458 REACTOME_IMMUNE_SYSTEM 0 3
Category members Pathway Pathway_764 REACTOME_CLASS_I_MHC_MEDIATED_ANTIGEN_PROCESSING_PRESENTATION 0 2.56
Category members GO Category GO:0000209 protein polyubiquitination Database 2.46
Category members Pathway Pathway_888 KEGG_UBIQUITIN_MEDIATED_PROTEOLYSIS 0 2.22
Category members Pathway Pathway_832 REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION 0 1.58
Category members GO Category GO:0005622 intracellular Database 0.32
Category members GO Category GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process Database 0.27
Category members GO Category GO:0004842 ubiquitin-protein ligase activity Database 0.24


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