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Query: PFN2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
PFN2 0 3.508 -0.250 -0.070
PFN2 0 3.508 -0.250 -0.070 0.715 1.366

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
PFN2 Ubiquitylation K126 0.388 1.109 _EGVHGGGLNK(gl)K_
PFN2 Ubiquitylation K91 -0.195 -0.320 _TK(gl)SQGGEPTYNVAVGR_

Background Information for PFN2:


Pubmed-PFN2 »
Uniprot-PFN2 »
Biogrid-PFN2 »
ProteomicsDB-PFN2 »

Tumorportal-PFN2 »
COSMIC-PFN2 »
GenomeRNAi-PFN2 »
Genecards-PFN2


Protein-protein Interactions for PFN2
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait PFN2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in PFN2
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Profilin_chordates IPR005454 0.08
Category members Profilin_eukaryotes/bac IPR005455 0


Protein complexes (CORUM database) featuring PFN2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 2300 Profilin 2 complex Database 0


Categories featuring PFN2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0003779 actin binding Database 5.41
Category members GO Category GO:0015629 actin cytoskeleton Database 2.22
Category members GO Category GO:0030036 actin cytoskeleton organization Database 1.08
Category members Pathway Pathway_673 REACTOME_AXON_GUIDANCE 0 1.06
Category members Pathway Pathway_838 SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES 0 0.35
Category members Pathway Pathway_42 REACTOME_DEVELOPMENTAL_BIOLOGY 0 0.32
Category members GO Category GO:0030838 positive regulation of actin filament polymerization Database 0.21
Category members GO Category GO:0030837 negative regulation of actin filament polymerization Database 0.13
Category members Pathway Pathway_580 KEGG_REGULATION_OF_ACTIN_CYTOSKELETON 0 0.08
Category members Pathway Pathway_386 ST_FAS_SIGNALING_PATHWAY 0 0.02
Category members Pathway Pathway_1031 REACTOME_SIGNALING_BY_ROBO_RECEPTOR 0 0
Category members GO Category GO:0043195 terminal bouton Database 0


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