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Results for the Category
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
(GO:0070059)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
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Protein Results:

 Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
ITPR1 2 -0.040 0.000 1.489 1.835
ITPR1 2 -0.040 0.000 0.768 0.643
ATP2A1 2 -1.020 1.690 0.192 -0.474 0.081 0.297
BAK1 1 0.710 0.160 -0.419 2.039
DNAJC10 1 -1.750 3.210 0.769 -0.495 -0.158 0.513 0.706
PML 1 -0.420 0.350 -0.244 0.322
AIFM1 1 1.570 0.130 0.210 0.652 -1.014 0.280 0.386
UBE2K 0 -0.480 0.600
BAX 0 1.590 -1.170 0.811 0.359
TNFRSF10B 0 -0.030 -0.780
ATF4 0 -1.090 1.510
CHAC1 0 -0.520 0.590
TMBIM6 0 0.680 -0.550
BCL2 0 0.910 -0.740
EIF2AK3 0 0.010 0.340
BRSK2 0 1.070 -0.640
ERO1L 0 -0.250 -0.050 1.365 -0.072

PTM Sites:

 Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
AIFM1 Ubiquitylation K111 1.676 _ISGLGLTPEQKQK(gl)_
AIFM1 Ubiquitylation K518 -0.545 -0.262 _ATAQDNPK(gl)SATEQSGTGIR_
ATF4 Phosphorylation S69 0.252 _AGSSEWLAVDGLVS(ph)PSNNSK_
ATF4 Phosphorylation S248 0.569 -0.323 _SLPS(ph)PGVLCGSAR_
ATF4 Ubiquitylation K267 -1.961 _PYDPPGEK(gl)MVAAK_
ATF4 Ubiquitylation K329 -0.035 _ADSLAK(gl)EIQYLK_
ATP2A1 Ubiquitylation K169 2.444 3.235 _LTSIK(gl)STTLR_
ATP2A1 Ubiquitylation K436 2.681 _GVYEK(gl)VGEATETALTCLVEK_
ATP2A1 Ubiquitylation K460 0.597 2.302 _MNVFDTELK(gl)GLSK_
ATP2A1 Ubiquitylation K464 1.160 3.034 _GLSK(gl)IER_
ATP2A1 Ubiquitylation K476 1.817 3.302 _ANACNSVIK(gl)QLMK_
ATP2A1 Ubiquitylation K480 2.106 _ANACNSVIKQLMK(gl)_
ATP2A1 Ubiquitylation K492 0.229 _K(gl)SMSVYCTPNKPSR_
ATP2A1 Ubiquitylation K502 -0.998 1.220 _SMSVYCTPNK(gl)PSR_
ATP2A1 Ubiquitylation K510 1.498 2.485 _TSMSK(gl)MFVK_
ATP2A1 Ubiquitylation K514 1.598 2.466 _MFVK(gl)GAPEGVIDR_
ATP2A1 Ubiquitylation K533 1.659 2.743 _VGSTK(gl)VPMTSGVK_
ATP2A1 Ubiquitylation K541 2.787 _VPMTSGVK(gl)QK_
ATP2A1 Ubiquitylation K543 1.447 3.874 _QK(gl)IMSVIR_
ATP2A1 Ubiquitylation K611 5.174 4.269 _IEVASSVK(gl)LCR_
ATP2A1 Ubiquitylation K628 0.545 2.714 _VIMITGDNK(gl)GTAVAICR_
ATP2A1 Ubiquitylation K650 1.861 2.614 _IGIFGQDEDVTSK(gl)AFTGR_
ATP2A1 Phosphorylation S663 0.605 0.621 _EFDELNPS(ph)AQR_
ATP2A1 Ubiquitylation K712 2.111 _K(gl)AEIGIAMGSGTAVAK_
ATP2A1 Ubiquitylation K757 2.081 3.431 _AIYNNMK(gl)QFIR_
ATP2A1 Ubiquitylation K995 -1.164 1.549 _NYLEPGK(gl)ECVQPATK_
BAX Ubiquitylation K57 -1.174 _MGGEAPELALDPVPQDASTK(gl)K_
BAX Ubiquitylation K58 -1.718 -1.174 _MGGEAPELALDPVPQDASTKK(gl)_
BAX Ubiquitylation K64 0.708 1.306 _LSECLK(gl)R_
BCL2 Ubiquitylation K22 1.480 _YIHYK(gl)LSQR_
BRSK2 Phosphorylation S294 0.075 _SLPS(ph)LEDIDPDVLDSMHSLGCFR_
BRSK2 Phosphorylation S382 0.812 -1.070 _S(ph)MEVLSVTDGGSPVPAR_
BRSK2 Phosphorylation S393 -0.463 -1.217 _S(ph)M(ox)EVLSVTDGGS(ph)PVPAR_
BRSK2 Phosphorylation S423 -0.553 -0.633 _SISGASSGLSTS(ph)PLSSPR_
BRSK2 Phosphorylation S489 -0.354 -0.198 _NSFLGS(ph)PR_
CHAC1 Ubiquitylation K151 0.442 -0.540 _ALK(gl)YLNVR_
DNAJC10 Ubiquitylation K737 0.024 0.405 _VDCQAYAQTCQK(gl)AGIR_
EIF2AK3 Phosphorylation S715 0.832 _EHIEIIAPS(ph)PQR_
ITPR1 Ubiquitylation K529 1.377 _EK(gl)GGEGPLVR_
ITPR1 Phosphorylation S934 0.318 -0.802 _KQS(ph)VFSAPSLSAGASAAEPLDR_
ITPR1 Phosphorylation S937 -0.026 _KQSVFS(ph)APSLSAGASAAEPLDR_
ITPR1 Ubiquitylation K1534 -0.220 _TLAMVAK(gl)GR_
ITPR1 Phosphorylation S1598 1.165 0.362 _RDS(ph)VLAASR_
ITPR1 Phosphorylation S1832 0.650 0.560 _VAS(ph)FSIPGSSSR_
ITPR1 Ubiquitylation K2597 -0.819 _NK(gl)NLDWFPR_
ITPR1 Ubiquitylation K2628 -0.010 _ILQDK(gl)LNSTMK_
ITPR1 Phosphorylation S2670 1.132 1.555 _LGFVDVQNCIS(ph)R_
PML Ubiquitylation K394 0.515 0.360 _LQDLSSCITQGK(gl)DAAVSKK_
PML Phosphorylation S403 3.141 _KAS(ph)PEAASTPRDPIDVDLPEEAER_
PML Ubiquitylation K476 -0.403 -0.735 _GPSYGEDVSNTTTAQK(gl)R_
PML Phosphorylation S504 -0.198 -0.109 _S(ph)SPEQPRPSTSK_
PML Phosphorylation S505 -0.198 -0.109 _S(ph)SPEQPRPSTSK_
PML Phosphorylation S518 -1.632 -1.605 _AVS(ph)PPHLDGPPS(ph)PR_
PML Phosphorylation S527 -1.392 -1.605 _AVS(ph)PPHLDGPPS(ph)PR_
PML Phosphorylation S530 0.466 0.093 _S(ph)PVIGSEVFLPNSNHVASGAGEAEER_
PML Ubiquitylation K623 -0.784 _IDNETQK(gl)ISQLAAVNR_
TMBIM6 Ubiquitylation K65 -1.213 0.142 _K(gl)INFDALLK_
TNFRSF10B Ubiquitylation K369 -0.724 _KLGLMDNEIK(gl)VAK_
UBE2K Ubiquitylation K14 0.555 _EFK(gl)EVLKSEETSK_
UBE2K Ubiquitylation K72 -0.864 _IPETYPFNPPK(gl)VR_
UBE2K Ubiquitylation K142 -0.490 0.206 _QNPEMFK(gl)QTAR_
UBE2K Phosphorylation S158 -0.740 _LWAHVYAGAPVS(ph)SPEYTK_
UBE2K Ubiquitylation K164 -0.343 _LWAHVYAGAPVSSPEYTK(gl)K_
UBE2K Ubiquitylation K165 0.840 0.850 _K(gl)IENLCAMGFDR_


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