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Query: DFFA

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
DFFA 2 4.440 -0.290 -0.220

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
DFFA Phosphorylation S28 2.697 2.074 _NYS(ph)REQHGVAASCLEDLR_
DFFA Phosphorylation S37 -0.697 -0.347 _EQHGVAAS(ph)CLEDLR_
DFFA Phosphorylation S315 -0.237 -0.360 _AS(ph)PPGDLQNPK_
DFFA Ubiquitylation K208 -0.111 _EGSLLSK(gl)QEESK_

Background Information for DFFA:


Pubmed-DFFA »
Uniprot-DFFA »
Biogrid-DFFA »
ProteomicsDB-DFFA »

Tumorportal-DFFA »
COSMIC-DFFA »
GenomeRNAi-DFFA »
Genecards-DFFA


Protein-protein Interactions for DFFA
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait DFFA Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in DFFA
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Death_domain IPR000488 0.08
Category members CIDE-N_dom IPR003508 0


Protein complexes (CORUM database) featuring DFFA
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring DFFA
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005654 nucleoplasm Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0006921 cellular component disassembly involved in execution phase of apoptosis Database 2.98
Category members Pathway Pathway_876 REACTOME_APOPTOTIC_EXECUTION_PHASE 0 2.5
Category members Pathway Pathway_837 REACTOME_APOPTOSIS 0 2.39
Category members GO Category GO:0006915 apoptotic process Database 2.12
Category members Pathway Pathway_962 BIOCARTA_FAS_PATHWAY 0 1.75
Category members Pathway Pathway_956 BIOCARTA_DNAFRAGMENT_PATHWAY 0 0.62
Category members Pathway Pathway_955 REACTOME_APOPTOSIS_INDUCED_DNA_FRAGMENTATION 0 0.51
Category members GO Category GO:0000790 nuclear chromatin Database 0.46
Category members Pathway Pathway_963 BIOCARTA_TNFR1_PATHWAY 0 0.44
Category members GO Category GO:0005622 intracellular Database 0.32
Category members GO Category GO:0006309 apoptotic DNA fragmentation Database 0.26
Category members GO Category GO:0043065 positive regulation of apoptotic process Database 0.26
Category members Pathway Pathway_961 PID_CASPASE_PATHWAY 0 0.19
Category members Pathway Pathway_960 BIOCARTA_HIVNEF_PATHWAY 0 0.17
Category members Pathway Pathway_1015 PID_HIV_NEF_PATHWAY 0 0.15
Category members GO Category GO:0070242 thymocyte apoptotic process Database 0.13
Category members Pathway Pathway_291 BIOCARTA_SET_PATHWAY 0 0.04
Category members Pathway Pathway_386 ST_FAS_SIGNALING_PATHWAY 0 0.02
Category members Pathway Pathway_965 BIOCARTA_CASPASE_PATHWAY 0 0.01
Category members Pathway Pathway_1012 BIOCARTA_MITOCHONDRIA_PATHWAY 0 0
Category members Pathway Pathway_1020 BIOCARTA_DEATH_PATHWAY 0 0
Category members Pathway Pathway_572 KEGG_APOPTOSIS 0 0
Category members Pathway Pathway_959 SA_CASPASE_CASCADE 0 0
Category members GO Category GO:0004536 deoxyribonuclease activity Database 0
Category members GO Category GO:0007165 signal transduction Database 0
Category members GO Category GO:0035556 intracellular signal transduction Database 0


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