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Query: ACTR2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
ACTR2 0 0.034 0.040 -0.230 -0.421 0.492 -0.525
ACTR2 0 0.034 0.040 -0.230 -0.073
ACTR2 0 0.034 0.330 0.020 -0.421 0.492 -0.525
ACTR2 0 0.034 0.330 0.020 -0.073

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
ACTR2 Ubiquitylation K336 0.177 -0.230 _GDVEK(gl)LSK_
ACTR2 Ubiquitylation K322 0.791 -0.441 _ELK(gl)QLYLER_
ACTR2 Ubiquitylation K46 -0.195 -0.572 _STTK(gl)VGNIEIK_
ACTR2 Ubiquitylation K331 0.083 -0.829 _VLK(gl)GDVEK_
ACTR2 Ubiquitylation K253 -1.504 _IIK(gl)VGGER_
ACTR2 Ubiquitylation K381 -1.848 _QEYQEK(gl)GVR_
ACTR2 Ubiquitylation K118 -1.305 -2.424 _ILLTEPPMNPTK(gl)NR_
ACTR2 Ubiquitylation K106 -2.562 _NCK(gl)ILLTEPPMNPTK_
ACTR2 Ubiquitylation K53 -0.157 _VGNIEIK(gl)DLMVGDEASELR_

Background Information for ACTR2:


Pubmed-ACTR2 »
Uniprot-ACTR2 »
Biogrid-ACTR2 »
ProteomicsDB-ACTR2 »

Tumorportal-ACTR2 »
COSMIC-ACTR2 »
GenomeRNAi-ACTR2 »
Genecards-ACTR2


Protein-protein Interactions for ACTR2
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ACTB Cat. description Hein, Mann, Cell 2015
Category members IP bait ACTR2 Cat. description Hein, Mann, Cell 2015
Category members IP bait ANLN Cat. description Hein, Mann, Cell 2015
Category members IP bait ATP6AP2 Cat. description Hein, Mann, Cell 2015
Category members IP bait CAPZA2 Cat. description Hein, Mann, Cell 2015
Category members IP bait CCT2 Cat. description Hein, Mann, Cell 2015
Category members IP bait CCT3 Cat. description Hein, Mann, Cell 2015
Category members IP bait CCT4 Cat. description Hein, Mann, Cell 2015
Category members IP bait CCT7 Cat. description Hein, Mann, Cell 2015
Category members IP bait CCT8 Cat. description Hein, Mann, Cell 2015
Category members IP bait CORO1C Cat. description Hein, Mann, Cell 2015
Category members IP bait DBN1 Cat. description Hein, Mann, Cell 2015
Category members IP bait FLNA Cat. description Hein, Mann, Cell 2015
Category members IP bait FLOT1 Cat. description Hein, Mann, Cell 2015
Category members IP bait IQGAP1 Cat. description Hein, Mann, Cell 2015
Category members IP bait ITGA5 Cat. description Hein, Mann, Cell 2015
Category members IP bait LIMA1 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYH10 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYH9 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYO18A Cat. description Hein, Mann, Cell 2015
Category members IP bait MYO19 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYO1C Cat. description Hein, Mann, Cell 2015
Category members IP bait MYO5C Cat. description Hein, Mann, Cell 2015
Category members IP bait PPP1CB Cat. description Hein, Mann, Cell 2015
Category members IP bait SYNPO Cat. description Hein, Mann, Cell 2015
Category members IP bait TMOD3 Cat. description Hein, Mann, Cell 2015
Category members IP bait TPM1 Cat. description Hein, Mann, Cell 2015
Category members IP bait ACTR3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ACTR3B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ARPC1A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ARPC1B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ARPC3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in ACTR2
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Actin-related IPR004000 0.11


Protein complexes (CORUM database) featuring ACTR2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 27 Arp2/3 protein complex Database 0.04


Categories featuring ACTR2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members GO Category GO:0003779 actin binding Database 5.41
Category members GO Category GO:0005938 cell cortex Database 2.26
Category members GO Category GO:0015629 actin cytoskeleton Database 2.22
Category members Pathway Pathway_579 PID_ERBB1_DOWNSTREAM_PATHWAY 0 1.97
Category members Pathway Pathway_309 ST_INTEGRIN_SIGNALING_PATHWAY 0 1.35
Category members Pathway Pathway_561 PID_PDGFRB_PATHWAY 0 1.18
Category members GO Category GO:0007163 establishment or maintenance of cell polarity Database 1.08
Category members GO Category GO:0030036 actin cytoskeleton organization Database 1.08
Category members Pathway Pathway_669 PID_RAC1_PATHWAY 0 0.68
Category members Pathway Pathway_568 PID_CDC42_PATHWAY 0 0.68
Category members Pathway Pathway_838 SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES 0 0.35
Category members GO Category GO:0038096 Fc-gamma receptor signaling pathway involved in phagocytosis Database 0.33
Category members Pathway Pathway_667 BIOCARTA_RHO_PATHWAY 0 0.3
Category members GO Category GO:0016482 cytoplasmic transport Database 0.29
Category members Pathway Pathway_510 SIG_CHEMOTAXIS 0 0.28
Category members GO Category GO:0006928 cellular component movement Database 0.24
Category members GO Category GO:0051321 meiotic cell cycle Database 0.23
Category members Pathway Pathway_615 BIOCARTA_CDC42RAC_PATHWAY 0 0.18
Category members Pathway Pathway_236 BIOCARTA_MPR_PATHWAY 0 0.06
Category members GO Category GO:0008356 asymmetric cell division Database 0.05
Category members GO Category GO:0045087 innate immune response Database 0.05
Category members GO Category GO:0034314 Arp2/3 complex-mediated actin nucleation Database 0.01
Category members Pathway Pathway_1037 BIOCARTA_SALMONELLA_PATHWAY 0 0
Category members Pathway Pathway_912 BIOCARTA_ACTINY_PATHWAY 0 0
Category members GO Category GO:0005885 Arp2/3 protein complex Database 0
Category members GO Category GO:0030478 actin cap Database 0
Category members GO Category GO:0033206 meiotic cytokinesis Database 0
Category members GO Category GO:0042995 cell projection Database 0
Category members GO Category GO:0051653 spindle localization Database 0


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