RNAi screen result	RNAPII IP (MG132)	CSB IP	CSB IP (MG132)	Chrom.	Chrom. (MG132)	Ubi /Phospo	Ubi /Phospho (MG132)
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Gene name	MGoogle Score	RNAi high	RNAi low	RNAPII-IP (MG132)	CSB-IP	CSB-IP (MG132)	Chrom.	Chrom. (MG132)
JUN	3	-0.930	0.930			-0.126
GSK3B	2	1.020	-0.870				-1.128	1.091
AKT3	2	0.580	-0.030	-0.194
AKT3	2	0.580	-0.030
PIK3R2	1	2.740	-1.180				0.269	0.348
RAC2	1	-1.520	2.710	0.486			-0.364	-0.568
RAF1	1	2.020	-1.230
KRAS	1	-0.510	0.620				1.031	0.887
KRAS	1	-0.510	0.620				0.246	-0.346
BCL10	1	0.000	0.200
MAP2K1	1	-1.590	2.780
NRAS	1	1.810	-0.720				0.246	-0.346
LYN	1	-1.790	3.770
LYN	1	-1.790	3.770
PIK3CB	0	-1.390	2.350
PIK3CB	0	-0.710	1.450
NFATC4	0	0.060	0.210
NFATC2	0	-0.090	0.320
MAPK3	0
NFAT5	0	0.240	-0.760
IKBKB	0	0.400	0.610
AKT2	0	-1.420	2.210	-0.194
PPP3CB	0	-1.240	2.140		-0.298	1.130
PPP3CB	0	-1.240	2.140				0.923	0.537
NFKB1	0	0.720	-0.810
CD81	0	0.850	-0.400				0.408	0.204
SOS1	0	0.500	-0.620	-0.570
PIK3R3	0	-0.140	-0.480
PIK3R3	0	-0.140	-0.480				-0.441	0.147
PPP3CC	0	-0.380	1.050		-0.298	1.130
PPP3CC	0	-0.380	1.050				0.923	0.537
PIK3CA	0
MAP2K2	0	-0.610	0.080
MAP2K2	0	-0.610	0.080
RAC1	0	-0.580	1.580	0.486			-0.364	-0.568
PPP3CA	0	1.550	-1.230		-0.298	1.130
PPP3CA	0	1.550	-1.230				0.923	0.537
AKT1	0	-0.050	0.700
AKT1	0	0.860	-0.040
PIK3R1	0	1.910	-1.220				-0.441	0.147
NFKBIE	0	1.270	-0.670
RASGRP3	0	0.570	0.240
PRKCB	0	0.260	-0.530
PRKCB	0	0.260	-0.530				0.349	0.585
RAC3	0	0.210	0.290
RELA	0	-1.130	1.600	0.793
HRAS	0	1.470	-0.520
GRB2	0	-0.240	0.300		-1.021	0.057	0.906
IFITM1	0	0.560	-0.530
IFITM1	0	1.200	-0.770
CHUK	0			-0.480

Gene name	PTM type	PTM site	UV	UV (MG132)	Sequence
AKT1	Phosphorylation	S124	0.252	0.311	_SGS(ph)PSDNSGAEEMEVSLAKPK_
AKT1	Phosphorylation	S126	-0.241		_SGSPS(ph)DNSGAEEM(ox)EVSLAK_
AKT1	Ubiquitylation	K301	0.988		_EGIK(gl)DGATMK_
AKT2	Ubiquitylation	K14	0.306	0.070	_EGWLHK(gl)R_
AKT2	Ubiquitylation	K111	1.082		_AIQMVANSLK(gl)QR_
AKT2	Ubiquitylation	K160		0.251	_LLGK(gl)GTFGK_
AKT2	Phosphorylation	T451	-0.091	-0.612	_YFDDEFTAQSITIT(ph)PPDRYDSLGLLELDQR_
AKT2	Phosphorylation	Y456		-0.265	_YFDDEFTAQSITITPPDRY(ph)DSLGLLELDQR_
AKT3	Ubiquitylation	K14	0.306	0.070	_EGWLHK(gl)R_
AKT3	Ubiquitylation	K14	4.941	5.277	_EGWVQK(gl)R_
AKT3	Ubiquitylation	K111	1.082		_AIQMVANSLK(gl)QR_
AKT3	Phosphorylation	S120		1.097	_MNCS(ph)PTSQIDNIGEEEMDASTTHHK_
AKT3	Ubiquitylation	K160		0.251	_LLGK(gl)GTFGK_
AKT3	Phosphorylation	T451	-0.091	-0.612	_YFDDEFTAQSITIT(ph)PPDRYDSLGLLELDQR_
AKT3	Phosphorylation	Y456		-0.265	_YFDDEFTAQSITITPPDRY(ph)DSLGLLELDQR_
BCL10	Phosphorylation	S138	1.515	1.393	_SNS(ph)DESNFSEK_
CD81	Ubiquitylation	K182	-2.166		_QFYDQALQQAVVDDDANNAK(gl)AVVK_
CHUK	Ubiquitylation	K296		-1.637	_GGPVDLTLK(gl)QPR_
GRB2	Ubiquitylation	K10	0.146		_YDFK(gl)ATADDELSFK_
GRB2	Ubiquitylation	K20	-0.078		_ATADDELSFK(gl)R_
GRB2	Ubiquitylation	K69	-0.362	0.641	_AK(gl)AEEMLSK_
GRB2	Ubiquitylation	K76	0.754		_AEEMLSK(gl)QR_
GRB2	Ubiquitylation	K109	0.381	-0.002	_FGNDVQHFK(gl)VLR_
GSK3B	Phosphorylation	S9	-0.483	0.010	_TTS(ph)FAESCKPVQQPSAFGSMK_
GSK3B	Ubiquitylation	K85		-0.204	_LCDSGELVAIK(gl)K_
GSK3B	Ubiquitylation	K86		-0.204	_LCDSGELVAIK(gl)K_
GSK3B	Phosphorylation	S215	0.296	0.477	_GEPNVS(ph)YICSR_
GSK3B	Phosphorylation	Y216	0.356	0.376	_GEPNVSY(ph)ICSR_
GSK3B	Phosphorylation	T390	2.800	2.527	_IQAAAST(ph)PTNATAASDANTGDR_
HRAS	Ubiquitylation	K170	-1.005		_K(gl)LNPPDESGPGCMSCK_
IFITM1	Ubiquitylation	K3	-0.716	-1.338	_M(ox)HK(gl)EEHEVAVLGPPPSTILPR_
IKBKB	Ubiquitylation	K106	0.253		_K(gl)YLNQFENCCGLR_
IKBKB	Phosphorylation	S672	0.670	0.244	_GPVSGS(ph)PDSMNASR_
JUN	Phosphorylation	S58	-0.167	-1.247	_AKNS(ph)DLLTSPDVGLLK_
JUN	Phosphorylation	T62	2.545	1.674	_NSDLLT(ph)SPDVGLLK_
JUN	Phosphorylation	S63	2.030	1.458	_NSDLLTS(ph)PDVGLLK_
JUN	Ubiquitylation	K70	9.213		_NSDLLTSPDVGLLK(gl)_
JUN	Phosphorylation	S73	1.499	0.845	_LAS(ph)PELER_
JUN	Phosphorylation	S243	-0.642	-1.399	_LQALKEEPQTVPEMPGETPPLS(ph)PIDMESQER_
JUN	Ubiquitylation	K309	1.034	0.155	_EQVAQLK(gl)QK_
KRAS	Ubiquitylation	K128	1.528	1.433	_TVDTK(gl)QAHELAK_
KRAS	Ubiquitylation	K235	0.591	0.087	_TVDTK(gl)QAQDLAR_
KRAS	Ubiquitylation	K254	-0.450	-0.156	_SYGIPFIETSAK(gl)TR_
LYN	Ubiquitylation	K20	-0.592		_GKDSLSDDGVDLK(gl)TQPVR_
LYN	Ubiquitylation	K40	0.100		_DPTSNK(gl)QQRPVPESQLLPGQR_
LYN	Phosphorylation	S104	0.944	0.841	_DSLS(ph)DDGVDLK_
LYN	Ubiquitylation	K213	0.441		_HYQK(gl)QADGLCR_
LYN	Ubiquitylation	K477	-0.191		_VENCPDELYDIMK(gl)MCWK_
MAP2K1	Ubiquitylation	K192	-0.205	-0.241	_DVK(gl)PSNILVNSR_
MAP2K1	Phosphorylation	S385		0.066	_RSDAEEVDFAGWLCSTIGLNQPS(ph)TPTHAAGV_
MAP2K1	Phosphorylation	T386		0.377	_RSDAEEVDFAGWLCSTIGLNQPST(ph)PTHAAGV_
MAP2K2	Phosphorylation	S23	0.873	0.258	_RKPVLPALTINPTIAEGPS(ph)PTSEGASEANLVDLQK_
MAP2K2	Phosphorylation	T25		0.439	_RKPVLPALTINPTIAEGPSPT(ph)SEGASEANLVDLQK_
MAP2K2	Ubiquitylation	K192	-0.205	-0.241	_DVK(gl)PSNILVNSR_
MAP2K2	Phosphorylation	S293		-0.361	_ELEAIFGRPVVDGEEGEPHS(ph)ISPR_
MAP2K2	Phosphorylation	S295	-0.234	0.026	_ELEAIFGRPVVDGEEGEPHSIS(ph)PR_
MAP2K2	Phosphorylation	T394	0.570	0.158	_LNQPGT(ph)PTR_
MAPK3	Phosphorylation	Y204	-0.807	-2.487	_IADPEHDHTGFLTEY(ph)VATR_
MAPK3	Ubiquitylation	K289		-0.608	_NYLQSLPSKTK(gl)_
NFAT5	Phosphorylation	S163		-0.941	_RHTVLYIS(ph)PPPEDLLDNSR_
NFAT5	Phosphorylation	S578	1.128	1.267	_KEIS(ph)SPARPCSFEEAM(ox)K_
NFAT5	Phosphorylation	S579		1.019	_KEISS(ph)PARPCSFEEAM(ox)K_
NFATC2	Phosphorylation	S53	-0.845	-1.099	_VAS(ph)PPSGPAYPDDVLDYGLKPYSPLASLSGEPPGR_
NFATC2	Phosphorylation	T325	-0.605	0.168	_T(ph)SPDPSPVSAAPSK_
NFATC2	Phosphorylation	S326	-0.605	0.168	_T(ph)SPDPSPVSAAPSK_
NFATC4	Phosphorylation	S289	-1.594	-0.700	_RGS(ph)LGEEGSEPPPPPPLPLAR_
NFATC4	Phosphorylation	S311		0.305	_DPGS(ph)PGPFDYVGAPPAESIPQK_
NFATC4	Phosphorylation	S334	0.917	0.074	_RTS(ph)SEQAVALPR_
NFKB1	Phosphorylation	S907	-0.025	0.113	_TTSQAHSLPLS(ph)PASTR_
NFKBIE	Ubiquitylation	K316		-0.248	_ALVLK(gl)GASR_
NRAS	Ubiquitylation	K128	1.528	1.433	_TVDTK(gl)QAHELAK_
PIK3CA	Ubiquitylation	K864	0.390	0.588	_NSHTIM(ox)QIQCK(gl)GGLK_
PIK3CA	Ubiquitylation	K868	0.204	0.651	_NSHTIM(ox)QIQCKGGLK(gl)_
PIK3CA	Ubiquitylation	K974	-0.273		_GAQECTK(gl)TREFER_
PIK3CB	Ubiquitylation	K1044		0.990	_SEEEALKQFKQK(gl)_
PIK3R2	Phosphorylation	S262		-2.237	_APPPPS(ph)SPPPGGAPDGSEPSPDFPALLVEK_
PIK3R2	Phosphorylation	S263		-2.237	_APPPPS(ph)SPPPGGAPDGSEPSPDFPALLVEK_
PIK3R2	Ubiquitylation	K500	-0.189		_IFEEQGQTQEK(gl)CSK_
PIK3R2	Ubiquitylation	K541	-0.609		_TK(gl)LEQQLR_
PIK3R2	Ubiquitylation	K564	-0.431	-1.022	_MNSLK(gl)PDLMQLR_
PIK3R3	Ubiquitylation	K226		-0.376	_YQQDQLVKEDNIDAVGKK(gl)_
PIK3R3	Ubiquitylation	K320		0.385	_LGEIHDSK(gl)MR_
PPP3CA	Ubiquitylation	K32	-0.137		_LTAK(gl)EVFDNDGKPR_
PPP3CA	Ubiquitylation	K56		0.132	_VDVLK(gl)NHLVK_
PPP3CA	Ubiquitylation	K323		0.705	_AAVLK(gl)YENNVMNIR_
PPP3CA	Ubiquitylation	K405		0.078	_AIGK(gl)MAR_
PPP3CB	Ubiquitylation	K32	-0.137		_LTAK(gl)EVFDNDGKPR_
PPP3CB	Ubiquitylation	K56		0.132	_VDVLK(gl)NHLVK_
PPP3CB	Ubiquitylation	K323		0.705	_AAVLK(gl)YENNVMNIR_
PPP3CB	Ubiquitylation	K405		0.078	_AIGK(gl)MAR_
PPP3CC	Ubiquitylation	K32	-0.137		_LTAK(gl)EVFDNDGKPR_
PPP3CC	Ubiquitylation	K56		0.132	_VDVLK(gl)NHLVK_
PPP3CC	Ubiquitylation	K323		0.705	_AAVLK(gl)YENNVMNIR_
PPP3CC	Ubiquitylation	K405		0.078	_AIGK(gl)MAR_
PRKCB	Phosphorylation	S10	-0.650	0.036	_(ac)ADVFPGNDS(ph)TASQDVANR_
PRKCB	Phosphorylation	S13	-1.038	0.335	_(ac)ADVFPGNDSTAS(ph)QDVANR_
PRKCB	Phosphorylation	S226	0.693	0.415	_STLNPQWNES(ph)FTFK_
PRKCB	Ubiquitylation	K315	0.213	0.518	_ISQGTK(gl)VPEEK_
RAC1	Ubiquitylation	K115	-1.745	-0.215	_AK(gl)WYPEVR_
RAC1	Ubiquitylation	K142	0.492		_LDLRDDK(gl)DTIEK_
RAC1	Ubiquitylation	K152	0.099	-0.292	_K(gl)LTPITYPQGLAMAK_
RAC1	Ubiquitylation	K166	-0.981	-0.655	_LTPITYPQGLAMAK(gl)EIGAVK_
RAC1	Ubiquitylation	K172	1.026	0.412	_EIGAVK(gl)YLECSALTQR_
RAC1	Ubiquitylation	K185	-0.113	0.578	_GLK(gl)TVFDEAIR_
RAC1	Ubiquitylation	K202	-1.379	-1.447	_AVLCPPPVK(gl)KR_
RAC1	Ubiquitylation	K203	-1.708	-1.447	_AVLCPPPVKK(gl)_
RAC2	Ubiquitylation	K115	-1.745	-0.215	_AK(gl)WYPEVR_
RAC2	Ubiquitylation	K142	0.492		_LDLRDDK(gl)DTIEK_
RAC2	Ubiquitylation	K152	0.099	-0.292	_K(gl)LTPITYPQGLAMAK_
RAC2	Ubiquitylation	K166	-0.981	-0.655	_LTPITYPQGLAMAK(gl)EIGAVK_
RAC2	Ubiquitylation	K172	1.026	0.412	_EIGAVK(gl)YLECSALTQR_
RAC2	Ubiquitylation	K185	-0.113	0.578	_GLK(gl)TVFDEAIR_
RAC2	Ubiquitylation	K202	-1.379	-1.447	_AVLCPPPVK(gl)KR_
RAC2	Ubiquitylation	K203	-1.708	-1.447	_AVLCPPPVKK(gl)_
RAC3	Ubiquitylation	K153		-0.133	_EIGSVK(gl)YLECSALTQR_
RAC3	Ubiquitylation	K183		-1.447	_AVLCPPPVK(gl)K_
RAC3	Ubiquitylation	K184	-1.812	-1.447	_AVLCPPPVKK(gl)_
RAF1	Phosphorylation	S29	0.028	-0.571	_DAVFDGSSCIS(ph)PTIVQQFGYQR_
RAF1	Phosphorylation	T31	0.028	-0.669	_DAVFDGSSCIS(ph)PTIVQQFGYQR_
RAF1	Phosphorylation	S244		0.053	_YSTPHAFTFNTSS(ph)PSSEGSLSQR_
RAF1	Phosphorylation	S259	-0.069	0.054	_STS(ph)TPNVHM(ox)VSTTLPVDSR_
RAF1	Phosphorylation	S301		-0.651	_SHSESASPSALSSSPNNLS(ph)PTGWSQPK_
RAF1	Phosphorylation	T303		-0.664	_SHSESASPSALSSSPNNLSPT(ph)GWSQPK_
RAF1	Phosphorylation	S497		-0.449	_SRWS(ph)GSQQVEQPTGSVLWMAPEVIR_
RAF1	Phosphorylation	S621	0.212	0.271	_SAS(ph)EPSLHR_
RAF1	Phosphorylation	S642	-0.197	0.463	_AAHTEDINACTLTTS(ph)PR_
RASGRP3	Phosphorylation	S390	0.183	0.695	_SPTS(ph)PTTPNK_
SOS1	Phosphorylation	S1082	0.278		_IPESETESTASAPNS(ph)PR_
SOS1	Phosphorylation	S1166	0.097	-0.094	_RPESAPAES(ph)SPSK_