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Query: FOSL2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
FOSL2 0 -0.517 0.940 -0.940

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
FOSL2 Phosphorylation S200 -0.517 _S(ph)PPAPGLQPMR_

Background Information for FOSL2:


Pubmed-FOSL2 »
Uniprot-FOSL2 »
Biogrid-FOSL2 »
ProteomicsDB-FOSL2 »

Tumorportal-FOSL2 »
COSMIC-FOSL2 »
GenomeRNAi-FOSL2 »
Genecards-FOSL2


Protein-protein Interactions for FOSL2
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait EGR1 Cat. description Hein, Mann, Cell 2015
Category members IP bait FOSL2 Cat. description Hein, Mann, Cell 2015
Category members IP bait JUN Cat. description Hein, Mann, Cell 2015
Category members IP bait JUNB Cat. description Hein, Mann, Cell 2015
Category members IP bait FOSL2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait JUNB Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in FOSL2
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Leuzip_Fos IPR000837 0
Category members bZIP IPR004827 0
Category members TF_DNA-bd IPR008917 0


Protein complexes (CORUM database) featuring FOSL2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring FOSL2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members GO Category GO:0006351 transcription, DNA-templated Database 1.07
Category members GO Category GO:0006366 transcription from RNA polymerase II promoter Database 0.96
Category members GO Category GO:0003690 double-stranded DNA binding Database 0.66
Category members GO Category GO:0042493 response to drug Database 0.66
Category members GO Category GO:0003700 sequence-specific DNA binding transcription factor activity Database 0.63
Category members GO Category GO:0009612 response to mechanical stimulus Database 0.23
Category members GO Category GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding Database 0.21
Category members GO Category GO:0007565 female pregnancy Database 0.19
Category members GO Category GO:0006357 regulation of transcription from RNA polymerase II promoter Database 0.19
Category members GO Category GO:0043565 sequence-specific DNA binding Database 0.18
Category members GO Category GO:0032570 response to progesterone Database 0.1
Category members GO Category GO:0008219 cell death Database 0.08
Category members GO Category GO:0048146 positive regulation of fibroblast proliferation Database 0.05
Category members Pathway Pathway_1096 BIOCARTA_RANKL_PATHWAY 0 0
Category members Pathway Pathway_209 PID_DELTA_NP63_PATHWAY 0 0
Category members Pathway Pathway_440 PID_FRA_PATHWAY 0 0
Category members Pathway Pathway_443 PID_AP1_PATHWAY 0 0
Category members GO Category GO:0006355 regulation of transcription, DNA-dependent Database 0
Category members GO Category GO:0032870 cellular response to hormone stimulus Database 0
Category members GO Category GO:0043278 response to morphine Database 0
Category members GO Category GO:0051412 response to corticosterone Database 0
Category members GO Category GO:0051591 response to cAMP Database 0


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