Results for the Category
activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c
(GO:0008635)
| RNAi screen result | RNAPII IP (MG132) | CSB IP | CSB IP (MG132) | Chrom. | Chrom. (MG132) | Ubi /Phospo | Ubi /Phospho (MG132) |
| W | |||||||
| Gene name | MGoogle Score | RNAi high | RNAi low | RNAPII-IP (MG132) | CSB-IP | CSB-IP (MG132) | Chrom. | Chrom. (MG132) |
|---|---|---|---|---|---|---|---|---|
| BAK1 | 1 | 0.710 | 0.160 | -0.419 | 2.039 | |||
| BAX | 0 | 1.590 | -1.170 | 0.811 | 0.359 | |||
| CASP3 | 0 | 0.570 | -0.390 | |||||
| CASP7 | 0 | 0.130 | -0.130 | |||||
| CYCS | 0 | -0.020 | -0.350 | 0.711 | 0.320 | |||
| DIABLO | 0 | 0.740 | -0.290 | 0.517 | 0.500 | |||
| DIABLO | 0 | 0.740 | -0.290 | -0.061 |
| Gene name | PTM type | PTM site | UV | UV (MG132) | Sequence |
|---|---|---|---|---|---|
| BAX | Ubiquitylation | K57 | -1.174 | _MGGEAPELALDPVPQDASTK(gl)K_ | |
| BAX | Ubiquitylation | K58 | -1.718 | -1.174 | _MGGEAPELALDPVPQDASTKK(gl)_ |
| BAX | Ubiquitylation | K64 | 0.708 | 1.306 | _LSECLK(gl)R_ |
| CASP3 | Ubiquitylation | K11 | -0.053 | -0.687 | _(ac)MENTENSVDSK(gl)SIK_ |
| CASP3 | Ubiquitylation | K14 | -0.455 | -0.687 | _SIK(gl)NLEPK_ |
| CASP3 | Ubiquitylation | K57 | -0.304 | -1.817 | _NFHK(gl)STGMTSR_ |
| CASP3 | Ubiquitylation | K82 | -0.268 | -0.605 | _NLK(gl)YEVR_ |
| CASP7 | Phosphorylation | S16 | 0.096 | -0.112 | _(ac)ADDQGCIEEQGVEDS(ph)ANEDSVDAKPDR_ |
| CASP7 | Ubiquitylation | K80 | 0.580 | -0.044 | _NFDK(gl)VTGMGVR_ |
| CYCS | Ubiquitylation | K40 | -2.265 | _K(gl)TGQAPGYSYTAANK(gl)NK_ | |
| CYCS | Ubiquitylation | K54 | -0.872 | -1.922 | _K(gl)TGQAPGYSYTAANK(gl)NK_ |
| CYCS | Ubiquitylation | K56 | -0.872 | -1.922 | _TGQAPGYSYTAANKNK(gl)_ |
| CYCS | Ubiquitylation | K101 | -1.859 | _ADLIAYLKK(gl)_ |
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