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Query: WWP1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
WWP1 1 3.272 -1.400 1.340
WWP1 1 3.272 -1.400 1.340 -0.346 0.023 0.613
WWP1 1 3.272 0.850 -1.030
WWP1 1 3.272 0.850 -1.030 -0.346 0.023 0.613

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
WWP1 Ubiquitylation K513 -0.564 1.593 _TGK(gl)SALDNGPQIAYVR_
WWP1 Ubiquitylation K536 -1.895 1.126 _SSVTK(gl)GGPQIAYER_
WWP1 Ubiquitylation K861 -0.810 0.596 _VGK(gl)ENWLPR_
WWP1 Ubiquitylation K328 -0.364 0.487 _SSSAFEAAK(gl)SR_
WWP1 Ubiquitylation K350 0.049 0.396 _VYYVDHVEK(gl)R_
WWP1 Ubiquitylation K446 -1.514 -1.539 _EFDPLGPLPPGWEK(gl)R_
WWP1 Ubiquitylation K66 -0.890 _WK(gl)QPLTVIVTPVSK_
WWP1 Ubiquitylation K478 -1.265 _SQGQLNEK(gl)PLPEGWEMR_

Background Information for WWP1:


Pubmed-WWP1 »
Uniprot-WWP1 »
Biogrid-WWP1 »
ProteomicsDB-WWP1 »

Tumorportal-WWP1 »
COSMIC-WWP1 »
GenomeRNAi-WWP1 »
Genecards-WWP1


Protein-protein Interactions for WWP1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait BCAS2 Cat. description Hein, Mann, Cell 2015
Category members IP bait CDK8 Cat. description Hein, Mann, Cell 2015
Category members IP bait MTX1 Cat. description Hein, Mann, Cell 2015
Category members IP bait SETD4 Cat. description Hein, Mann, Cell 2015
Category members IP bait SMAD3 Cat. description Hein, Mann, Cell 2015
Category members IP bait XRCC5 Cat. description Hein, Mann, Cell 2015
Category members IP bait ARRDC1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ARRDC3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C18orf1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CPSF6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FAM189A2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FAM189B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FAM70A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FAM70B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ILDR1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SPG20 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TMEM51 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TMEM66 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TNFRSF19 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TXNIP Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait WBP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in WWP1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members WW_dom IPR001202 1.15
Category members HECT IPR000569 0.04
Category members C2_dom IPR000008 0


Protein complexes (CORUM database) featuring WWP1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring WWP1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0019048 modulation by virus of host morphology or physiology Database 7.81
Category members Pathway Pathway_621 REACTOME_ADAPTIVE_IMMUNE_SYSTEM 0 4.72
Category members Pathway Pathway_458 REACTOME_IMMUNE_SYSTEM 0 3
Category members Pathway Pathway_764 REACTOME_CLASS_I_MHC_MEDIATED_ANTIGEN_PROCESSING_PRESENTATION 0 2.56
Category members Pathway Pathway_888 KEGG_UBIQUITIN_MEDIATED_PROTEOLYSIS 0 2.22
Category members Pathway Pathway_832 REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION 0 1.58
Category members Pathway Pathway_666 KEGG_ENDOCYTOSIS 0 1.25
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0045892 negative regulation of transcription, DNA-dependent Database 1.15
Category members Pathway Pathway_208 PID_TAP63_PATHWAY 0 0.52
Category members Pathway Pathway_933 PID_TGFBR_PATHWAY 0 0.52
Category members GO Category GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process Database 0.27
Category members GO Category GO:0000151 ubiquitin ligase complex Database 0.24
Category members GO Category GO:0004842 ubiquitin-protein ligase activity Database 0.24
Category members GO Category GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process Database 0.23
Category members GO Category GO:0055085 transmembrane transport Database 0.12
Category members GO Category GO:0016567 protein ubiquitination Database 0.07
Category members Pathway Pathway_545 REACTOME_SIGNALING_BY_ERBB4 0 0.05
Category members GO Category GO:0046718 viral entry into host cell Database 0.04
Category members Pathway Pathway_209 PID_DELTA_NP63_PATHWAY 0 0
Category members Pathway Pathway_609 PID_ERBB4_PATHWAY 0 0
Category members GO Category GO:0007165 signal transduction Database 0
Category members GO Category GO:0007417 central nervous system development Database 0
Category members GO Category GO:0034220 ion transmembrane transport Database 0


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