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PID_FRA_PATHWAY
(Pathway_440)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
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Protein Results:

Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
JUN 3 -0.930 0.930 -0.126
TXLNG 1
USF2 1 0.080 -0.210 0.151 -0.093
USF2 1 0.080 -0.210 0.695 4.891
CCND1 1 -1.820 3.470
JUND 1 0.270 0.190
FOSL2 0 0.940 -0.940
HMOX1 0 0.330 0.220 -1.817 -1.289
EP300 0 -1.210 1.320 -1.089 -1.694 -0.723
NFATC2 0 -0.090 0.320
ATF4 0 -1.090 1.510
CCNA2 0 -0.530 0.260
CDKN2A 0 -0.080 -0.260 -0.556 -1.080 -3.270 -1.110
GJA1 0 -0.410 0.430
IVL 0 -0.390 -0.340
JUNB 0 0.350 -0.410
SP1 0 0.404 0.333 0.650

PTM Sites:

Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
ATF4 Phosphorylation S69 0.252 _AGSSEWLAVDGLVS(ph)PSNNSK_
ATF4 Phosphorylation S248 0.569 -0.323 _SLPS(ph)PGVLCGSAR_
ATF4 Ubiquitylation K267 -1.961 _PYDPPGEK(gl)MVAAK_
ATF4 Ubiquitylation K329 -0.035 _ADSLAK(gl)EIQYLK_
CCNA2 Ubiquitylation K54 -0.746 _AALAVLK(gl)SGNPR_
CCNA2 Ubiquitylation K68 -1.274 _GLAQQQRPK(gl)TR_
CCND1 Ubiquitylation K33 -0.490 _AMLK(gl)AEETCAPSVSYFK_
CCND1 Ubiquitylation K46 -1.016 -0.036 _AEETCAPSVSYFK(gl)CVQK_
CCND1 Ubiquitylation K95 -0.733 -0.137 _FLSLEPVK(gl)K_
CCND1 Ubiquitylation K96 -0.846 -0.155 _FLSLEPVKK(gl)_
CCND1 Ubiquitylation K238 0.245 _VIK(gl)CDPDCLR_
EP300 Phosphorylation S1038 -0.672 -0.349 _TEIKEEEDQPSTSATQSS(ph)PAPGQSK_
EP300 Phosphorylation S1726 0.994 0.627 _LGLGLDDESNNQQAAATQS(ph)PGDSRR_
EP300 Phosphorylation S2328 -1.092 0.725 _PQSQPPHSSPS(ph)PR_
FOSL2 Phosphorylation S200 -0.517 _S(ph)PPAPGLQPMR_
GJA1 Ubiquitylation K109 0.099 _LNKK(gl)EEELK_
GJA1 Ubiquitylation K128 0.209 1.057 _VAQTDGVNVDMHLK(gl)QIEIK_
GJA1 Ubiquitylation K136 -0.888 _FK(gl)YGIEEHGK_
GJA1 Ubiquitylation K243 0.152 0.237 _GK(gl)SDPYHATSGALSPAK_
GJA1 Ubiquitylation K258 -0.280 0.063 _SDPYHATSGALSPAK(gl)DCGSQK_
GJA1 Ubiquitylation K303 -0.106 0.280 _NYNK(gl)QASEQNWANYSAEQNR_
GJA1 Ubiquitylation K345 -0.464 _MGQAGSTISNSHAQPFDFPDDNQNSK(gl)K_
GJA1 Ubiquitylation K346 -1.004 -0.300 _MGQAGSTISNSHAQPFDFPDDNQNSKK(gl)_
GJA1 Phosphorylation S364 -0.300 _LAAGHELQPLAIVDQRPS(ph)SR_
GJA1 Phosphorylation S365 -0.300 _LAAGHELQPLAIVDQRPS(ph)SR_
GJA1 Phosphorylation S372 0.940 1.430 _AS(ph)SRPRPDDLEI_
GJA1 Phosphorylation S373 0.664 0.467 _ASS(ph)RPRPDDLEI_
HMOX1 Ubiquitylation K243 -0.972 _ASNK(gl)VQDSAPVETPR_
HMOX1 Ubiquitylation K256 -1.769 _GK(gl)PPLNTR_
JUN Phosphorylation S58 -0.167 -1.247 _AKNS(ph)DLLTSPDVGLLK_
JUN Phosphorylation T62 2.545 1.674 _NSDLLT(ph)SPDVGLLK_
JUN Phosphorylation S63 2.030 1.458 _NSDLLTS(ph)PDVGLLK_
JUN Ubiquitylation K70 9.213 _NSDLLTSPDVGLLK(gl)_
JUN Phosphorylation S73 1.499 0.845 _LAS(ph)PELER_
JUN Phosphorylation S243 -0.642 -1.399 _LQALKEEPQTVPEMPGETPPLS(ph)PIDMESQER_
JUN Ubiquitylation K309 1.034 0.155 _EQVAQLK(gl)QK_
JUNB Phosphorylation T255 -0.205 _DAT(ph)PPVS(ph)PINMEDQER_
JUNB Phosphorylation S259 -0.205 _DAT(ph)PPVS(ph)PINMEDQER_
JUND Phosphorylation S90 2.088 1.448 _ADGAPSAAPPDGLLAS(ph)PDLGLLK_
JUND Phosphorylation S255 -1.629 -1.982 _LAALKDEPQTVPDVPSFGES(ph)PPLSPIDMDTQER_
JUND Phosphorylation S259 -0.855 _LAALKDEPQTVPDVPSFGESPPLS(ph)PIDMDTQER_
NFATC2 Phosphorylation S53 -0.845 -1.099 _VAS(ph)PPSGPAYPDDVLDYGLKPYSPLASLSGEPPGR_
NFATC2 Phosphorylation T325 -0.605 0.168 _T(ph)SPDPSPVSAAPSK_
NFATC2 Phosphorylation S326 -0.605 0.168 _T(ph)SPDPSPVSAAPSK_
SP1 Phosphorylation S2 0.834 1.114 _(ac)S(ph)DQDHSMDEMTAVVK_
SP1 Phosphorylation S7 0.586 0.217 _(ac)SDQDHS(ph)MDEMTAVVK_
SP1 Phosphorylation S56 -0.154 _SSSTGSSSSTGGGGQES(ph)QPSPLALLAATCSR_
SP1 Phosphorylation S59 -0.217 -0.135 _SSSTGSSSSTGGGGQESQPS(ph)PLALLAATCSR_
TXLNG Phosphorylation S97 -0.010 0.641 _NLVS(ph)PAYCTQESR_
TXLNG Phosphorylation T102 1.816 0.423 _NLVSPAYCT(ph)QESREEIPGGEAR_
TXLNG Phosphorylation S105 1.805 0.514 _NLVSPAYCTQES(ph)REEIPGGEAR_
USF2 Ubiquitylation K269 -0.265 0.440 _IIPDCNADNSK(gl)TGASK_
USF2 Phosphorylation S279 -0.121 0.837 _GGILS(ph)KACDYIR_
USF2 Ubiquitylation K300 -0.172 _MQETFK(gl)EAER_


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