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Query: NFATC2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
NFATC2 0 -0.117 -0.090 0.320

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
NFATC2 Phosphorylation T325 -0.605 0.168 _T(ph)SPDPSPVSAAPSK_
NFATC2 Phosphorylation S326 -0.605 0.168 _T(ph)SPDPSPVSAAPSK_
NFATC2 Phosphorylation S53 -0.845 -1.099 _VAS(ph)PPSGPAYPDDVLDYGLKPYSPLASLSGEPPGR_

Background Information for NFATC2:


Pubmed-NFATC2 »
Uniprot-NFATC2 »
Biogrid-NFATC2 »
ProteomicsDB-NFATC2 »

Tumorportal-NFATC2 »
COSMIC-NFATC2 »
GenomeRNAi-NFATC2 »
Genecards-NFATC2


Protein-protein Interactions for NFATC2
Show screen data for Category Name and Description Link to cat description Data Source


Protein Domains in NFATC2
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members IPT IPR002909 0.11
Category members NFAT IPR008366 0
Category members p53-like_TF_DNA-bd IPR008967 0
Category members RHD IPR011539 0
Category members Ig_E-set IPR014756 0


Protein complexes (CORUM database) featuring NFATC2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 2693 NFAT-JUN-FOS DNA-protein complex Database 0


Categories featuring NFATC2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005654 nucleoplasm Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0030529 ribonucleoprotein complex Database 8.45
Category members GO Category GO:0006974 cellular response to DNA damage stimulus Database 3.57
Category members GO Category GO:0015629 actin cytoskeleton Database 2.22
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members Pathway Pathway_1023 PID_NFAT_3PATHWAY 0 1.46
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0006351 transcription, DNA-templated Database 1.07
Category members GO Category GO:0042493 response to drug Database 0.66
Category members GO Category GO:0003700 sequence-specific DNA binding transcription factor activity Database 0.63
Category members GO Category GO:0038095 Fc-epsilon receptor signaling pathway Database 0.36
Category members GO Category GO:0045893 positive regulation of transcription, DNA-dependent Database 0.28
Category members Pathway Pathway_587 KEGG_T_CELL_RECEPTOR_SIGNALING_PATHWAY 0 0.25
Category members Pathway Pathway_535 SIG_BCR_SIGNALING_PATHWAY 0 0.24
Category members Pathway Pathway_648 KEGG_B_CELL_RECEPTOR_SIGNALING_PATHWAY 0 0.19
Category members GO Category GO:0005667 transcription factor complex Database 0.19
Category members GO Category GO:0043565 sequence-specific DNA binding Database 0.18
Category members Pathway Pathway_686 BIOCARTA_BCR_PATHWAY 0 0.16
Category members GO Category GO:0045944 positive regulation of transcription from RNA polymerase II promoter Database 0.13
Category members Pathway Pathway_698 BIOCARTA_CALCINEURIN_PATHWAY 0 0.11
Category members Pathway Pathway_679 KEGG_WNT_SIGNALING_PATHWAY 0 0.09
Category members Pathway Pathway_417 PID_WNT_NONCANONICAL_PATHWAY 0 0.09
Category members GO Category GO:0045087 innate immune response Database 0.05
Category members Pathway Pathway_1034 KEGG_AXON_GUIDANCE 0 0.04
Category members Pathway Pathway_543 BIOCARTA_TCR_PATHWAY 0 0.03
Category members GO Category GO:0044212 transcription regulatory region DNA binding Database 0
Category members Pathway Pathway_1130 BIOCARTA_GATA3_PATHWAY 0 0
Category members Pathway Pathway_1144 BIOCARTA_MEF2D_PATHWAY 0 0
Category members Pathway Pathway_218 BIOCARTA_GPCR_PATHWAY 0 0
Category members Pathway Pathway_436 KEGG_VEGF_SIGNALING_PATHWAY 0 0
Category members Pathway Pathway_440 PID_FRA_PATHWAY 0 0
Category members Pathway Pathway_443 PID_AP1_PATHWAY 0 0
Category members Pathway Pathway_489 PID_NFAT_TFPATHWAY 0 0
Category members Pathway Pathway_500 PID_FCER1_PATHWAY 0 0
Category members Pathway Pathway_524 BIOCARTA_FMLP_PATHWAY 0 0
Category members Pathway Pathway_574 BIOCARTA_HDAC_PATHWAY 0 0
Category members Pathway Pathway_597 BIOCARTA_FCER1_PATHWAY 0 0
Category members Pathway Pathway_641 BIOCARTA_NFAT_PATHWAY 0 0
Category members Pathway Pathway_646 KEGG_NATURAL_KILLER_CELL_MEDIATED_CYTOTOXICITY 0 0
Category members Pathway Pathway_702 BIOCARTA_VIP_PATHWAY 0 0
Category members Pathway Pathway_715 KEGG_MAPK_SIGNALING_PATHWAY 0 0
Category members Pathway Pathway_732 PID_TCR_CALCIUM_PATHWAY 0 0
Category members Pathway Pathway_897 PID_CD8_TCR_DOWNSTREAM_PATHWAY 0 0
Category members GO Category GO:0001816 cytokine production Database 0
Category members GO Category GO:0006355 regulation of transcription, DNA-dependent Database 0
Category members GO Category GO:0010628 positive regulation of gene expression Database 0
Category members GO Category GO:0016477 cell migration Database 0
Category members GO Category GO:0030890 positive regulation of B cell proliferation Database 0
Category members GO Category GO:0050853 B cell receptor signaling pathway Database 0


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