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Query: CFL2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
CFL2 0 3.594 -0.750 1.060 0.658 1.248

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
CFL2 Phosphorylation S3 0.851 -0.223 _(ac)AS(ph)GVTVNDEVIK_

Background Information for CFL2:


Pubmed-CFL2 »
Uniprot-CFL2 »
Biogrid-CFL2 »
ProteomicsDB-CFL2 »

Tumorportal-CFL2 »
COSMIC-CFL2 »
GenomeRNAi-CFL2 »
Genecards-CFL2


Protein-protein Interactions for CFL2
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CAPZA2 Cat. description Hein, Mann, Cell 2015
Category members IP bait CORO1C Cat. description Hein, Mann, Cell 2015
Category members IP bait DBN1 Cat. description Hein, Mann, Cell 2015
Category members IP bait FLNA Cat. description Hein, Mann, Cell 2015
Category members IP bait FLNB Cat. description Hein, Mann, Cell 2015
Category members IP bait IQGAP1 Cat. description Hein, Mann, Cell 2015
Category members IP bait LIMA1 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYH9 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYO18A Cat. description Hein, Mann, Cell 2015
Category members IP bait MYO19 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYO1C Cat. description Hein, Mann, Cell 2015
Category members IP bait PPP1CB Cat. description Hein, Mann, Cell 2015
Category members IP bait SYNPO Cat. description Hein, Mann, Cell 2015
Category members IP bait TMED10 Cat. description Hein, Mann, Cell 2015
Category members IP bait TPM1 Cat. description Hein, Mann, Cell 2015


Protein Domains in CFL2
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members ADF-H IPR002108 0.83
Category members ADF/Cofilin/Destrin IPR017904 0.46


Protein complexes (CORUM database) featuring CFL2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring CFL2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0003779 actin binding Database 5.41
Category members GO Category GO:0015629 actin cytoskeleton Database 2.22
Category members GO Category GO:0016363 nuclear matrix Database 1.89
Category members Pathway Pathway_838 SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES 0 0.35
Category members GO Category GO:0005622 intracellular Database 0.32
Category members Pathway Pathway_510 SIG_CHEMOTAXIS 0 0.28
Category members Pathway Pathway_961 PID_CASPASE_PATHWAY 0 0.19
Category members Pathway Pathway_499 KEGG_FC_GAMMA_R_MEDIATED_PHAGOCYTOSIS 0 0.1
Category members Pathway Pathway_580 KEGG_REGULATION_OF_ACTIN_CYTOSKELETON 0 0.08
Category members Pathway Pathway_1034 KEGG_AXON_GUIDANCE 0 0.04
Category members Disease phenotype Typical_nemaline_myopathy Typical nemaline myopathy Database 0
Category members GO Category GO:0030042 actin filament depolymerization Database 0


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