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PID_DELTA_NP63_PATHWAY
(Pathway_209)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
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Protein Results:

 Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
GSK3B 2 1.020 -0.870 -1.128 1.091
ADRM1 2 1.030 -0.250 -0.115
ITCH 1 1.000 -0.610 -0.346 0.023 0.613
WWP1 1 -1.400 1.340
WWP1 1 0.850 -1.030
WWP1 1 -1.400 1.340 -0.346 0.023 0.613
WWP1 1 0.850 -1.030 -0.346 0.023 0.613
TOP2A 1 -1.940 3.540
TOP2A 1 -1.940 3.540 -1.993 0.211 0.211
TCF7L1 1 -2.040 2.970 -0.741
GNB2L1 1 1.000 -0.100 0.279 1.704
GNB2L1 1 1.000 -0.100 -0.278 -0.107 -0.424
DLX6 0 0.390 -0.840
DLX6 0 0.640 -0.810
DLX6 0 0.390 -0.840 -1.286 0.204
DLX6 0 0.640 -0.810 -1.286 0.204
MRE11A 0 1.600 -0.730 0.145 0.420
MRE11A 0 1.600 -0.730 0.023 0.453 0.150
PPP2R5A 0 -0.210 0.930
FOSL2 0 0.940 -0.940
HBP1 0 -1.130 1.580
DLX5 0 -0.590 0.650 -1.286 0.204
HES1 0 -0.940 0.860
HELLS 0 -1.320 1.650 -1.393 -0.483 -0.069 -0.340 -0.345
RAB38 0 -1.070 1.480 1.011 0.091
MDM2 0 -0.210 0.080
YAP1 0 1.010 -0.370
CDKN2A 0 -0.080 -0.260 -0.556 -1.080 -3.270 -1.110
ATM 0 0.398 0.474
CCNB2 0
T 0 0.200 -0.340 -0.755
STXBP4 0 0.810 0.110
FASN 0 -0.350 -0.530 -0.550 -0.478 -0.892 -0.134 0.004
SFN 0 0.890 0.120 -4.300
ADA 0 0.340 -0.830

PTM Sites:

 Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
ADA Ubiquitylation K312 0.123 _STLDTDYQMTK(gl)R_
ADRM1 Ubiquitylation K21 -0.336 0.189 _GASNK(gl)YLVEFR_
ADRM1 Ubiquitylation K34 -0.456 -0.090 _MSLK(gl)GTTVTPDKRK_
ADRM1 Ubiquitylation K42 -0.148 -2.067 _MSLK(gl)GTTVTPDK(gl)R_
ADRM1 Ubiquitylation K97 0.835 _VYVLK(gl)FK_
ADRM1 Phosphorylation S211 2.181 _S(ph)QSAAVTPSSTTSSTR_
ADRM1 Phosphorylation S213 2.423 2.134 _SQS(ph)AAVTPSSTTSSTR_
ATM Ubiquitylation K307 -0.196 _GAYESTK(gl)WR_
ATM Ubiquitylation K331 -0.126 _GK(gl)YSSGFR_
ATM Ubiquitylation K385 -0.669 _ESSDYSVPCK(gl)R_
ATM Ubiquitylation K1101 -0.548 _LFQDTK(gl)GDSSR_
ATM Ubiquitylation K1109 -1.666 _LLK(gl)ALPLK_
ATM Ubiquitylation K1698 -1.026 _DASYTK(gl)ALK_
ATM Ubiquitylation K1738 -0.137 _SAAVTCLK(gl)NILATK_
ATM Ubiquitylation K2025 -1.497 _SIGEPDSLYGCGGGK(gl)MLQPITR_
CCNB2 Phosphorylation S92 -0.838 -0.676 _GPS(ph)PTPEDVSMKEENLCQAFSDALLCK_
DLX5 Phosphorylation S225 -0.821 _SGEIPSEQHPGAS(ph)AS(ph)PPCASPPVSAPASWDFGVPQR_
DLX5 Phosphorylation S227 -1.137 _SGEIPSEQHPGASAS(ph)PPCAS(ph)PPVSAPASWDFGVPQR_
DLX5 Phosphorylation S232 -1.137 _SGEIPSEQHPGASAS(ph)PPCAS(ph)PPVSAPASWDFGVPQR_
DLX6 Phosphorylation S130 -1.478 -1.295 _S(ph)PALPPVWDVSASAK_
DLX6 Phosphorylation S225 -0.821 _SGEIPSEQHPGAS(ph)AS(ph)PPCASPPVSAPASWDFGVPQR_
DLX6 Phosphorylation S227 -1.137 _SGEIPSEQHPGASAS(ph)PPCAS(ph)PPVSAPASWDFGVPQR_
DLX6 Phosphorylation S232 -1.137 _SGEIPSEQHPGASAS(ph)PPCAS(ph)PPVSAPASWDFGVPQR_
FASN Ubiquitylation K41 -0.859 -0.543 _WK(gl)AGLYGLPR_
FASN Phosphorylation S207 0.105 0.507 _LGMLS(ph)PEGTCK_
FASN Ubiquitylation K213 -0.346 -0.011 _LGMLSPEGTCK(gl)AFDTAGNGYCR_
FASN Ubiquitylation K235 -0.149 0.117 _SEGVVAVLLTK(gl)K_
FASN Ubiquitylation K236 -0.149 -0.024 _SEGVVAVLLTKK(gl)_
FASN Ubiquitylation K326 0.372 _QEPLLIGSTK(gl)SNM(ox)GHPEPASGLAALAK_
FASN Ubiquitylation K436 -0.250 _TPEAVQK(gl)LLEQGLR_
FASN Ubiquitylation K528 -0.086 -0.587 _SDEAVK(gl)PFGLK_
FASN Ubiquitylation K673 0.201 0.234 _K(gl)EGVFAK(gl)EVR_
FASN Ubiquitylation K776 -1.050 _GLK(gl)PSCTIIPLMK_
FASN Phosphorylation S974 -1.491 -0.989 _LFDHPES(ph)PTPNPTEPLFLAQAEVYK_
FASN Phosphorylation T976 -1.624 -1.495 _LFDHPESPT(ph)PNPTEPLFLAQAEVYK_
FASN Phosphorylation S1028 0.133 -0.404 _DNWVS(ph)FM(ox)DTMLQMSILGSAK_
FASN Ubiquitylation K1065 -1.459 _QK(gl)LYTLQDK_
FASN Ubiquitylation K1072 0.386 0.144 _LYTLQDK(gl)AQVADVVVSR_
FASN Ubiquitylation K1142 0.056 0.226 _AALQEELQLCK(gl)GLVQALQTK_
FASN Ubiquitylation K1151 0.234 -0.094 _GLVQALQTK(gl)VTQQGLK_
FASN Ubiquitylation K1158 -0.496 -0.468 _VTQQGLK(gl)MVVPGLDGAQIPRDPSQQELPR_
FASN Ubiquitylation K1239 -0.362 _ACLDTAVENMPSLK(gl)MK_
FASN Ubiquitylation K1241 -0.510 -0.579 _ACLDTAVENMPSLKMK(gl)_
FASN Phosphorylation S1411 -0.978 _RPTPQDS(ph)PIFLPVDDTSFR_
FASN Ubiquitylation K1582 -1.228 -2.032 _DIMLATGK(gl)LSPDAIPGK_
FASN Ubiquitylation K1704 -0.247 _VFTTVGSAEK(gl)R_
FASN Ubiquitylation K1847 0.204 _YMAQGK(gl)HIGK_
FASN Ubiquitylation K1866 -1.615 -1.050 _VVVQVLAEEPEAVLK(gl)GAKPK_
FASN Ubiquitylation K1869 -0.967 _VVVQVLAEEPEAVLKGAK(gl)_
FASN Ubiquitylation K1871 -0.926 _GAK(gl)PKLM(ox)SAISK_
FASN Ubiquitylation K1878 0.194 -0.638 _LM(ox)SAISK(gl)TFCPAHK_
FASN Ubiquitylation K1911 -0.329 0.084 _GVQK(gl)LVLTSR_
FASN Ubiquitylation K1927 -0.254 -0.492 _TGYQAK(gl)QVR_
FASN Ubiquitylation K1993 -1.641 _DGLLENQTPEFFQDVCK(gl)PK_
FASN Phosphorylation S2198 -1.105 -1.296 _ADEAS(ph)ELACPT(ph)PK_
FASN Phosphorylation T2204 -0.587 -0.205 _ADEASELACPT(ph)PKEDGLAQQQTQLNLR_
FASN Ubiquitylation K2391 -0.844 -0.267 _VLEALLPLK(gl)GLEER_
FASN Ubiquitylation K2426 -0.591 0.390 _SFYYK(gl)LR_
FASN Ubiquitylation K2438 -0.623 -0.362 _AK(gl)YHGNVM(ox)LLR_
FASN Ubiquitylation K2449 -0.636 0.411 _AK(gl)TGGAYGEDLGADYNLSQVCDGK_
FOSL2 Phosphorylation S200 -0.517 _S(ph)PPAPGLQPMR_
GNB2L1 Ubiquitylation K38 -0.238 0.350 _DK(gl)TIIMWK_
GNB2L1 Ubiquitylation K106 -0.290 _RFVGHTK(gl)DVLSVAFSSDNR_
GNB2L1 Ubiquitylation K130 0.632 _TIK(gl)LWNTLGVCK_
GNB2L1 Ubiquitylation K175 -0.554 -0.015 _LVK(gl)VWNLANCK_
GNB2L1 Ubiquitylation K183 -0.161 -0.282 _VWNLANCK(gl)_
GNB2L1 Ubiquitylation K185 -0.061 -0.249 _VWNLANCKLK(gl)_
GNB2L1 Ubiquitylation K257 -0.288 _YWLCAATGPSIK(gl)_
GNB2L1 Ubiquitylation K271 0.756 -0.007 _IIVDELK(gl)QEVISTSSK_
GSK3B Phosphorylation S9 -0.483 0.010 _TTS(ph)FAESCKPVQQPSAFGSMK_
GSK3B Ubiquitylation K85 -0.204 _LCDSGELVAIK(gl)K_
GSK3B Ubiquitylation K86 -0.204 _LCDSGELVAIK(gl)K_
GSK3B Phosphorylation S215 0.296 0.477 _GEPNVS(ph)YICSR_
GSK3B Phosphorylation Y216 0.356 0.376 _GEPNVSY(ph)ICSR_
GSK3B Phosphorylation T390 2.800 2.527 _IQAAAST(ph)PTNATAASDANTGDR_
HBP1 Ubiquitylation K426 -1.246 _NCGSPGSSQLSSNSLYAK(gl)AVK_
HELLS Ubiquitylation K74 0.655 _LQHLLEK(gl)SNIYSK_
HELLS Phosphorylation S115 0.257 _NS(ph)IDASEEKPVMR_
HELLS Ubiquitylation K474 -0.723 _EVVVYAPLSK(gl)K_
HELLS Ubiquitylation K475 -0.723 _EVVVYAPLSK(gl)K_
HELLS Ubiquitylation K753 0.741 _NHFK(gl)GGQSGLNLSK_
HELLS Ubiquitylation K776 0.359 _ELMELLK(gl)SR_
HES1 Ubiquitylation K66 0.212 _TLILDALK(gl)K_
HES1 Ubiquitylation K67 0.212 _TLILDALK(gl)K_
HES1 Ubiquitylation K109 -0.891 _AQMTAALSTDPSVLGK(gl)YR_
ITCH Ubiquitylation K66 -0.890 _WK(gl)QPLTVIVTPVSK_
ITCH Ubiquitylation K350 0.049 0.396 _VYYVDHVEK(gl)R_
ITCH Ubiquitylation K446 -1.514 -1.539 _EFDPLGPLPPGWEK(gl)R_
ITCH Ubiquitylation K478 -1.265 _SQGQLNEK(gl)PLPEGWEMR_
ITCH Ubiquitylation K513 -0.564 1.593 _TGK(gl)SALDNGPQIAYVR_
ITCH Ubiquitylation K861 -0.810 0.596 _VGK(gl)ENWLPR_
MDM2 Phosphorylation S166 0.576 1.068 _AIS(ph)ETEENSDELSGER_
MDM2 Ubiquitylation K334 -0.872 _ENWLPEDK(gl)GK_
MDM2 Ubiquitylation K336 -0.872 _ENWLPEDK(gl)GK_
MDM2 Ubiquitylation K363 0.883 _LENSTQAEEGFDVPDCK(gl)K_
MDM2 Ubiquitylation K364 0.883 _LENSTQAEEGFDVPDCK(gl)K_
MDM2 Ubiquitylation K473 0.806 _NK(gl)PCPVCR_
MRE11A Ubiquitylation K387 0.442 _FSQK(gl)FVDR_
PPP2R5A Phosphorylation S5 -0.414 _(ac)SSSS(ph)PPAGAASAAISASEK_
RAB38 Ubiquitylation K20 -1.240 _VLVVGDAAVGK(gl)TSLVQR_
SFN Ubiquitylation K11 0.561 0.388 _AK(gl)LAEQAER_
SFN Ubiquitylation K49 -0.093 0.337 _NLLSVAYK(gl)_
STXBP4 Phosphorylation S6 0.972 _(ac)MNKNTS(ph)TVVSPS(ph)LLEK_
STXBP4 Ubiquitylation K487 -0.179 _ELVK(gl)SVR_
TCF7L1 Ubiquitylation K88 -0.867 -0.222 _ESLEEAAK(gl)R_
TOP2A Phosphorylation S4 -0.623 -0.424 _(ac)M(ox)EVS(ph)PLQPVNENM(ox)QVNK_
TOP2A Ubiquitylation K17 -0.250 _(ac)MEVSPLQPVNENMQVNK(gl)IKK_
TOP2A Ubiquitylation K96 0.284 _IFDEILVNAADNK(gl)QR_
TOP2A Ubiquitylation K131 0.553 -0.638 _GIPVVEHK(gl)VEK_
TOP2A Ubiquitylation K386 -2.203 _ENMTLQPK(gl)SFGSTCQLSEK_
TOP2A Ubiquitylation K397 0.214 0.360 _SFGSTCQLSEK(gl)FIK_
TOP2A Ubiquitylation K426 -0.502 _AQVQLNKK(gl)_
TOP2A Ubiquitylation K489 -0.029 0.171 _GK(gl)ILNVR_
TOP2A Ubiquitylation K520 -0.260 _IVGLQYKK(gl)_
TOP2A Ubiquitylation K529 0.862 0.065 _NYEDEDSLK(gl)TLR_
TOP2A Ubiquitylation K614 -0.287 _YYK(gl)GLGTSTSK_
TOP2A Ubiquitylation K622 -0.581 _GLGTSTSK(gl)EAK_
TOP2A Ubiquitylation K632 -0.171 -0.248 _EYFADMK(gl)R_
TOP2A Ubiquitylation K655 -0.091 -0.407 _YSGPEDDAAISLAFSK(gl)K_
TOP2A Ubiquitylation K656 -0.091 -0.441 _YSGPEDDAAISLAFSKK(gl)_
TOP2A Ubiquitylation K723 -1.207 _SIPSMVDGLK(gl)PGQR_
TOP2A Ubiquitylation K1088 0.061 _GYDSDPVK(gl)AWK_
TOP2A Phosphorylation S1142 0.072 0.040 _VPDEEENEES(ph)DNEKETEK_
TOP2A Ubiquitylation K1159 -0.411 -0.659 _EQELDTLK(gl)R_
TOP2A Ubiquitylation K1199 -0.674 -1.759 _EKQDEQVGLPGKGGK(gl)_
TOP2A Phosphorylation S1249 -0.907 -0.546 _TQMAEVLPS(ph)PR_
TOP2A Phosphorylation S1283 0.168 0.028 _NENTEGS(ph)PQEDGVELEGLK_
TOP2A Phosphorylation S1411 0.232 -0.105 _S(ph)VVSDLEADDVK_
TOP2A Phosphorylation S1414 0.884 0.877 _SVVS(ph)DLEADDVK_
TOP2A Phosphorylation S1429 -1.415 -2.977 _GSVPLSS(ph)SPPATHFPDETEITNPVPK_
TOP2A Phosphorylation S1430 -1.317 _GSVPLSSS(ph)PPATHFPDETEITNPVPK_
TOP2A Phosphorylation T1434 -1.348 _GSVPLSSSPPAT(ph)HFPDETEITNPVPK_
TOP2A Phosphorylation S1506 -0.384 _RKPS(ph)TSDDSDSNFEK_
WWP1 Ubiquitylation K66 -0.890 _WK(gl)QPLTVIVTPVSK_
WWP1 Ubiquitylation K328 -0.364 0.487 _SSSAFEAAK(gl)SR_
WWP1 Ubiquitylation K350 0.049 0.396 _VYYVDHVEK(gl)R_
WWP1 Ubiquitylation K446 -1.514 -1.539 _EFDPLGPLPPGWEK(gl)R_
WWP1 Ubiquitylation K478 -1.265 _SQGQLNEK(gl)PLPEGWEMR_
WWP1 Ubiquitylation K513 -0.564 1.593 _TGK(gl)SALDNGPQIAYVR_
WWP1 Ubiquitylation K536 -1.895 1.126 _SSVTK(gl)GGPQIAYER_
WWP1 Ubiquitylation K861 -0.810 0.596 _VGK(gl)ENWLPR_
YAP1 Phosphorylation S61 -0.064 0.017 _GDS(ph)ETDLEALFNAVMNPK_
YAP1 Phosphorylation T63 -0.159 -0.257 _GDSET(ph)DLEALFNAVM(ox)NPK_
YAP1 Phosphorylation T110 0.467 _QAST(ph)DAGTAGALTPQHVR_
YAP1 Phosphorylation S127 -1.544 _AHS(ph)SPASLQLGAVSPGTLTPTGVVSGPAATPTAQHLR_
YAP1 Phosphorylation S131 -1.256 -1.096 _AHSSPAS(ph)LQLGAVSPGTLTPTGVVSGPAATPTAQHLR_
YAP1 Ubiquitylation K315 -0.002 _LQQLQMEK(gl)ER_
YAP1 Ubiquitylation K321 -1.043 _LK(gl)QQELLR_
YAP1 Ubiquitylation K342 -0.589 _NINPSTANSPK(gl)CQELALR_
YAP1 Phosphorylation S367 0.272 _SQLPTLEQDGGTQNPVSS(ph)PGMSQELR_
YAP1 Phosphorylation S397 -0.200 _DES(ph)TDSGLSM(ox)SSYSVPR_


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