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Query: FLNC

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
FLNC 0 1.715 0.570 0.010 -0.219 -0.558 0.899 0.710

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
FLNC Phosphorylation S2233 0.713 0.170 _LGS(ph)FGSITR_

Background Information for FLNC:


Pubmed-FLNC »
Uniprot-FLNC »
Biogrid-FLNC »
ProteomicsDB-FLNC »

Tumorportal-FLNC »
COSMIC-FLNC »
GenomeRNAi-FLNC »
Genecards-FLNC


Protein-protein Interactions for FLNC
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait C6orf141 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ERI2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FRYL Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GNG3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HSPB7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait KCTD13 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MFN1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NT5C Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NUAK2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait OFCC1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PAX4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PLEKHO1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PSMC4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RAB8B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RAPGEF5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SMOX Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TNFAIP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in FLNC
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members CH-domain IPR001715 0.63
Category members Filamin/ABP280_rpt IPR001298 0.02
Category members Filamin/ABP280_repeat-like IPR017868 0
Category members Ig_E-set IPR014756 0


Protein complexes (CORUM database) featuring FLNC
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring FLNC
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0003779 actin binding Database 5.41
Category members GO Category GO:0043034 costamere Database 1.42
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members Pathway Pathway_595 KEGG_FOCAL_ADHESION 0 1.08
Category members GO Category GO:0005856 cytoskeleton Database 0.63
Category members GO Category GO:0008092 cytoskeletal protein binding Database 0.5
Category members GO Category GO:0042383 sarcolemma Database 0.36
Category members Pathway Pathway_838 SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES 0 0.35
Category members GO Category GO:0030018 Z disc Database 0.32
Category members GO Category GO:0034329 cell junction assembly Database 0.29
Category members Pathway Pathway_560 REACTOME_CELL_CELL_COMMUNICATION 0 0.25
Category members Pathway Pathway_923 REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS 0 0.18
Category members Pathway Pathway_715 KEGG_MAPK_SIGNALING_PATHWAY 0 0
Category members Pathway Pathway_925 REACTOME_CELL_JUNCTION_ORGANIZATION 0 0
Category members GO Category GO:0016528 sarcoplasm Database 0
Category members GO Category GO:0030506 ankyrin binding Database 0
Category members GO Category GO:0048747 muscle fiber development Database 0


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