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Query: NFKBIE

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
NFKBIE 0 -0.248 1.270 -0.670

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
NFKBIE Ubiquitylation K316 -0.248 _ALVLK(gl)GASR_

Background Information for NFKBIE:


Pubmed-NFKBIE »
Uniprot-NFKBIE »
Biogrid-NFKBIE »
ProteomicsDB-NFKBIE »

Tumorportal-NFKBIE »
COSMIC-NFKBIE »
GenomeRNAi-NFKBIE »
Genecards-NFKBIE


Protein-protein Interactions for NFKBIE
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait NFKBIA Cat. description Hein, Mann, Cell 2015
Category members IP bait PRPF4 Cat. description Hein, Mann, Cell 2015
Category members IP bait SKA3 Cat. description Hein, Mann, Cell 2015
Category members IP bait TPX2 Cat. description Hein, Mann, Cell 2015
Category members IP bait UBR5 Cat. description Hein, Mann, Cell 2015
Category members IP bait YEATS4 Cat. description Hein, Mann, Cell 2015
Category members IP bait C2orf27B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait REL Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RELB Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in NFKBIE
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Ankyrin_rpt IPR002110 0
Category members Ankyrin_rpt-contain_dom IPR020683 0


Protein complexes (CORUM database) featuring NFKBIE
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 5193 TNF-alpha/NF-kappa B signaling complex (CHUK, KPNA3, NFKB2, NFKBIB, REL, IKBKG, NFKB1, NFKBIE, RELB, NFKBIA, RELA, TNIP2) Database 0.03
Category members Corum 5230 CHUK-NFKB2-REL-IKBKG-SPAG9-NFKB1-NFKBIE-COPB2-TNIP1-NFKBIA-RELA-TNIP2 complex Database 0
Category members Corum 5465 IKB(epsilon)-RELA-cREL complex Database 0


Categories featuring NFKBIE
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members Pathway Pathway_621 REACTOME_ADAPTIVE_IMMUNE_SYSTEM 0 4.72
Category members Pathway Pathway_458 REACTOME_IMMUNE_SYSTEM 0 3
Category members Pathway Pathway_660 REACTOME_SIGNALING_BY_THE_B_CELL_RECEPTOR_BCR 0 2.12
Category members Pathway Pathway_706 REACTOME_DOWNSTREAM_SIGNALING_EVENTS_OF_B_CELL_RECEPTOR_BCR 0 1.96
Category members Pathway Pathway_608 SIG_CD40PATHWAYMAP 0 0.89
Category members Pathway Pathway_804 REACTOME_ACTIVATION_OF_NF_KAPPAB_IN_B_CELLS 0 0.86
Category members Pathway Pathway_529 KEGG_NEUROTROPHIN_SIGNALING_PATHWAY 0 0.75
Category members GO Category GO:0048471 perinuclear region of cytoplasm Database 0.39
Category members GO Category GO:0005794 Golgi apparatus Database 0.27
Category members Pathway Pathway_587 KEGG_T_CELL_RECEPTOR_SIGNALING_PATHWAY 0 0.25
Category members Pathway Pathway_648 KEGG_B_CELL_RECEPTOR_SIGNALING_PATHWAY 0 0.19
Category members Pathway Pathway_514 ST_GAQ_PATHWAY 0 0.17
Category members GO Category GO:0042994 cytoplasmic sequestering of transcription factor Database 0.14
Category members Pathway Pathway_386 ST_FAS_SIGNALING_PATHWAY 0 0.02
Category members Pathway Pathway_1021 ST_TUMOR_NECROSIS_FACTOR_PATHWAY 0 0
Category members Pathway Pathway_387 ST_T_CELL_SIGNAL_TRANSDUCTION 0 0
Category members Pathway Pathway_40 KEGG_ADIPOCYTOKINE_SIGNALING_PATHWAY 0 0
Category members Pathway Pathway_515 ST_B_CELL_ANTIGEN_RECEPTOR 0 0
Category members Pathway Pathway_658 ST_GA13_PATHWAY 0 0
Category members GO Category GO:0042942 D-serine transport Database 0


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