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Query: GDI1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
GDI1 1 -0.376 -1.240 2.790
GDI1 1 -0.376 -1.240 2.790 -0.675 -0.337 -0.291 0.493 -1.831

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
GDI1 Ubiquitylation K439 0.483 0.420 _MTGSEFDFEEMK(gl)R_
GDI1 Ubiquitylation K112 0.259 _VVEGSFVYK(gl)GGK_
GDI1 Ubiquitylation K115 0.259 _VVEGSFVYK(gl)GGK_
GDI1 Ubiquitylation K273 -0.488 0.081 _VIGVK(gl)SEGEIAR_
GDI1 Ubiquitylation K214 0.003 0.067 _IK(gl)LYSESLAR_
GDI1 Ubiquitylation K58 -0.561 -0.548 _NPYYGGESASITPLEDLYK(gl)R_
GDI1 Ubiquitylation K435 0.636 -0.621 _MAGTAFDFENMK(gl)R_
GDI1 Phosphorylation S65 -0.852 -0.729 _IPGS(ph)PPESMGR_

Background Information for GDI1:


Pubmed-GDI1 »
Uniprot-GDI1 »
Biogrid-GDI1 »
ProteomicsDB-GDI1 »

Tumorportal-GDI1 »
COSMIC-GDI1 »
GenomeRNAi-GDI1 »
Genecards-GDI1


Protein-protein Interactions for GDI1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait GDI1 Cat. description Hein, Mann, Cell 2015
Category members IP bait GDI1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RAB11A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RAB1A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RAB1B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RAB2B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RAB31 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RAB32 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RAB3A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RAB5A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RAB5C Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RAB6B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RAB8B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RAB9A Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in GDI1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members RabGDI IPR000806 0
Category members GDP_dissociation_inhibitor IPR018203 0


Protein complexes (CORUM database) featuring GDI1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring GDI1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0015031 protein transport Database 3.48
Category members GO Category GO:0043234 protein complex Database 2.73
Category members GO Category GO:0030496 midbody Database 0.39
Category members GO Category GO:0007264 small GTPase mediated signal transduction Database 0.37
Category members Pathway Pathway_838 SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES 0 0.35
Category members Pathway Pathway_510 SIG_CHEMOTAXIS 0 0.28
Category members GO Category GO:0051056 regulation of small GTPase mediated signal transduction Database 0.25
Category members GO Category GO:0005096 GTPase activator activity Database 0.19
Category members GO Category GO:0043005 neuron projection Database 0.08
Category members Disease phenotype X-linked_non-syndromic_intellectual_disability X-linked non-syndromic intellectual disability Database 0.01
Category members Pathway Pathway_422 PID_P38_ALPHA_BETA_DOWNSTREAM_PATHWAY 0 0
Category members Pathway Pathway_519 REACTOME_SIGNALING_BY_RHO_GTPASES 0 0
Category members GO Category GO:0005092 GDP-dissociation inhibitor activity Database 0
Category members GO Category GO:0005093 Rab GDP-dissociation inhibitor activity Database 0
Category members GO Category GO:0007165 signal transduction Database 0
Category members GO Category GO:0017137 Rab GTPase binding Database 0
Category members GO Category GO:0032482 Rab protein signal transduction Database 0
Category members GO Category GO:0050771 negative regulation of axonogenesis Database 0
Category members GO Category GO:0051592 response to calcium ion Database 0


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