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Query: ALG13

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
ALG13 1 3.492 0.890 -1.050 1.053 0.029 0.494
ALG13 1 3.492 3.500 -1.400 1.053 0.029 0.494

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
ALG13 Phosphorylation S216 1.020 _S(ph)LNEASMDEYLGSLGLFR_
ALG13 Ubiquitylation K263 0.896 _K(gl)ACVSYMR_
ALG13 Ubiquitylation K482 0.513 _ELQK(gl)SDYMEYAGR_
ALG13 Ubiquitylation K68 0.277 _YKDSLK(gl)EDIQK_
ALG13 Ubiquitylation K386 -0.264 _TAIK(gl)LFR_
ALG13 Ubiquitylation K411 -0.507 _NNAVTGSEDAHTDYK(gl)SSNQNR_
ALG13 Ubiquitylation K458 -0.539 _VLK(gl)ALDPEIYR_
ALG13 Ubiquitylation K94 -0.565 _GK(gl)PLVVVINEK_
ALG13 Ubiquitylation K238 -0.752 _KLTAK(gl)DASCLFR_
ALG13 Ubiquitylation K683 -0.785 _VDFYPGPGK(gl)R_
ALG13 Ubiquitylation K137 -0.814 _VLTCPGQAK(gl)SIASAPGK_

Background Information for ALG13:





Protein-protein Interactions for ALG13

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CDC16 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait EGFL6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ELAVL2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PLOD1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PLSCR4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PRG2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait WDFY3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in ALG13

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Tudor IPR002999 0.28
Category members OTU IPR003323 0.18
Category members Glyco_trans_28_C IPR007235 0


Protein complexes (CORUM database) featuring ALG13

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring ALG13

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Pathway Pathway_11 REACTOME_METABOLISM_OF_PROTEINS 0 12.01
Category members GO Category GO:0044267 cellular protein metabolic process Database 10.42
Category members GO Category GO:0005789 endoplasmic reticulum membrane Database 1.57
Category members GO Category GO:0006488 dolichol-linked oligosaccharide biosynthetic process Database 0.28
Category members Pathway Pathway_93 REACTOME_BIOSYNTHESIS_OF_THE_N_GLYCAN_PRECURSOR_DOLICHOL_LIPID_LINKED_OLIGOSACCHARIDE_LLO_AND_TRANSFER_TO_A_NASCENT_PROTEIN 0 0.18
Category members GO Category GO:0005975 carbohydrate metabolic process Database 0.07
Category members Pathway Pathway_109 KEGG_N_GLYCAN_BIOSYNTHESIS 0 0.04
Category members Disease phenotype X-linked_non-syndromic_intellectual_disability X-linked non-syndromic intellectual disability Database 0.01
Category members Pathway Pathway_94 REACTOME_POST_TRANSLATIONAL_PROTEIN_MODIFICATION 0 0
Category members Pathway Pathway_95 REACTOME_ASPARAGINE_N_LINKED_GLYCOSYLATION 0 0
Category members Disease phenotype epileptic_encephalopathies epileptic encephalopathies Database 0
Category members GO Category GO:0006508 proteolysis Database 0
Category members GO Category GO:0008234 cysteine-type peptidase activity Database 0
Category members GO Category GO:0016758 transferase activity, transferring hexosyl groups Database 0
Category members GO Category GO:0018279 protein N-linked glycosylation via asparagine Database 0
Category members GO Category GO:0030246 carbohydrate binding Database 0
Category members GO Category GO:0030259 lipid glycosylation Database 0
Category members GO Category GO:0043687 post-translational protein modification Database 0


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