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Query: DIABLO

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
DIABLO 0 0.956 0.740 -0.290 0.517 0.500
DIABLO 0 0.956 0.740 -0.290 -0.061

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence

Background Information for DIABLO:


Pubmed-DIABLO »
Uniprot-DIABLO »
Biogrid-DIABLO »
ProteomicsDB-DIABLO »

Tumorportal-DIABLO »
COSMIC-DIABLO »
GenomeRNAi-DIABLO »
Genecards-DIABLO


Protein-protein Interactions for DIABLO
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait LIMA1 Cat. description Hein, Mann, Cell 2015
Category members IP bait BIRC7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait BIRC8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DIABLO Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait KLHL2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in DIABLO
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Smac_DIABLO-like IPR009062 0


Protein complexes (CORUM database) featuring DIABLO
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring DIABLO
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members Pathway Pathway_837 REACTOME_APOPTOSIS 0 2.39
Category members GO Category GO:0006915 apoptotic process Database 2.12
Category members GO Category GO:0005739 mitochondrion Database 1.67
Category members GO Category GO:0005758 mitochondrial intermembrane space Database 0.33
Category members GO Category GO:0043065 positive regulation of apoptotic process Database 0.26
Category members GO Category GO:0051402 neuron apoptotic process Database 0.25
Category members Pathway Pathway_961 PID_CASPASE_PATHWAY 0 0.19
Category members GO Category GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process Database 0.08
Category members Pathway Pathway_557 PID_P75_NTR_PATHWAY 0 0.04
Category members Pathway Pathway_386 ST_FAS_SIGNALING_PATHWAY 0 0.02
Category members Pathway Pathway_1012 BIOCARTA_MITOCHONDRIA_PATHWAY 0 0
Category members Pathway Pathway_990 REACTOME_INTRINSIC_PATHWAY_FOR_APOPTOSIS 0 0
Category members Disease phenotype Autosomal_dominant_nonsyndromic_sensorineural_deafness_type_DFNA Autosomal dominant nonsyndromic sensorineural deafness type DFNA Database 0
Category members GO Category GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors Database 0
Category members GO Category GO:0008631 intrinsic apoptotic signaling pathway in response to oxidative stress Database 0
Category members GO Category GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c Database 0
Category members GO Category GO:0009898 cytoplasmic side of plasma membrane Database 0
Category members GO Category GO:0035631 CD40 receptor complex Database 0


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