RNAi screen result	RNAPII IP (MG132)	CSB IP	CSB IP (MG132)	Chrom.	Chrom. (MG132)	Ubi /Phospo	Ubi /Phospho (MG132)
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Gene name	MGoogle Score	RNAi high	RNAi low	RNAPII-IP (MG132)	CSB-IP	CSB-IP (MG132)	Chrom.	Chrom. (MG132)
GDI1	1	-1.240	2.790	-0.675	-0.337	-0.291	0.493	-1.831
PFN1	1	-0.430	-0.180	0.002	2.497	-0.084	0.348	-0.059
VASP	1	0.180	0.270				1.849
CFL1	1			0.725	0.148	-0.943
GDI2	0	-0.180	-0.020	-0.675	-0.337	-0.291	0.493	-1.831
MYLK	0	-0.520	0.000	0.754
ROCK1	0	-1.420	2.380		-0.112	-0.732
PFN2	0	-0.250	-0.070				0.715	1.366
PFN2	0	-0.250	-0.070
CDC42	0	-0.170	0.490	-0.597			-1.527	-1.013
CDC42	0	1.240	-0.940	-0.597			-1.527	-1.013
FSCN1	0	0.880	-0.810	0.725			0.430	0.568
WASL	0	-0.430	0.380
ACTR3	0	1.800	-1.060	0.313	-0.076	0.489	-0.053	-0.011
FLNC	0	0.570	0.010	-0.219		-0.558	0.899	0.710
PAK4	0	-0.700	0.980				0.206	-0.937
ROCK2	0	-1.660	2.330
ACTR2	0	0.040	-0.230		-0.421		0.492	-0.525
ACTR2	0	0.330	0.020		-0.421		0.492	-0.525
ACTR2	0	0.040	-0.230	-0.073
ACTR2	0	0.330	0.020	-0.073
AKT1	0	-0.050	0.700
AKT1	0	0.860	-0.040
PAK1	0	1.190	-0.630
ACTG2	0	-1.000	0.580		-0.189	0.025	-0.002	-0.165
ACTG2	0	-1.000	0.580	0.157
CFL2	0	-0.750	1.060		0.658		1.248
PAK2	0	-0.760	1.040

Gene name	PTM type	PTM site	UV	UV (MG132)	Sequence
ACTR2	Ubiquitylation	K46	-0.195	-0.572	_STTK(gl)VGNIEIK_
ACTR2	Ubiquitylation	K53	-0.157		_VGNIEIK(gl)DLMVGDEASELR_
ACTR2	Ubiquitylation	K106		-2.562	_NCK(gl)ILLTEPPMNPTK_
ACTR2	Ubiquitylation	K118	-1.305	-2.424	_ILLTEPPMNPTK(gl)NR_
ACTR2	Ubiquitylation	K253		-1.504	_IIK(gl)VGGER_
ACTR2	Ubiquitylation	K322	0.791	-0.441	_ELK(gl)QLYLER_
ACTR2	Ubiquitylation	K331	0.083	-0.829	_VLK(gl)GDVEK_
ACTR2	Ubiquitylation	K336	0.177	-0.230	_GDVEK(gl)LSK_
ACTR2	Ubiquitylation	K381		-1.848	_QEYQEK(gl)GVR_
ACTR3	Ubiquitylation	K225	-1.054	-1.094	_DREVGIPPEQSLETAK(gl)AVK_
ACTR3	Ubiquitylation	K251	-1.416		_EFNKYDTDGSK(gl)WIK_
ACTR3	Ubiquitylation	K264	-0.776		_QYTGINAISK(gl)K_
ACTR3	Ubiquitylation	K265		-0.295	_QYTGINAISKK(gl)_
ACTR3	Ubiquitylation	K348	0.619	0.713	_LK(gl)LSEELSGGR_
AKT1	Phosphorylation	S124	0.252	0.311	_SGS(ph)PSDNSGAEEMEVSLAKPK_
AKT1	Phosphorylation	S126	-0.241		_SGSPS(ph)DNSGAEEM(ox)EVSLAK_
AKT1	Ubiquitylation	K301	0.988		_EGIK(gl)DGATMK_
CDC42	Ubiquitylation	K173	-1.839		_DDPSTIEK(gl)LAK_
CDC42	Ubiquitylation	K178	-0.801	-0.716	_NK(gl)QKPITPETAEK_
CDC42	Ubiquitylation	K180	-1.806		_QK(gl)PITPETAEK(gl)LAR_
CDC42	Ubiquitylation	K189	-1.082		_QKPITPETAEK(gl)LAR_
CDC42	Ubiquitylation	K198	0.550	1.159	_AVK(gl)YVECSALTQK_
CDC42	Ubiquitylation	K208	-0.937	0.038	_YVECSALTQK(gl)GLK_
CDC42	Ubiquitylation	K228	-2.488		_NVFDEAILAALEPPEPK(gl)K_
CDC42	Ubiquitylation	K229	-1.254		_NVFDEAILAALEPPEPKK(gl)_
CFL1	Phosphorylation	S41	0.781	0.338	_(ac)AS(ph)GVAVSDGVIK_
CFL1	Ubiquitylation	K57	0.538	0.318	_VFNDMK(gl)VR_
CFL1	Ubiquitylation	K82	1.563		_AVLFCLSEDK(gl)K_
CFL1	Ubiquitylation	K83	1.163		_AVLFCLSEDKK(gl)_
CFL1	Ubiquitylation	K116	0.583		_MLPDK(gl)DCR_
CFL1	Ubiquitylation	K130	0.398	0.825	_YALYDATYETK(gl)ESK_
CFL1	Ubiquitylation	K133	0.441		_YALYDATYETKESK(gl)_
CFL1	Ubiquitylation	K152	0.783	0.508	_SK(gl)MIYASSK_
CFL1	Ubiquitylation	K159	0.778	0.532	_MIYASSK(gl)DAIK_
CFL1	Ubiquitylation	K182	-0.079	0.077	_HELQANCYEEVK(gl)DR_
CFL2	Phosphorylation	S3	0.851	-0.223	_(ac)AS(ph)GVTVNDEVIK_
FLNC	Phosphorylation	S2233	0.713	0.170	_LGS(ph)FGSITR_
FSCN1	Ubiquitylation	K81	0.201	0.471	_YLAADK(gl)DGNVTCER_
FSCN1	Ubiquitylation	K406	-0.989		_K(gl)VTGTLDANR_
GDI1	Ubiquitylation	K58	-0.561	-0.548	_NPYYGGESASITPLEDLYK(gl)R_
GDI1	Phosphorylation	S65	-0.852	-0.729	_IPGS(ph)PPESMGR_
GDI1	Ubiquitylation	K214	0.003	0.067	_IK(gl)LYSESLAR_
GDI1	Ubiquitylation	K273	-0.488	0.081	_VIGVK(gl)SEGEIAR_
GDI1	Ubiquitylation	K439	0.483	0.420	_MTGSEFDFEEMK(gl)R_
GDI2	Ubiquitylation	K58	-0.561	-0.548	_NPYYGGESASITPLEDLYK(gl)R_
GDI2	Phosphorylation	S65	-0.852	-0.729	_IPGS(ph)PPESMGR_
GDI2	Ubiquitylation	K214	0.003	0.067	_IK(gl)LYSESLAR_
GDI2	Ubiquitylation	K273	-0.488	0.081	_VIGVK(gl)SEGEIAR_
GDI2	Ubiquitylation	K439	0.483	0.420	_MTGSEFDFEEMK(gl)R_
PAK1	Phosphorylation	S174	-1.439	-0.597	_AVSETPAVPPVS(ph)EDEDDDDDDATPPPVIAPRPEHTK_
PAK1	Phosphorylation	T212		0.312	_SVIEPLPVT(ph)PTR_
PAK1	Phosphorylation	T219	-0.560	-0.962	_DVAT(ph)SPISPTENNTT(ph)PPDALTR_
PAK1	Phosphorylation	S220	-0.916	-0.774	_DVATS(ph)PISPTENNTTPPDALTR_
PAK1	Phosphorylation	S223	1.033	0.153	_DVATSPIS(ph)PTENNTTPPDALTR_
PAK1	Phosphorylation	T225	-1.278		_DVATSPISPT(ph)ENNTTPPDALTR_
PAK1	Phosphorylation	T230	-1.418	-1.502	_DVATSPISPTENNTT(ph)PPDALTR_
PAK2	Phosphorylation	S2	-1.228	-0.902	_(ac)S(ph)DNGELEDKPPAPPVR_
PAK2	Ubiquitylation	K136	1.213		_FYDSNTVK(gl)QK_
PAK2	Phosphorylation	S141	-0.294	-0.321	_YLS(ph)FTPPEK_
PAK2	Ubiquitylation	K370	-0.565		_DIK(gl)SDNVLLGMEGSVK_
PAK4	Phosphorylation	S104	-0.563	-0.422	_RDS(ph)PPPPAR_
PAK4	Phosphorylation	S181	-0.528	-0.724	_DKRPLS(ph)GPDVGTPQPAGLASGAK_
PAK4	Phosphorylation	T207	-0.287	-0.118	_LAAGRPFNT(ph)YPR_
PAK4	Phosphorylation	S291		-3.268	_GAPSPGVLGPHASEPQLAPPACTPAAPAVPGPPGPRS(ph)PQREPQR_
PAK4	Phosphorylation	S474	-0.003	0.050	_S(ph)LVGTPYWMAPELISR_
PAK4	Phosphorylation	T478	0.024		_RKSLVGT(ph)PYWM(ox)APELISR_
PFN1	Ubiquitylation	K54	-0.190	0.319	_TFVNITPAEVGVLVGK(gl)DR_
PFN1	Ubiquitylation	K70	0.186	0.451	_SSFYVNGLTLGGQK(gl)CSVIR_
PFN1	Ubiquitylation	K91	-0.513	-0.205	_TK(gl)STGGAPTFNVTVTK_
PFN1	Ubiquitylation	K105	0.309	-0.352	_STGGAPTFNVTVTK(gl)TDK_
PFN1	Ubiquitylation	K108	0.414	-0.098	_TDK(gl)TLVLLMGK_
PFN1	Ubiquitylation	K126	0.640	0.539	_EGVHGGLINK(gl)K_
PFN1	Ubiquitylation	K127	0.582	0.353	_EGVHGGLINKK(gl)_
PFN2	Ubiquitylation	K91	-0.195	-0.320	_TK(gl)SQGGEPTYNVAVGR_
PFN2	Ubiquitylation	K126	0.388	1.109	_EGVHGGGLNK(gl)K_
ROCK1	Phosphorylation	S1105	-0.245	-0.845	_LLDLSDSTSVAS(ph)FPSADETDGNLPESR_
ROCK2	Ubiquitylation	K1222	-0.679		_ADAK(gl)EIPR_
VASP	Phosphorylation	S239	0.625	-0.774	_VS(ph)KQEEASGGPTAPK_
WASL	Phosphorylation	S430	0.399	0.664	_VEQNSRPVS(ph)CSGR_
WASL	Phosphorylation	S432		1.141	_VEQNSRPVSCS(ph)GR_