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Query: FSCN1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
FSCN1 0 2.395 0.880 -0.810 0.725 0.430 0.568

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
FSCN1 Ubiquitylation K81 0.201 0.471 _YLAADK(gl)DGNVTCER_
FSCN1 Ubiquitylation K406 -0.989 _K(gl)VTGTLDANR_

Background Information for FSCN1:


Pubmed-FSCN1 »
Uniprot-FSCN1 »
Biogrid-FSCN1 »
ProteomicsDB-FSCN1 »

Tumorportal-FSCN1 »
COSMIC-FSCN1 »
GenomeRNAi-FSCN1 »
Genecards-FSCN1


Protein-protein Interactions for FSCN1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ANLN Cat. description Hein, Mann, Cell 2015
Category members IP bait BMPR1A Cat. description Hein, Mann, Cell 2015
Category members IP bait CALML3 Cat. description Hein, Mann, Cell 2015
Category members IP bait DBN1 Cat. description Hein, Mann, Cell 2015
Category members IP bait FLNA Cat. description Hein, Mann, Cell 2015


Protein Domains in FSCN1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Actin_cross-linking IPR008999 0
Category members Fascin-domain IPR022768 0


Protein complexes (CORUM database) featuring FSCN1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring FSCN1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0003779 actin binding Database 5.41
Category members GO Category GO:0015629 actin cytoskeleton Database 2.22
Category members GO Category GO:0030036 actin cytoskeleton organization Database 1.08
Category members GO Category GO:0051015 actin filament binding Database 0.99
Category members GO Category GO:0005856 cytoskeleton Database 0.63
Category members GO Category GO:0051017 actin filament bundle assembly Database 0.47
Category members Pathway Pathway_838 SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES 0 0.35
Category members GO Category GO:0030674 protein binding, bridging Database 0.25
Category members GO Category GO:0071437 invadopodium Database 0.25
Category members GO Category GO:0008283 cell proliferation Database 0.06
Category members GO Category GO:0030175 filopodium Database 0.05
Category members GO Category GO:0001725 stress fiber Database 0.04
Category members GO Category GO:0008144 drug binding Database 0
Category members GO Category GO:0016477 cell migration Database 0
Category members GO Category GO:0030054 cell junction Database 0
Category members GO Category GO:0048870 cell motility Database 0


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