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Query: VASP

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
VASP 1 1.970 0.180 0.270 1.849

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
VASP Phosphorylation S239 0.625 -0.774 _VS(ph)KQEEASGGPTAPK_

Background Information for VASP:


Pubmed-VASP »
Uniprot-VASP »
Biogrid-VASP »
ProteomicsDB-VASP »

Tumorportal-VASP »
COSMIC-VASP »
GenomeRNAi-VASP »
Genecards-VASP


Protein-protein Interactions for VASP
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait TACC3 Cat. description Hein, Mann, Cell 2015
Category members IP bait PFN2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RAB30 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TEAD4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TTC23L Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait VASP Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in VASP
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members VASP_tetra IPR014885 0.29
Category members Vasodilator_phosphoprotein IPR017354 0.09
Category members WH1/EVH1 IPR000697 0


Protein complexes (CORUM database) featuring VASP
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 3160 RIAM-VASP complex Database 0.17


Categories featuring VASP
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0003779 actin binding Database 5.41
Category members Pathway Pathway_621 REACTOME_ADAPTIVE_IMMUNE_SYSTEM 0 4.72
Category members Pathway Pathway_458 REACTOME_IMMUNE_SYSTEM 0 3
Category members GO Category GO:0015629 actin cytoskeleton Database 2.22
Category members GO Category GO:0030027 lamellipodium Database 1.77
Category members Pathway Pathway_466 PID_ECADHERIN_STABILIZATION_PATHWAY 0 1.4
Category members Pathway Pathway_309 ST_INTEGRIN_SIGNALING_PATHWAY 0 1.35
Category members Pathway Pathway_611 PID_ECADHERIN_KERATINOCYTE_PATHWAY 0 1.34
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members Pathway Pathway_595 KEGG_FOCAL_ADHESION 0 1.08
Category members GO Category GO:0030036 actin cytoskeleton organization Database 1.08
Category members Pathway Pathway_673 REACTOME_AXON_GUIDANCE 0 1.06
Category members GO Category GO:0031527 filopodium membrane Database 0.74
Category members GO Category GO:0005923 tight junction Database 0.69
Category members GO Category GO:0005925 focal adhesion Database 0.68
Category members GO Category GO:0005856 cytoskeleton Database 0.63
Category members Pathway Pathway_662 PID_IL8_CXCR2_PATHWAY 0 0.62
Category members GO Category GO:0008154 actin polymerization or depolymerization Database 0.47
Category members GO Category GO:0051289 protein homotetramerization Database 0.44
Category members GO Category GO:0005522 profilin binding Database 0.44
Category members Pathway Pathway_838 SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES 0 0.35
Category members Pathway Pathway_42 REACTOME_DEVELOPMENTAL_BIOLOGY 0 0.32
Category members GO Category GO:0034329 cell junction assembly Database 0.29
Category members Pathway Pathway_560 REACTOME_CELL_CELL_COMMUNICATION 0 0.25
Category members Pathway Pathway_701 REACTOME_GENERATION_OF_SECOND_MESSENGER_MOLECULES 0 0.22
Category members Pathway Pathway_605 KEGG_LEUKOCYTE_TRANSENDOTHELIAL_MIGRATION 0 0.2
Category members Pathway Pathway_573 REACTOME_TCR_SIGNALING 0 0.2
Category members Pathway Pathway_428 PID_THROMBIN_PAR1_PATHWAY 0 0.18
Category members Pathway Pathway_923 REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS 0 0.18
Category members GO Category GO:0031258 lamellipodium membrane Database 0.15
Category members GO Category GO:0007411 axon guidance Database 0.13
Category members Pathway Pathway_499 KEGG_FC_GAMMA_R_MEDIATED_PHAGOCYTOSIS 0 0.1
Category members GO Category GO:0050852 T cell receptor signaling pathway Database 0.06
Category members GO Category GO:0030175 filopodium Database 0.05
Category members Pathway Pathway_1031 REACTOME_SIGNALING_BY_ROBO_RECEPTOR 0 0
Category members Pathway Pathway_925 REACTOME_CELL_JUNCTION_ORGANIZATION 0 0
Category members GO Category GO:0001843 neural tube closure Database 0
Category members GO Category GO:0017124 SH3 domain binding Database 0


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