bioLOGIC Data » bioLOGIC CategoryView » bioLOGIC VennView » Experimental Details »

bioLOGIC Data

bioLOGIC Data


Exact search


Query: ATF4

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
W
[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
ATF4 0 2.296 -1.090 1.510

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
ATF4 Phosphorylation S69 0.252 _AGSSEWLAVDGLVS(ph)PSNNSK_
ATF4 Ubiquitylation K329 -0.035 _ADSLAK(gl)EIQYLK_
ATF4 Phosphorylation S248 0.569 -0.323 _SLPS(ph)PGVLCGSAR_
ATF4 Ubiquitylation K267 -1.961 _PYDPPGEK(gl)MVAAK_

Background Information for ATF4:


Pubmed-ATF4 »
Uniprot-ATF4 »
Biogrid-ATF4 »
ProteomicsDB-ATF4 »

Tumorportal-ATF4 »
COSMIC-ATF4 »
GenomeRNAi-ATF4 »
Genecards-ATF4


Protein-protein Interactions for ATF4
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ATF4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in ATF4
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members bZIP IPR004827 0


Protein complexes (CORUM database) featuring ATF4
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring ATF4
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005654 nucleoplasm Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0044267 cellular protein metabolic process Database 10.42
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members GO Category GO:0008022 protein C-terminus binding Database 1.43
Category members GO Category GO:0006094 gluconeogenesis Database 1.42
Category members GO Category GO:0030968 endoplasmic reticulum unfolded protein response Database 1.35
Category members GO Category GO:0006987 activation of signaling protein activity involved in unfolded protein response Database 1.26
Category members Pathway Pathway_147 REACTOME_UNFOLDED_PROTEIN_RESPONSE 0 1.08
Category members GO Category GO:0006366 transcription from RNA polymerase II promoter Database 0.96
Category members GO Category GO:0070059 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress Database 0.91
Category members Pathway Pathway_529 KEGG_NEUROTROPHIN_SIGNALING_PATHWAY 0 0.75
Category members Pathway Pathway_392 REACTOME_PERK_REGULATED_GENE_EXPRESSION 0 0.64
Category members GO Category GO:0003700 sequence-specific DNA binding transcription factor activity Database 0.63
Category members GO Category GO:0005815 microtubule organizing center Database 0.39
Category members Pathway Pathway_146 REACTOME_DIABETES_PATHWAYS 0 0.39
Category members Pathway Pathway_916 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_ATF6_ALPHA 0 0.33
Category members Pathway Pathway_915 REACTOME_ACTIVATION_OF_CHAPERONES_BY_ATF6_ALPHA 0 0.31
Category members GO Category GO:0045893 positive regulation of transcription, DNA-dependent Database 0.28
Category members Pathway Pathway_391 REACTOME_ACTIVATION_OF_GENES_BY_ATF4 0 0.23
Category members Pathway Pathway_232 KEGG_LONG_TERM_POTENTIATION 0 0.21
Category members GO Category GO:0005667 transcription factor complex Database 0.19
Category members GO Category GO:0006357 regulation of transcription from RNA polymerase II promoter Database 0.19
Category members GO Category GO:0043565 sequence-specific DNA binding Database 0.18
Category members Pathway Pathway_177 KEGG_PROSTATE_CANCER 0 0.13
Category members GO Category GO:0045944 positive regulation of transcription from RNA polymerase II promoter Database 0.13
Category members GO Category GO:0034976 response to endoplasmic reticulum stress Database 0.06
Category members GO Category GO:0032590 dendrite membrane Database 0.01
Category members Pathway Pathway_257 KEGG_GNRH_SIGNALING_PATHWAY 0 0
Category members Pathway Pathway_440 PID_FRA_PATHWAY 0 0
Category members Pathway Pathway_715 KEGG_MAPK_SIGNALING_PATHWAY 0 0
Category members GO Category GO:0006355 regulation of transcription, DNA-dependent Database 0
Category members GO Category GO:0006520 cellular amino acid metabolic process Database 0
Category members GO Category GO:0007214 gamma-aminobutyric acid signaling pathway Database 0
Category members GO Category GO:0043267 negative regulation of potassium ion transport Database 0
Category members GO Category GO:0043525 positive regulation of neuron apoptotic process Database 0


.

© Copyright Svejstrup Laboratory 2015