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Results for the Category
ST_FAS_SIGNALING_PATHWAY
(Pathway_386)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
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Protein Results:

 Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
PARP1 2
PARP1 2 -0.200 0.357 0.412 0.442 0.293
DFFA 2 -0.290 -0.220
RALBP1 1 -1.890 3.240
BAK1 1 0.710 0.160 -0.419 2.039
MAPK9 1 0.110 -0.490
CASP8 1 1.120 -1.090
CAD 1 1.760 -0.990 -0.363 -0.027 0.051
EZR 1 -0.240 -0.210 2.501 -2.209 0.246 0.091
PFN1 1 -0.430 -0.180 0.002 2.497 -0.084 0.348 -0.059
CSNK1A1 1 0.080 -0.140 2.048 -0.562 0.195 -0.389 0.187
TRAF2 1 -0.570 0.540
TRAF2 1 -0.570 0.540
TONSL 1 -1.900 3.540 -0.261 -3.160 0.665 1.051
AGFG1 1 -1.660 2.550
MAPK8IP2 0 1.730 -1.220
FAS 0 1.380 -1.070
FAS 0 1.380 -1.070
MAP2K4 0 -0.300 0.320
ROCK1 0 -1.420 2.380 -0.112 -0.732
PFN2 0 -0.250 -0.070 0.715 1.366
PFN2 0 -0.250 -0.070
MAP2K7 0 0.180 -0.660 -2.110
NFKB2 0 1.750 -0.820
BAX 0 1.590 -1.170 0.811 0.359
TPX2 0 -0.652 -0.369
TPX2 0 -0.850 0.408
MAP3K1 0 0.750 -1.270
XIAP 0 0.600 -0.210
XIAP 0 0.600 -0.210 -1.128
NFAT5 0 0.240 -0.760
BFAR 0 0.270 -0.700
MET 0 -0.010 -0.330
HSPB1 0 0.710 -0.660 -0.632
NFKB1 0 0.720 -0.810
CDK2AP1 0 -0.720 0.500 -0.120 0.651
CDK2AP1 0 -0.720 0.500 0.267
ALG2 0 0.490 -0.760 0.103 0.159
EPHB2 0 -0.630 0.780 0.221
EPHB2 0 -0.630 0.780
RIPK1 0 -0.190 0.440
TP53 0 -1.070 1.050 -2.808 0.076 -0.094 0.436 0.497
NFKBIE 0 1.270 -0.670
EGFR 0 -0.580 0.520 0.513 0.090
DEDD 0 0.120 -0.510
DEDD2 0 0.690 -0.270
PTPN13 0 0.510 -0.610 0.549 0.504
CASP3 0 0.570 -0.390
TUFM 0 0.660 -0.360 0.254 0.270 -0.618 0.336 0.344
DIABLO 0 0.740 -0.290 0.517 0.500
DIABLO 0 0.740 -0.290 -0.061
FAF1 0 0.870 -0.650 0.213
MAP3K5 0 0.710 -0.770
DAXX 0 0.430 -1.030
DAXX 0 0.430 -1.030 -0.712 0.311

PTM Sites:

 Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
AGFG1 Phosphorylation S179 -0.502 _GTPS(ph)QSPVVGR_
AGFG1 Phosphorylation S181 -0.503 -0.338 _GTPSQS(ph)PVVGR_
BAX Ubiquitylation K57 -1.174 _MGGEAPELALDPVPQDASTK(gl)K_
BAX Ubiquitylation K58 -1.718 -1.174 _MGGEAPELALDPVPQDASTKK(gl)_
BAX Ubiquitylation K64 0.708 1.306 _LSECLK(gl)R_
BFAR Ubiquitylation K252 -0.414 _ALGVK(gl)PPQNLWEYK_
BFAR Ubiquitylation K387 0.038 _SELK(gl)TVPQR_
CAD Ubiquitylation K739 -0.732 -0.798 _NSVTGGTAAFEPSVDYCVVK(gl)IPR_
CAD Ubiquitylation K760 0.489 _IGSCMK(gl)SVGEVMGIGR_
CAD Ubiquitylation K778 -0.005 _SFEEAFQK(gl)ALR_
CAD Ubiquitylation K1119 -1.239 _FLSSAAAVSK(gl)EHPVVISK_
CAD Ubiquitylation K1211 -0.235 -0.502 _DDQLK(gl)VIECNVR_
CAD Ubiquitylation K1309 0.012 -0.277 _AMLSTGFK(gl)IPK_
CAD Ubiquitylation K1325 -0.719 -0.613 _NK(gl)SELLPTVR_
CAD Phosphorylation S1406 0.530 0.612 _RLS(ph)SFVTK_
CAD Ubiquitylation K1411 -0.215 -0.224 _RLSSFVTK(gl)GYR_
CAD Ubiquitylation K1460 0.321 _VHVDCMTSQK(gl)LVR_
CAD Ubiquitylation K1657 2.804 -1.545 _LGPGK(gl)GEVRPELGSR_
CAD Phosphorylation T1827 -1.407 _WPQGAVPQLPPSAPAT(ph)SEMTTTPERPR_
CAD Phosphorylation S1859 -0.178 -0.084 _IHRAS(ph)DPGLPAEEPKEK_
CASP3 Ubiquitylation K11 -0.053 -0.687 _(ac)MENTENSVDSK(gl)SIK_
CASP3 Ubiquitylation K14 -0.455 -0.687 _SIK(gl)NLEPK_
CASP3 Ubiquitylation K57 -0.304 -1.817 _NFHK(gl)STGMTSR_
CASP3 Ubiquitylation K82 -0.268 -0.605 _NLK(gl)YEVR_
CASP8 Ubiquitylation K183 1.917 _IINDYEEFSK(gl)ER_
CASP8 Ubiquitylation K461 -2.031 _NMGK(gl)QMPQPTFTLR_
CSNK1A1 Ubiquitylation K8 -0.342 -0.408 _(ac)ASSSGSK(gl)AEFIVGGK_
CSNK1A1 Ubiquitylation K18 0.772 _AEFIVGGKYK(gl)_
CSNK1A1 Ubiquitylation K225 0.039 0.502 _TSLPWQGLK(gl)AATK_
CSNK1A1 Ubiquitylation K304 -0.489 0.015 _QK(gl)AAQQAASSSGQGQQAQTPTGK_
DAXX Phosphorylation S33 -2.344 -2.634 _(ac)ATANSIIVLDDDDEDEAAAQPGPSHPLPNAAS(ph)PGAEAPSSSEPHGAR_
DAXX Phosphorylation S178 -1.839 -1.808 _KLNLAPAATTSNEPSGNNPPTHLSLDPTNAENTASQS(ph)PR_
DAXX Ubiquitylation K255 1.051 -0.046 _LCELK(gl)DCSSLTGR_
DAXX Ubiquitylation K289 -0.127 _LINK(gl)PGPDTFPDYGDVLR_
DAXX Ubiquitylation K390 0.502 _LDEVISK(gl)YAMLQDK_
DAXX Phosphorylation S495 0.727 0.865 _DGDKS(ph)PMSSLQISNEK_
DAXX Phosphorylation S671 -0.877 -1.038 _ICTLPSPPS(ph)PLASLAPVADSSTR_
DAXX Phosphorylation S675 -0.654 _KICTLPSPPSPLAS(ph)LAPVADSSTR_
DAXX Phosphorylation S688 -0.111 -0.664 _VDS(ph)PSHGLVTSSLCIPSPAR_
DAXX Phosphorylation S690 -0.048 _VDS(ph)PSHGLVTSSLCIPSPAR_
DAXX Phosphorylation S702 -0.432 -0.620 _VDSPSHGLVTSSLCIPS(ph)PAR_
DEDD Ubiquitylation K237 0.372 _FNQANTILK(gl)SR_
DEDD2 Ubiquitylation K193 -2.121 _GAPAAPQQQSEPARPSSEGK(gl)VTCDIR_
DFFA Phosphorylation S28 2.697 2.074 _NYS(ph)REQHGVAASCLEDLR_
DFFA Phosphorylation S37 -0.697 -0.347 _EQHGVAAS(ph)CLEDLR_
DFFA Ubiquitylation K208 -0.111 _EGSLLSK(gl)QEESK_
DFFA Phosphorylation S315 -0.237 -0.360 _AS(ph)PPGDLQNPK_
EGFR Phosphorylation T693 0.486 -0.139 _ELVEPLT(ph)PSGEAPNQALLR_
EGFR Phosphorylation S991 -0.041 _MHLPS(ph)PTDSNFYR_
EPHB2 Ubiquitylation K578 -0.752 -0.618 _QSPEDVYFSK(gl)SEQLKPLK_
EPHB2 Ubiquitylation K583 0.445 0.124 _SEQLK(gl)PLK_
EPHB2 Ubiquitylation K617 0.339 _QK(gl)VIGAGEFGEVYK_
EPHB2 Ubiquitylation K649 -1.219 _TLK(gl)AGYTEK_
EPHB2 Phosphorylation S776 -0.147 -0.171 _FLEDDTS(ph)DPTYTSALGGK_
EPHB2 Phosphorylation S897 0.000 _LPS(ph)TSGSEGVPFR_
EPHB2 Phosphorylation T898 -0.329 0.424 _LPST(ph)SGSEGVPFR_
EZR Ubiquitylation K3 -0.313 -0.251 _PK(gl)PINVR_
EZR Ubiquitylation K79 0.172 -0.032 _ENPLQFK(gl)FR_
EZR Ubiquitylation K139 1.519 0.361 _FGDYNK(gl)EVHK_
EZR Ubiquitylation K162 1.580 0.660 _VMDQHK(gl)LTR_
EZR Ubiquitylation K253 -0.069 _NISFNDK(gl)K_
EZR Ubiquitylation K263 -0.786 _K(gl)APDFVFYAPR_
EZR Ubiquitylation K344 0.598 0.235 _EK(gl)EELMLR_
EZR Ubiquitylation K357 -0.003 _LQDYEEK(gl)TK_
EZR Ubiquitylation K359 0.051 _LQDYEEK(gl)TK_
EZR Ubiquitylation K450 0.393 0.174 _AK(gl)EAQDDLVK_
FAF1 Ubiquitylation K139 -0.732 _QILENELQIPVSK(gl)MLLK_
FAF1 Ubiquitylation K143 -0.325 0.510 _MLLK(gl)GWK_
FAF1 Ubiquitylation K146 0.008 0.988 _GWK(gl)TGDVEDSTVLK_
FAF1 Ubiquitylation K157 -0.570 -0.411 _TGDVEDSTVLK(gl)SLHLPK_
FAF1 Ubiquitylation K221 0.454 0.951 _EYNLNFSGSSTIQEVK(gl)R_
FAF1 Phosphorylation T580 -0.344 _IRT(ph)PSGEFLER_
FAF1 Phosphorylation S582 0.205 0.092 _TPS(ph)GEFLER_
FAS Phosphorylation S236 -0.027 _ENQGS(ph)HESPTLNPETVAINLSDVDLSK_
FAS Phosphorylation S239 0.266 _ENQGSHES(ph)PTLNPETVAINLSDVDLSK_
FAS Ubiquitylation K343 1.126 _IQTIILK(gl)DITSDSENSNFR_
HSPB1 Phosphorylation S82 1.036 0.723 _QLS(ph)SGVSEIR_
HSPB1 Ubiquitylation K198 -1.654 _AQLGGPEAAK(gl)SDETAAK_
MAP2K4 Phosphorylation S80 0.441 _LRTHS(ph)IESSGK_
MAP2K7 Ubiquitylation K9 -1.406 _(ac)AASSLEQK(gl)LSR_
MAP2K7 Ubiquitylation K300 -1.228 _GQIK(gl)LCDFGISGR_
MAP2K7 Ubiquitylation K442 -1.326 _DVMAK(gl)TESPR_
MAP3K1 Phosphorylation S292 0.209 _RAPS(ph)PDGFSPYSPEETNR_
MAP3K1 Phosphorylation S506 1.427 _SHDFYSHELS(ph)SPVDSPSSLR_
MAP3K1 Phosphorylation S507 1.436 _SHDFYSHELSS(ph)PVDSPSSLR_
MAP3K1 Phosphorylation S923 0.127 -0.120 _LSAS(ph)SEDISER_
MAP3K5 Phosphorylation S1066 -1.241 _SISLPVPVLVEDTSSSSEYGSVS(ph)PDTELKVDPFSFK_
MAP3K5 Phosphorylation S1113 -1.408 -0.562 _TLFLGIPDENFEDHSAPPS(ph)PEEK_
MAPK8IP2 Ubiquitylation K674 -0.899 0.671 _DLLGSK(gl)R_
MAPK9 Phosphorylation Y185 3.533 _TACTNFMMTPY(ph)VVTR_
MET Ubiquitylation K962 0.146 _QIK(gl)DLGSELVR_
MET Phosphorylation S988 0.064 _S(ph)VSPTTEM(ox)VSNESVDYR_
MET Phosphorylation S990 0.192 -0.105 _SVS(ph)PTTEM(ox)VSNESVDYR_
MET Phosphorylation T992 0.501 -0.048 _SVSPT(ph)TEMVSNESVDYR_
MET Phosphorylation S997 0.285 _S(ph)VSPTTEMVS(ph)NESVDYR_
NFAT5 Phosphorylation S163 -0.941 _RHTVLYIS(ph)PPPEDLLDNSR_
NFAT5 Phosphorylation S578 1.128 1.267 _KEIS(ph)SPARPCSFEEAM(ox)K_
NFAT5 Phosphorylation S579 1.019 _KEISS(ph)PARPCSFEEAM(ox)K_
NFKB1 Phosphorylation S907 -0.025 0.113 _TTSQAHSLPLS(ph)PASTR_
NFKB2 Ubiquitylation K741 -2.393 _GHTPLDLTCSTK(gl)VK_
NFKB2 Ubiquitylation K743 -0.624 _GHTPLDLTCSTKVK(gl)_
NFKBIE Ubiquitylation K316 -0.248 _ALVLK(gl)GASR_
PARP1 Phosphorylation S41 -0.803 _MAIMVQS(ph)PMFDGK_
PARP1 Ubiquitylation K84 1.223 _WDDQQK(gl)VK_
PARP1 Ubiquitylation K86 1.058 _VK(gl)KTAEAGGVTGK_
PARP1 Ubiquitylation K87 1.058 _VK(gl)KTAEAGGVTGK_
PARP1 Ubiquitylation K97 1.386 0.406 _TAEAGGVTGK(gl)GQDGIGSK_
PARP1 Ubiquitylation K105 0.828 _GQDGIGSK(gl)AEK_
PARP1 Ubiquitylation K108 1.317 _GQDGIGSKAEK(gl)_
PARP1 Ubiquitylation K119 1.569 _TLGDFAAEYAK(gl)SNR_
PARP1 Ubiquitylation K131 1.025 1.620 _GCMEK(gl)IEK_
PARP1 Ubiquitylation K197 0.445 1.157 _K(gl)QLPGVK_
PARP1 Ubiquitylation K254 0.589 _AQNDLIWNIKDELKK(gl)_
PARP1 Ubiquitylation K262 0.456 _VCSTNDLK(gl)ELLIFNK_
PARP1 Ubiquitylation K320 1.464 1.034 _SDAYYCTGDVTAWTK(gl)CMVK_
PARP1 Ubiquitylation K331 -0.425 -0.480 _TQTPNRK(gl)EWVTPK_
PARP1 Ubiquitylation K337 0.462 0.332 _EWVTPK(gl)EFR_
PARP1 Ubiquitylation K346 0.370 0.411 _EISYLK(gl)K_
PARP1 Phosphorylation T368 -1.474 -1.410 _IFPPETSASVAAT(ph)PPPSTASAPAAVNSSASADKPLSNM(ox)K_
PARP1 Ubiquitylation K400 0.844 1.095 _ILTLGK(gl)LSR_
PARP1 Ubiquitylation K414 1.227 1.241 _AMIEK(gl)LGGK_
PARP1 Ubiquitylation K418 1.131 _LGGK(gl)LTGTANK_
PARP1 Ubiquitylation K425 0.912 0.815 _LTGTANK(gl)ASLCISTKK_
PARP1 Ubiquitylation K433 0.942 _ASLCISTK(gl)K_
PARP1 Ubiquitylation K434 0.020 _ASLCISTKK(gl)_
PARP1 Ubiquitylation K447 1.480 _MEEVK(gl)EANIR_
PARP1 Ubiquitylation K518 0.108 _GQVKEEGINK(gl)SEK_
PARP1 Ubiquitylation K521 0.630 _GQVKEEGINKSEK(gl)R_
PARP1 Ubiquitylation K548 0.125 -0.480 _GGAAVDPDSGLEHSAHVLEK(gl)GGK_
PARP1 Ubiquitylation K551 0.492 -0.573 _GGAAVDPDSGLEHSAHVLEKGGK(gl)_
PARP1 Ubiquitylation K629 1.632 _TGNAWHSK(gl)NFTK_
PARP1 Ubiquitylation K633 0.964 0.091 _NFTK(gl)YPK_
PARP1 Ubiquitylation K654 -0.086 _K(gl)LTVNPGTK_
PARP1 Ubiquitylation K662 0.112 _LTVNPGTK(gl)SK_
PARP1 Ubiquitylation K664 -0.042 -0.111 _LTVNPGTKSK(gl)_
PARP1 Ubiquitylation K683 0.983 1.355 _MIFDVESM(ox)K(gl)K_
PARP1 Ubiquitylation K684 1.213 1.355 _MIFDVESMKK(gl)_
PARP1 Ubiquitylation K700 0.448 _MPLGK(gl)LSK_
PARP1 Phosphorylation S782 0.648 0.490 _GGS(ph)DDSSKDPIDVNYEK_
PARP1 Ubiquitylation K949 0.738 _HSVK(gl)GLGK_
PFN1 Ubiquitylation K54 -0.190 0.319 _TFVNITPAEVGVLVGK(gl)DR_
PFN1 Ubiquitylation K70 0.186 0.451 _SSFYVNGLTLGGQK(gl)CSVIR_
PFN1 Ubiquitylation K91 -0.513 -0.205 _TK(gl)STGGAPTFNVTVTK_
PFN1 Ubiquitylation K105 0.309 -0.352 _STGGAPTFNVTVTK(gl)TDK_
PFN1 Ubiquitylation K108 0.414 -0.098 _TDK(gl)TLVLLMGK_
PFN1 Ubiquitylation K126 0.640 0.539 _EGVHGGLINK(gl)K_
PFN1 Ubiquitylation K127 0.582 0.353 _EGVHGGLINKK(gl)_
PFN2 Ubiquitylation K91 -0.195 -0.320 _TK(gl)SQGGEPTYNVAVGR_
PFN2 Ubiquitylation K126 0.388 1.109 _EGVHGGGLNK(gl)K_
PTPN13 Phosphorylation S345 0.424 0.250 _YS(ph)DGSIALDIFGPQK_
PTPN13 Phosphorylation S890 0.482 -0.006 _S(ph)LNLQAESVR_
PTPN13 Phosphorylation S908 0.526 0.303 _AIS(ph)TGSLASSTLNK_
PTPN13 Phosphorylation S936 0.498 0.321 _RLS(ph)CSELSLYQPLQNSSK_
PTPN13 Phosphorylation S938 0.489 0.032 _LSCS(ph)ELSLYQPLQNSSK_
PTPN13 Phosphorylation S1029 0.693 0.332 _SVAS(ph)LNRSPER_
PTPN13 Phosphorylation S1033 0.266 0.445 _SVASLNRS(ph)PERR_
PTPN13 Phosphorylation S1358 -0.423 -0.259 _TFSS(ph)SPPKPGDIFEVELAK_
PTPN13 Phosphorylation S1359 -0.207 -0.067 _TFSSS(ph)PPKPGDIFEVELAK_
PTPN13 Phosphorylation S1629 0.646 0.399 _DSSQPSCVEQSTS(ph)SDENEMSDK_
PTPN13 Phosphorylation S1630 0.306 0.272 _DSSQPSCVEQSTSS(ph)DENEM(ox)SDK_
PTPN13 Phosphorylation S2032 -0.758 -0.522 _GS(ph)PNLTLPK_
PTPN13 Phosphorylation S2107 0.703 _TEDTDCDGS(ph)PLPEYFTEATK_
RALBP1 Phosphorylation S10 -0.478 _(ac)TECFLPPTS(ph)SPSEHR_
RALBP1 Phosphorylation S11 -0.587 -0.381 _(ac)TECFLPPTSS(ph)PSEHRR_
RALBP1 Phosphorylation S13 -0.465 _(ac)TECFLPPTSSPS(ph)EHR_
RALBP1 Phosphorylation S29 -0.625 -1.152 _TPS(ph)SEEISPTK_
RALBP1 Phosphorylation S30 -1.015 _TPSS(ph)EEISPTKFPGLYR_
RALBP1 Phosphorylation S645 -0.718 -0.600 _AGKEPAKPS(ph)PSR_
RIPK1 Ubiquitylation K642 -0.431 _EGIK(gl)GATVGK_
ROCK1 Phosphorylation S1105 -0.245 -0.845 _LLDLSDSTSVAS(ph)FPSADETDGNLPESR_
TONSL Ubiquitylation K336 -1.432 _AAEAYQK(gl)QLR_
TONSL Phosphorylation S719 -0.359 -0.212 _VS(ph)PGQAAPAMARPR_
TP53 Ubiquitylation K120 -0.188 _LGFLHSGTAK(gl)SVTCTYSPALNK_
TP53 Ubiquitylation K164 0.157 -1.260 _AMAIYK(gl)QSQHMTEVVR_
TP53 Phosphorylation S314 -0.695 -1.000 _ALPNNTSS(ph)SPQPK_
TP53 Phosphorylation S315 -0.762 -0.959 _RALPNNTSSS(ph)PQPK_
TP53 Ubiquitylation K320 -0.978 _ALPNNTSSSPQPKK(gl)_
TP53 Ubiquitylation K357 -0.231 -0.823 _ELNEALELKDAQAGK(gl)EPGGSR_
TPX2 Phosphorylation T72 -1.259 _ANLQQAIVT(ph)PLKPVDNTYYK_
TPX2 Phosphorylation T405 -2.166 _DPQT(ph)PVLQTK_
TPX2 Ubiquitylation K640 -0.320 0.644 _GALK(gl)AQTWK_
TPX2 Ubiquitylation K763 -0.340 _YQGLEIK(gl)SSDQPLTVPVSPK_
TPX2 Phosphorylation T770 -1.331 _SSDQPLT(ph)VPVSPK_
TPX2 Phosphorylation S774 -1.173 -0.922 _SSDQPLTVPVS(ph)PK_
TRAF2 Phosphorylation T7 -0.822 -1.190 _(ac)AAASVT(ph)PPGSLELLQPGFSK_
TRAF2 Ubiquitylation K27 -0.253 2.194 _TLLGTK(gl)LEAK_
TRAF2 Ubiquitylation K119 0.519 _GTLK(gl)EYESCHEGR_
TRAF2 Ubiquitylation K176 -1.233 1.022 _APCCGADVK(gl)AHHEVCPK_
TRAF2 Ubiquitylation K207 0.147 0.918 _FQDHVK(gl)TCGK_
TRAF2 Ubiquitylation K481 -0.507 0.417 _MEAK(gl)NSYVR_
TUFM Ubiquitylation K48 -0.221 _GLAVEAK(gl)K_
TUFM Ubiquitylation K49 -0.221 _GLAVEAK(gl)K_
XIAP Ubiquitylation K31 -0.312 -0.651 _LK(gl)TFANFPSGSPVSASTLAR_
XIAP Ubiquitylation K208 -0.788 -0.846 _LK(gl)NWEPCDR_
XIAP Ubiquitylation K358 -0.720 0.047 _TTEK(gl)TPSLTR_


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