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Query: ALG2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
ALG2 0 0.262 0.490 -0.760 0.103 0.159

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence

Background Information for ALG2:


Pubmed-ALG2 »
Uniprot-ALG2 »
Biogrid-ALG2 »
ProteomicsDB-ALG2 »

Tumorportal-ALG2 »
COSMIC-ALG2 »
GenomeRNAi-ALG2 »
Genecards-ALG2


Protein-protein Interactions for ALG2
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CD79B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HMOX2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TGOLN2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in ALG2
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Glyco_trans_1 IPR001296 0


Protein complexes (CORUM database) featuring ALG2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring ALG2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members Pathway Pathway_11 REACTOME_METABOLISM_OF_PROTEINS 0 12.01
Category members GO Category GO:0044267 cellular protein metabolic process Database 10.42
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members GO Category GO:0047485 protein N-terminus binding Database 1.84
Category members GO Category GO:0005789 endoplasmic reticulum membrane Database 1.57
Category members GO Category GO:0016020 membrane Database 0.52
Category members GO Category GO:0048471 perinuclear region of cytoplasm Database 0.39
Category members GO Category GO:0046982 protein heterodimerization activity Database 0.28
Category members GO Category GO:0006488 dolichol-linked oligosaccharide biosynthetic process Database 0.28
Category members Pathway Pathway_93 REACTOME_BIOSYNTHESIS_OF_THE_N_GLYCAN_PRECURSOR_DOLICHOL_LIPID_LINKED_OLIGOSACCHARIDE_LLO_AND_TRANSFER_TO_A_NASCENT_PROTEIN 0 0.18
Category members GO Category GO:0048306 calcium-dependent protein binding Database 0.17
Category members GO Category GO:0009058 biosynthetic process Database 0.11
Category members Pathway Pathway_109 KEGG_N_GLYCAN_BIOSYNTHESIS 0 0.04
Category members Pathway Pathway_386 ST_FAS_SIGNALING_PATHWAY 0 0.02
Category members Pathway Pathway_94 REACTOME_POST_TRANSLATIONAL_PROTEIN_MODIFICATION 0 0
Category members Pathway Pathway_95 REACTOME_ASPARAGINE_N_LINKED_GLYCOSYLATION 0 0
Category members Disease phenotype Congenital_myasthenic_syndromes_with_glycosylation_defect Congenital myasthenic syndromes with glycosylation defect Database 0
Category members GO Category GO:0000033 alpha-1,3-mannosyltransferase activity Database 0
Category members GO Category GO:0018279 protein N-linked glycosylation via asparagine Database 0
Category members GO Category GO:0043495 protein anchor Database 0
Category members GO Category GO:0043687 post-translational protein modification Database 0
Category members GO Category GO:0051592 response to calcium ion Database 0


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