bioLOGIC Data » bioLOGIC CategoryView » bioLOGIC VennView » Experimental Details »

bioLOGIC Category

Results for the Category
extrinsic apoptotic signaling pathway via death domain receptors
(GO:0008625)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
W

Protein Results:

 Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
DDX3X 2 -0.250 0.370 0.081 -0.794 -0.166 -0.062 -0.025
CASP8 1 1.120 -1.090
BAG3 1 0.180 -0.820
BAD 0 -0.660 1.190
FAS 0 1.380 -1.070
FAS 0 1.380 -1.070
TNFRSF1A 0 -0.590 0.470
BAX 0 1.590 -1.170 0.811 0.359
TNFRSF10B 0 -0.030 -0.780
SORT1 0
ROCK2 0 -1.660 2.330
PIK3R1 0 1.910 -1.220 -0.441 0.147
DEDD 0 0.120 -0.510
DEDD2 0 0.690 -0.270
CASP3 0 0.570 -0.390
GABARAP 0 -1.090 2.300
BCL2 0 0.910 -0.740
DIABLO 0 0.740 -0.290 0.517 0.500
DIABLO 0 0.740 -0.290 -0.061
NF1 0 1.000 -0.500 0.444 -0.190
DAPK1 0 -0.090 -0.480 -1.111
DDX47 0 -0.690 0.360 -1.395 -0.368 -0.261 -0.050

PTM Sites:

 Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
BAD Phosphorylation S74 -0.904 -0.452 _HS(ph)SYPAGTEDDEGM(ox)GEEPSPFR_
BAD Phosphorylation S75 -0.914 -0.660 _HSS(ph)YPAGTEDDEGMGEEPSPFR_
BAD Phosphorylation S97 0.056 _S(ph)RSAPPNLWAAQR_
BAD Phosphorylation S99 -0.299 0.161 _S(ph)APPNLWAAQR_
BAD Phosphorylation S118 1.277 1.089 _RM(ox)S(ph)DEFVDSFKK_
BAG3 Phosphorylation S173 -0.549 -0.580 _SQS(ph)PAASDCSSSSSSASLPSSGR_
BAG3 Phosphorylation S194 -0.402 -0.523 _S(ph)SLGSHQLPR_
BAG3 Phosphorylation S195 0.244 -0.933 _SS(ph)LGSHQLPR_
BAG3 Phosphorylation S289 4.691 -1.292 _SSTPLHS(ph)PSPIR_
BAG3 Phosphorylation S291 0.973 -1.061 _SSTPLHSPS(ph)PIR_
BAG3 Phosphorylation S377 -2.611 -2.836 _VPPAPVPCPPPS(ph)PGPSAVPSSPK_
BAG3 Phosphorylation S381 -1.826 _VPPAPVPCPPPSPGPS(ph)AVPS(ph)SPK_
BAG3 Phosphorylation S385 -3.389 -1.522 _VPPAPVPCPPPS(ph)PGPSAVPS(ph)SPK_
BAG3 Phosphorylation S386 -3.389 -3.269 _VPPAPVPCPPPS(ph)PGPSAVPSS(ph)PK_
BAX Ubiquitylation K57 -1.174 _MGGEAPELALDPVPQDASTK(gl)K_
BAX Ubiquitylation K58 -1.718 -1.174 _MGGEAPELALDPVPQDASTKK(gl)_
BAX Ubiquitylation K64 0.708 1.306 _LSECLK(gl)R_
BCL2 Ubiquitylation K22 1.480 _YIHYK(gl)LSQR_
CASP3 Ubiquitylation K11 -0.053 -0.687 _(ac)MENTENSVDSK(gl)SIK_
CASP3 Ubiquitylation K14 -0.455 -0.687 _SIK(gl)NLEPK_
CASP3 Ubiquitylation K57 -0.304 -1.817 _NFHK(gl)STGMTSR_
CASP3 Ubiquitylation K82 -0.268 -0.605 _NLK(gl)YEVR_
CASP8 Ubiquitylation K183 1.917 _IINDYEEFSK(gl)ER_
CASP8 Ubiquitylation K461 -2.031 _NMGK(gl)QMPQPTFTLR_
DAPK1 Ubiquitylation K939 0.937 0.001 _LFVLDAGASGSK(gl)DMK_
DDX3X Ubiquitylation K78 1.311 _DK(gl)DAYSSFGSR_
DDX3X Ubiquitylation K93 0.657 1.846 _GK(gl)SSFFSDR_
DDX3X Phosphorylation S94 0.172 _S(ph)SFFSDRGSGSR_
DDX3X Phosphorylation S102 0.008 0.230 _SSFFSDRGS(ph)GSR_
DDX3X Phosphorylation S104 -0.231 0.320 _SSFFSDRGSGS(ph)R_
DDX3X Ubiquitylation K130 1.572 1.502 _SGFGK(gl)FER_
DDX3X Ubiquitylation K347 -0.406 0.360 _GK(gl)IGLDFCK_
DDX3X Ubiquitylation K503 -0.796 _SGK(gl)SPILVATAVAAR_
DDX3X Phosphorylation S602 -0.349 _S(ph)SRFSGGFGAR_
DDX3X Phosphorylation S603 -0.330 _SS(ph)RFSGGFGAR_
DDX3X Phosphorylation S606 -0.248 -0.447 _FS(ph)GGFGAR_
DDX47 Phosphorylation S9 -0.708 -0.879 _(ac)AAPEEHDS(ph)PT(ph)EASQPIVEEEETK_
DDX47 Phosphorylation T11 1.396 -0.790 _(ac)AAPEEHDS(ph)PT(ph)EASQPIVEEEETK_
DDX47 Phosphorylation S14 1.136 0.816 _(ac)AAPEEHDSPTEAS(ph)QPIVEEEETK_
DEDD Ubiquitylation K237 0.372 _FNQANTILK(gl)SR_
DEDD2 Ubiquitylation K193 -2.121 _GAPAAPQQQSEPARPSSEGK(gl)VTCDIR_
FAS Phosphorylation S236 -0.027 _ENQGS(ph)HESPTLNPETVAINLSDVDLSK_
FAS Phosphorylation S239 0.266 _ENQGSHES(ph)PTLNPETVAINLSDVDLSK_
FAS Ubiquitylation K343 1.126 _IQTIILK(gl)DITSDSENSNFR_
GABARAP Ubiquitylation K13 -0.569 _FVYKEEHPFEK(gl)R_
NF1 Ubiquitylation K471 0.218 _MAPSLTFKEK(gl)_
NF1 Phosphorylation S864 -0.458 _SNSGLATYS(ph)PPMGPVSER_
NF1 Phosphorylation T2514 0.076 _GSEGYLAATYPTVGQT(ph)SPR_
NF1 Phosphorylation S2515 0.071 0.316 _GSEGYLAATYPTVGQTS(ph)PR_
NF1 Phosphorylation S2543 0.698 0.655 _S(ph)FDHLISDTK_
ROCK2 Ubiquitylation K1222 -0.679 _ADAK(gl)EIPR_
SORT1 Ubiquitylation K294 -0.104 _TSDLGK(gl)SFK_
SORT1 Ubiquitylation K388 -2.073 -0.343 _GIVYSK(gl)SLDR_
TNFRSF10B Ubiquitylation K369 -0.724 _KLGLMDNEIK(gl)VAK_
TNFRSF1A Ubiquitylation K242 -0.111 _SK(gl)LYSIVCGK_


.

© Copyright Svejstrup Laboratory 2015