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Query: RAC3

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
RAC3 0 -1.655 0.210 0.290

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
RAC3 Ubiquitylation K153 -0.133 _EIGSVK(gl)YLECSALTQR_
RAC3 Ubiquitylation K183 -1.447 _AVLCPPPVK(gl)K_
RAC3 Ubiquitylation K184 -1.812 -1.447 _AVLCPPPVKK(gl)_

Background Information for RAC3:


Pubmed-RAC3 »
Uniprot-RAC3 »
Biogrid-RAC3 »
ProteomicsDB-RAC3 »

Tumorportal-RAC3 »
COSMIC-RAC3 »
GenomeRNAi-RAC3 »
Genecards-RAC3


Protein-protein Interactions for RAC3
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait RAC1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RAC2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RAP1GDS1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SLC7A1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SLC9A6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in RAC3
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members P-loop_NTPase IPR027417 2.83
Category members Small_GTPase_ARF/SAR IPR006689 0.8
Category members Small_GTPase_Ras IPR020849 0.7
Category members Small_GTPase_Rho IPR003578 0.65
Category members Small_GTPase IPR001806 0.65
Category members Small_GTPase_Rab_type IPR003579 0.51
Category members MIRO-like IPR013684 0.4
Category members Small_GTP-bd_dom IPR005225 0.32


Protein complexes (CORUM database) featuring RAC3
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring RAC3
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members DDR Literature pubmedid:24055347 Jungmichel et al., 2013 UV-stimulated poly(ADP-Ribosyl)ation targets Jungmichel et al., 2013 INF
Category members GO Category GO:0015031 protein transport Database 3.48
Category members GO Category GO:0030027 lamellipodium Database 1.77
Category members GO Category GO:0030426 growth cone Database 1.61
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members Pathway Pathway_595 KEGG_FOCAL_ADHESION 0 1.08
Category members GO Category GO:0030036 actin cytoskeleton organization Database 1.08
Category members Pathway Pathway_634 KEGG_COLORECTAL_CANCER 0 0.98
Category members GO Category GO:0016020 membrane Database 0.52
Category members Pathway Pathway_747 KEGG_ADHERENS_JUNCTION 0 0.43
Category members GO Category GO:0007264 small GTPase mediated signal transduction Database 0.37
Category members GO Category GO:0005622 intracellular Database 0.32
Category members GO Category GO:0006184 GTP catabolic process Database 0.29
Category members GO Category GO:0051056 regulation of small GTPase mediated signal transduction Database 0.25
Category members Pathway Pathway_648 KEGG_B_CELL_RECEPTOR_SIGNALING_PATHWAY 0 0.19
Category members GO Category GO:0005525 GTP binding Database 0.16
Category members GO Category GO:0003924 GTPase activity Database 0.16
Category members Pathway Pathway_649 KEGG_PANCREATIC_CANCER 0 0.15
Category members GO Category GO:0031175 neuron projection development Database 0.12
Category members Pathway Pathway_679 KEGG_WNT_SIGNALING_PATHWAY 0 0.09
Category members Pathway Pathway_580 KEGG_REGULATION_OF_ACTIN_CYTOSKELETON 0 0.08
Category members GO Category GO:0043005 neuron projection Database 0.08
Category members Pathway Pathway_1034 KEGG_AXON_GUIDANCE 0 0.04
Category members GO Category GO:0050885 neuromuscular process controlling balance Database 0.02
Category members GO Category GO:0031941 filamentous actin Database 0.01
Category members Pathway Pathway_1014 KEGG_VIRAL_MYOCARDITIS 0 0
Category members Pathway Pathway_24 KEGG_PATHWAYS_IN_CANCER 0 0
Category members Pathway Pathway_436 KEGG_VEGF_SIGNALING_PATHWAY 0 0
Category members Pathway Pathway_519 REACTOME_SIGNALING_BY_RHO_GTPASES 0 0
Category members Pathway Pathway_530 KEGG_FC_EPSILON_RI_SIGNALING_PATHWAY 0 0
Category members Pathway Pathway_646 KEGG_NATURAL_KILLER_CELL_MEDIATED_CYTOTOXICITY 0 0
Category members Pathway Pathway_715 KEGG_MAPK_SIGNALING_PATHWAY 0 0
Category members GO Category GO:0007165 signal transduction Database 0
Category members GO Category GO:0012505 endomembrane system Database 0
Category members GO Category GO:0030031 cell projection assembly Database 0
Category members GO Category GO:0035556 intracellular signal transduction Database 0
Category members GO Category GO:0043025 neuronal cell body Database 0
Category members GO Category GO:0050905 neuromuscular process Database 0


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