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X-linked non-syndromic intellectual disability
(X-linked_non-syndromic_intellectual_disability)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
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Protein Results:

 Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
DLG3 2 0.180 -1.120 1.552 0.102 0.488
DLG3 2 0.180 -1.120
ZNF711 2 0.260 -0.490 -0.103 1.047 0.485
ZNF711 2 0.260 -0.490 -1.946 -1.054
ALG13 1 0.890 -1.050 1.053 0.029 0.494
ALG13 1 3.500 -1.400 1.053 0.029 0.494
MAGT1 1 -0.410 0.630 1.646 0.552
MAGT1 1 -0.410 0.630
RPS6KA3 1 -1.550 2.890
DMD 1 0.960 -0.560 0.854 0.214
ACSL4 0 1.120 -0.740 -0.154 -1.054 0.236 0.117
MID2 0 0.370 -0.940 -0.219 0.525
USP9X 0 -0.520 0.800 -0.309 0.196 0.205 -0.019 0.128
UPF3B 0 -0.820 0.890 -0.652 -0.447
ARHGEF6 0 0.570 -0.210
ARHGEF6 0 0.570 -0.210
MED12 0 -0.180 -0.500 -1.501 -0.491

PTM Sites:

 Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
ACSL4 Ubiquitylation K49 -1.745 _AK(gl)PTSDKPGSPYR_
ACSL4 Ubiquitylation K54 -1.457 _AKPTSDK(gl)PGSPYR_
ACSL4 Ubiquitylation K354 0.109 0.988 _IGYSSPLTLSDQSSK(gl)IK_
ACSL4 Ubiquitylation K356 0.153 0.800 _IGYSSPLTLSDQSSKIK(gl)_
ACSL4 Ubiquitylation K500 -1.017 -0.639 _LK(gl)DWQEGGYTINDKPNPR_
ACSL4 Ubiquitylation K621 0.455 0.184 _SDQSYVISFVVPNQK(gl)R_
ACSL4 Ubiquitylation K661 0.291 0.519 _EAANAM(ox)K(gl)LER_
ACSL4 Ubiquitylation K670 -0.058 -0.343 _FEIPIK(gl)VR_
ACSL4 Ubiquitylation K702 0.575 _NHYLK(gl)DIER_
ALG13 Ubiquitylation K68 0.277 _YKDSLK(gl)EDIQK_
ALG13 Ubiquitylation K94 -0.565 _GK(gl)PLVVVINEK_
ALG13 Ubiquitylation K137 -0.814 _VLTCPGQAK(gl)SIASAPGK_
ALG13 Phosphorylation S216 1.020 _S(ph)LNEASMDEYLGSLGLFR_
ALG13 Ubiquitylation K238 -0.752 _KLTAK(gl)DASCLFR_
ALG13 Ubiquitylation K263 0.896 _K(gl)ACVSYMR_
ALG13 Ubiquitylation K386 -0.264 _TAIK(gl)LFR_
ALG13 Ubiquitylation K411 -0.507 _NNAVTGSEDAHTDYK(gl)SSNQNR_
ALG13 Ubiquitylation K458 -0.539 _VLK(gl)ALDPEIYR_
ALG13 Ubiquitylation K482 0.513 _ELQK(gl)SDYMEYAGR_
ALG13 Ubiquitylation K683 -0.785 _VDFYPGPGK(gl)R_
ARHGEF6 Phosphorylation S225 -0.163 -0.076 _SSERPLS(ph)PK_
ARHGEF6 Phosphorylation S415 0.662 0.947 _M(ox)S(ph)GFIYQGK_
ARHGEF6 Phosphorylation S600 0.797 _S(ph)TAALEEDAQILK_
ARHGEF6 Phosphorylation T601 0.797 _S(ph)TAALEEDAQILK_
ARHGEF6 Phosphorylation S684 0.068 -0.061 _KDS(ph)IPQVLLPEEEKLIIEETR_
DLG3 Phosphorylation S102 -1.455 _SKPSEPIQPVNTWEISSLPSSTVTSETLPSSLS(ph)PSVEK_
DLG3 Phosphorylation T115 -0.707 -1.378 _YQDEDT(ph)PPQEHISPQITNEVIGPELVHVSEK_
DLG3 Phosphorylation S122 -1.073 _YQDEDTPPQEHIS(ph)PQITNEVIGPELVHVSEK_
DLG3 Phosphorylation S158 0.773 _NLSEIENVHGFVSHSHIS(ph)PIK_
DLG3 Ubiquitylation K321 1.264 1.435 _IMEIK(gl)LIK_
DLG3 Ubiquitylation K361 0.180 _IIEGGAAHK(gl)DGK_
DLG3 Ubiquitylation K368 1.043 1.755 _IIEGGAAQK(gl)DGR_
DLG3 Ubiquitylation K452 -0.704 _YSPVSK(gl)AVLGDDEITREPR_
DLG3 Ubiquitylation K556 0.105 _FEAK(gl)IHDLR_
DLG3 Phosphorylation S573 0.697 _EQM(ox)M(ox)NSSISSGS(ph)GSLR_
DLG3 Phosphorylation S575 0.255 0.729 _EQMMNSSISSGSGS(ph)LR_
DLG3 Ubiquitylation K843 1.259 _SMENIMEMNK(gl)R_
DMD Ubiquitylation K3317 -0.200 -0.978 _CNICK(gl)ECPIIGFR_
DMD Phosphorylation S3623 2.940 0.225 _SDS(ph)SQPMLLR_
MAGT1 Ubiquitylation K72 -0.120 _MNGDK(gl)FR_
MAGT1 Ubiquitylation K82 0.038 _VSQLM(ox)EWTNK(gl)RPVIR_
MED12 Ubiquitylation K429 -0.439 _EIEQQIK(gl)ER_
MED12 Ubiquitylation K531 -0.272 _AMVVAKLLEK(gl)_
MED12 Phosphorylation S635 -1.278 -0.801 _GDLAFGAPGPRPPS(ph)PFDDPADDPEHK_
MED12 Ubiquitylation K1001 -1.092 _VK(gl)NTIYCNVEPSESNMR_
MED12 Ubiquitylation K1661 -1.781 _DVITCEPQGSLIDTK(gl)GNK_
MED12 Ubiquitylation K1682 -0.745 _EGLQVSTK(gl)QK_
MED12 Ubiquitylation K1684 -0.960 _EGLQVSTK(gl)QK_
MID2 Ubiquitylation K74 0.275 0.651 _GLDGLK(gl)R_
MID2 Phosphorylation S96 -0.141 0.050 _ASVSGPNS(ph)PSETRR_
RPS6KA3 Phosphorylation S227 0.363 0.496 _AYS(ph)FCGTVEYM(ox)APEVVNR_
RPS6KA3 Phosphorylation T231 0.315 _KAYSFCGT(ph)VEYMAPEVVNR_
RPS6KA3 Ubiquitylation K322 -0.076 -0.376 _LGAGPDGVEEIK(gl)R_
RPS6KA3 Phosphorylation T365 -0.892 -1.003 _T(ph)PKDSPGIPPSANAHQLFR_
RPS6KA3 Phosphorylation S369 -0.621 -0.862 _TPKDS(ph)PGIPPSANAHQLFR_
RPS6KA3 Ubiquitylation K566 -0.152 _ICDFGFAK(gl)QLR_
RPS6KA3 Phosphorylation S715 -0.923 -0.880 _NQS(ph)PVLEPVGR_
UPF3B Ubiquitylation K196 0.208 _K(gl)TTPLLSFLK_
USP9X Ubiquitylation K112 0.155 0.666 _GLDVK(gl)SEACQR_
USP9X Ubiquitylation K315 1.100 _SLK(gl)NLASR_
USP9X Ubiquitylation K1045 0.212 _VLMK(gl)LMPPDSTTIEK_
USP9X Ubiquitylation K1445 -1.104 -0.276 _ELLAFQTSEK(gl)K_
USP9X Ubiquitylation K1446 -1.104 0.061 _ELLAFQTSEKK(gl)_
USP9X Ubiquitylation K1627 -1.695 _DDVFGYPQQFEDK(gl)PALSK_
USP9X Ubiquitylation K1637 -0.957 _TEDRK(gl)EYNIGVLR_
USP9X Ubiquitylation K1798 -1.085 _LPPVLAIQLK(gl)R_
USP9X Ubiquitylation K2301 0.210 0.500 _IIEDCSNSEETVK(gl)LLR_
USP9X Ubiquitylation K2480 -0.335 _ACELCPEEVKK(gl)_
USP9X Phosphorylation S2563 -0.389 -0.274 _AQENYEGSEEVS(ph)PPQTK_
ZNF711 Phosphorylation S3 -0.322 1.462 _(ac)MDS(ph)GGGSLGLHTPDSR_
ZNF711 Phosphorylation S7 -0.322 0.864 _(ac)MDSGGGS(ph)LGLHTPDSR_
ZNF711 Phosphorylation T12 3.265 1.178 _(ac)MDSGGGSLGLHT(ph)PDSR_
ZNF711 Phosphorylation S198 -0.122 _TEDDDDDDVKS(ph)TSEDYLMISLDDVGEKLEHMGNTPLK_
ZNF711 Phosphorylation S230 2.744 2.431 _IGSDGS(ph)QEDAKEDGFGSEVIK_
ZNF711 Ubiquitylation K235 -1.779 -0.975 _IGSDGSQEDAK(gl)EDGFGSEVIK_
ZNF711 Ubiquitylation K289 -0.680 0.291 _EK(gl)MVYMAVK_
ZNF711 Phosphorylation S298 1.554 _DS(ph)SQEEDDIRDER_
ZNF711 Phosphorylation S299 1.721 1.678 _DSS(ph)QEEDDIRDER_
ZNF711 Phosphorylation S313 -0.303 -0.112 _ADPGEDDLGGTVDIVES(ph)EPENDHGVELLDQNSSIR_
ZNF711 Phosphorylation T324 0.712 _RYEDCQASGNT(ph)LDSALESR_
ZNF711 Ubiquitylation K350 -0.907 _SSTAAQYLQICDGINTNK(gl)VLK_
ZNF711 Ubiquitylation K426 -0.343 _YQCTDCDFTTNKK(gl)_
ZNF711 Ubiquitylation K444 -0.190 _VDK(gl)THEFTEYTR_
ZNF711 Phosphorylation S459 -0.089 -0.149 _YREAS(ph)PLSSNK_
ZNF711 Phosphorylation S462 -0.485 -0.273 _YREASPLS(ph)SNK_
ZNF711 Ubiquitylation K465 -1.088 _EASPLSSNK(gl)LILR_
ZNF711 Ubiquitylation K549 0.128 _CADQSNLK(gl)THIK_
ZNF711 Ubiquitylation K720 0.345 _IYQCEYCEYSTTDASGFK(gl)R_


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