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Query: BAK1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
BAK1 1 1.620 0.710 0.160 -0.419 2.039

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence

Background Information for BAK1:


Pubmed-BAK1 »
Uniprot-BAK1 »
Biogrid-BAK1 »
ProteomicsDB-BAK1 »

Tumorportal-BAK1 »
COSMIC-BAK1 »
GenomeRNAi-BAK1 »
Genecards-BAK1


Protein-protein Interactions for BAK1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait MCL1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in BAK1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Blc2_fam IPR026298 0.14
Category members Bcl2-like IPR002475 0.05


Protein complexes (CORUM database) featuring BAK1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 5823 MCL1-BAK1 complex Database 0


Categories featuring BAK1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members Pathway Pathway_837 REACTOME_APOPTOSIS 0 2.39
Category members GO Category GO:0006915 apoptotic process Database 2.12
Category members GO Category GO:0051087 chaperone binding Database 1.69
Category members GO Category GO:0005739 mitochondrion Database 1.67
Category members GO Category GO:0031072 heat shock protein binding Database 1.59
Category members GO Category GO:0051881 regulation of mitochondrial membrane potential Database 1.57
Category members GO Category GO:0046930 pore complex Database 1.57
Category members GO Category GO:0032469 endoplasmic reticulum calcium ion homeostasis Database 1.26
Category members GO Category GO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage Database 1.14
Category members GO Category GO:0070059 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress Database 0.91
Category members GO Category GO:0042981 regulation of apoptotic process Database 0.79
Category members GO Category GO:0042493 response to drug Database 0.66
Category members GO Category GO:0010248 establishment or maintenance of transmembrane electrochemical gradient Database 0.63
Category members GO Category GO:0048597 post-embryonic camera-type eye morphogenesis Database 0.63
Category members GO Category GO:0005783 endoplasmic reticulum Database 0.62
Category members Pathway Pathway_754 SA_PROGRAMMED_CELL_DEATH 0 0.61
Category members GO Category GO:0016020 membrane Database 0.52
Category members GO Category GO:0010332 response to gamma radiation Database 0.52
Category members GO Category GO:0034644 cellular response to UV Database 0.49
Category members GO Category GO:0005741 mitochondrial outer membrane Database 0.46
Category members GO Category GO:0046902 regulation of mitochondrial membrane permeability Database 0.33
Category members GO Category GO:0005622 intracellular Database 0.32
Category members GO Category GO:0002262 myeloid cell homeostasis Database 0.3
Category members GO Category GO:0032471 negative regulation of endoplasmic reticulum calcium ion concentration Database 0.3
Category members GO Category GO:0008285 negative regulation of cell proliferation Database 0.28
Category members GO Category GO:0046982 protein heterodimerization activity Database 0.28
Category members GO Category GO:0008053 mitochondrial fusion Database 0.27
Category members GO Category GO:0002352 B cell negative selection Database 0.26
Category members GO Category GO:0042802 identical protein binding Database 0.26
Category members GO Category GO:0043065 positive regulation of apoptotic process Database 0.26
Category members GO Category GO:0031307 integral to mitochondrial outer membrane Database 0.24
Category members Pathway Pathway_383 PID_P53_DOWNSTREAM_PATHWAY 0 0.23
Category members GO Category GO:0001783 B cell apoptotic process Database 0.23
Category members GO Category GO:0033137 negative regulation of peptidyl-serine phosphorylation Database 0.21
Category members GO Category GO:0042542 response to hydrogen peroxide Database 0.19
Category members GO Category GO:0001836 release of cytochrome c from mitochondria Database 0.18
Category members GO Category GO:0070242 thymocyte apoptotic process Database 0.13
Category members GO Category GO:0043496 regulation of protein homodimerization activity Database 0.12
Category members Pathway Pathway_200 PID_P73PATHWAY 0 0.11
Category members GO Category GO:0051726 regulation of cell cycle Database 0.11
Category members GO Category GO:0045471 response to ethanol Database 0.1
Category members GO Category GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process Database 0.08
Category members GO Category GO:0043497 regulation of protein heterodimerization activity Database 0.07
Category members GO Category GO:0008283 cell proliferation Database 0.06
Category members GO Category GO:0048872 homeostasis of number of cells Database 0.05
Category members GO Category GO:0009620 response to fungus Database 0.02
Category members Pathway Pathway_386 ST_FAS_SIGNALING_PATHWAY 0 0.02
Category members GO Category GO:0001782 B cell homeostasis Database 0.02
Category members GO Category GO:0031100 organ regeneration Database 0.01
Category members Pathway Pathway_1012 BIOCARTA_MITOCHONDRIA_PATHWAY 0 0
Category members Pathway Pathway_990 REACTOME_INTRINSIC_PATHWAY_FOR_APOPTOSIS 0 0
Category members GO Category GO:0001776 leukocyte homeostasis Database 0
Category members GO Category GO:0001974 blood vessel remodeling Database 0
Category members GO Category GO:0007420 brain development Database 0
Category members GO Category GO:0007568 aging Database 0
Category members GO Category GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c Database 0
Category members GO Category GO:0010225 response to UV-C Database 0
Category members GO Category GO:0010524 positive regulation of calcium ion transport into cytosol Database 0
Category members GO Category GO:0010629 negative regulation of gene expression Database 0
Category members GO Category GO:0014070 response to organic cyclic compound Database 0
Category members GO Category GO:0031018 endocrine pancreas development Database 0
Category members GO Category GO:0031966 mitochondrial membrane Database 0
Category members GO Category GO:0035108 limb morphogenesis Database 0
Category members GO Category GO:0042803 protein homodimerization activity Database 0
Category members GO Category GO:0044346 fibroblast apoptotic process Database 0
Category members GO Category GO:0045862 positive regulation of proteolysis Database 0
Category members GO Category GO:0046872 metal ion binding Database 0
Category members GO Category GO:0051400 BH domain binding Database 0
Category members GO Category GO:0060068 vagina development Database 0
Category members GO Category GO:0071260 cellular response to mechanical stimulus Database 0


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