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Query: TNFRSF10B

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
TNFRSF10B 0 -0.724 -0.030 -0.780

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
TNFRSF10B Ubiquitylation K369 -0.724 _KLGLMDNEIK(gl)VAK_

Background Information for TNFRSF10B:


Pubmed-TNFRSF10B »
Uniprot-TNFRSF10B »
Biogrid-TNFRSF10B »
ProteomicsDB-TNFRSF10B »

Tumorportal-TNFRSF10B »
COSMIC-TNFRSF10B »
GenomeRNAi-TNFRSF10B »
Genecards-TNFRSF10B


Protein-protein Interactions for TNFRSF10B
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait BMPR1A Cat. description Hein, Mann, Cell 2015
Category members IP bait ACCN2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ARRDC3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C6orf72 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FYN Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HEPACAM2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait IL1R1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LRRIQ1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LTBR Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MICA Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RNF11 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SLC1A1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TMEM223 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TMEM231 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TNFRSF10A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TNFRSF10B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TNFRSF13B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TSPAN3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in TNFRSF10B
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members DEATH-like_dom IPR011029 1.15
Category members Death_domain IPR000488 0.08
Category members TNFR_10 IPR020465 0.04
Category members TNFR/NGFR_Cys_rich_reg IPR001368 0


Protein complexes (CORUM database) featuring TNFRSF10B
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring TNFRSF10B
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members Pathway Pathway_837 REACTOME_APOPTOSIS 0 2.39
Category members GO Category GO:0006915 apoptotic process Database 2.12
Category members Pathway Pathway_448 KEGG_CYTOKINE_CYTOKINE_RECEPTOR_INTERACTION 0 2.05
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0070059 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress Database 0.91
Category members GO Category GO:0042981 regulation of apoptotic process Database 0.79
Category members Pathway Pathway_382 KEGG_P53_SIGNALING_PATHWAY 0 0.26
Category members Pathway Pathway_383 PID_P53_DOWNSTREAM_PATHWAY 0 0.23
Category members Pathway Pathway_596 PID_TRAIL_PATHWAY 0 0.17
Category members GO Category GO:0007250 activation of NF-kappaB-inducing kinase activity Database 0.17
Category members Pathway Pathway_1082 REACTOME_EXTRINSIC_PATHWAY_FOR_APOPTOSIS 0 0.16
Category members GO Category GO:0007166 cell surface receptor signaling pathway Database 0.1
Category members GO Category GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process Database 0.08
Category members GO Category GO:0034976 response to endoplasmic reticulum stress Database 0.06
Category members GO Category GO:0045569 TRAIL binding Database 0.04
Category members Pathway Pathway_1020 BIOCARTA_DEATH_PATHWAY 0 0
Category members Pathway Pathway_572 KEGG_APOPTOSIS 0 0
Category members Pathway Pathway_646 KEGG_NATURAL_KILLER_CELL_MEDIATED_CYTOTOXICITY 0 0
Category members Disease phenotype SQUAMOUS_CELL_CARCINOMA_HEAD_AND_NECK SQUAMOUS CELL CARCINOMA HEAD AND NECK Database 0
Category members Disease phenotype Squamous_cell_carcinoma_of_head_and_neck Squamous cell carcinoma of head and neck Database 0
Category members GO Category GO:0004872 receptor activity Database 0
Category members GO Category GO:0007165 signal transduction Database 0
Category members GO Category GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors Database 0
Category members GO Category GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling Database 0
Category members GO Category GO:0071260 cellular response to mechanical stimulus Database 0


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