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Query: USP9X

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
USP9X 0 1.648 -0.520 0.800 -0.309 0.196 0.205 -0.019 0.128

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
USP9X Ubiquitylation K315 1.100 _SLK(gl)NLASR_
USP9X Ubiquitylation K112 0.155 0.666 _GLDVK(gl)SEACQR_
USP9X Ubiquitylation K2301 0.210 0.500 _IIEDCSNSEETVK(gl)LLR_
USP9X Ubiquitylation K1045 0.212 _VLMK(gl)LMPPDSTTIEK_
USP9X Ubiquitylation K1446 -1.104 0.061 _ELLAFQTSEKK(gl)_
USP9X Phosphorylation S2563 -0.389 -0.274 _AQENYEGSEEVS(ph)PPQTK_
USP9X Ubiquitylation K1445 -1.104 -0.276 _ELLAFQTSEK(gl)K_
USP9X Ubiquitylation K1798 -1.085 _LPPVLAIQLK(gl)R_
USP9X Ubiquitylation K1627 -1.695 _DDVFGYPQQFEDK(gl)PALSK_
USP9X Ubiquitylation K1637 -0.957 _TEDRK(gl)EYNIGVLR_
USP9X Ubiquitylation K2480 -0.335 _ACELCPEEVKK(gl)_

Background Information for USP9X:


Pubmed-USP9X »
Uniprot-USP9X »
Biogrid-USP9X »
ProteomicsDB-USP9X »

Tumorportal-USP9X »
COSMIC-USP9X »
GenomeRNAi-USP9X »
Genecards-USP9X


Protein-protein Interactions for USP9X
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ATP7A Cat. description Hein, Mann, Cell 2015
Category members IP bait ECM29;KIAA0368 Cat. description Hein, Mann, Cell 2015
Category members IP bait MSN Cat. description Hein, Mann, Cell 2015
Category members IP bait NEDD1 Cat. description Hein, Mann, Cell 2015
Category members IP bait OXNAD1 Cat. description Hein, Mann, Cell 2015
Category members IP bait SOD1 Cat. description Hein, Mann, Cell 2015
Category members IP bait HEXIM2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PEG10 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SUPV3L1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SUV39H1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNF263 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNF408 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in USP9X
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members ARM-type_fold IPR016024 9.26
Category members Ubiquitin-rel_dom IPR029071 1.79
Category members UCH/PAN2 IPR028889 0.62
Category members Peptidase_C19_UCH IPR001394 0.53


Protein complexes (CORUM database) featuring USP9X
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 783 ITCH-FAM/USP9x complex Database 0


Categories featuring USP9X
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0010467 gene expression Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0005488 binding Database 9.32
Category members GO Category GO:0006511 ubiquitin-dependent protein catabolic process Database 3.57
Category members GO Category GO:0007067 mitosis Database 2.23
Category members GO Category GO:0004221 ubiquitin thiolesterase activity Database 1.36
Category members GO Category GO:0016579 protein deubiquitination Database 1.32
Category members GO Category GO:0006351 transcription, DNA-templated Database 1.07
Category members Pathway Pathway_777 REACTOME_SIGNALING_BY_TGF_BETA_RECEPTOR_COMPLEX 0 0.89
Category members GO Category GO:0004197 cysteine-type endopeptidase activity Database 0.38
Category members GO Category GO:0006367 transcription initiation from RNA polymerase II promoter Database 0.25
Category members GO Category GO:0007179 transforming growth factor beta receptor signaling pathway Database 0.25
Category members GO Category GO:0030509 BMP signaling pathway Database 0.2
Category members Pathway Pathway_802 REACTOME_TRANSCRIPTIONAL_ACTIVITY_OF_SMAD2_SMAD3_SMAD4_HETEROTRIMER 0 0.17
Category members GO Category GO:0007292 female gamete generation Database 0.16
Category members GO Category GO:0007059 chromosome segregation Database 0.13
Category members Pathway Pathway_822 REACTOME_GENERIC_TRANSCRIPTION_PATHWAY 0 0.09
Category members Pathway Pathway_823 REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY 0 0.07
Category members GO Category GO:0070410 co-SMAD binding Database 0.03
Category members GO Category GO:0000122 negative regulation of transcription from RNA polymerase II promoter Database 0.02
Category members Disease phenotype X-linked_non-syndromic_intellectual_disability X-linked non-syndromic intellectual disability Database 0.01
Category members GO Category GO:0008234 cysteine-type peptidase activity Database 0
Category members GO Category GO:0045177 apical part of cell Database 0


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