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Query: BRSK2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
BRSK2 0 0.887 1.070 -0.640

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
BRSK2 Phosphorylation S294 0.075 _SLPS(ph)LEDIDPDVLDSMHSLGCFR_
BRSK2 Phosphorylation S489 -0.354 -0.198 _NSFLGS(ph)PR_
BRSK2 Phosphorylation S423 -0.553 -0.633 _SISGASSGLSTS(ph)PLSSPR_
BRSK2 Phosphorylation S382 0.812 -1.070 _S(ph)MEVLSVTDGGSPVPAR_
BRSK2 Phosphorylation S393 -0.463 -1.217 _S(ph)M(ox)EVLSVTDGGS(ph)PVPAR_

Background Information for BRSK2:


Pubmed-BRSK2 »
Uniprot-BRSK2 »
Biogrid-BRSK2 »
ProteomicsDB-BRSK2 »

Tumorportal-BRSK2 »
COSMIC-BRSK2 »
GenomeRNAi-BRSK2 »
Genecards-BRSK2


Protein-protein Interactions for BRSK2
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait RRBP1 Cat. description Hein, Mann, Cell 2015


Protein Domains in BRSK2
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Kinase-like_dom IPR011009 0.03
Category members Prot_kinase_dom IPR000719 0
Category members Ser-Thr/Tyr_kinase_cat_dom IPR001245 0
Category members Ser/Thr_dual-sp_kinase IPR002290 0
Category members Tyr_kinase_cat_dom IPR020635 0


Protein complexes (CORUM database) featuring BRSK2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring BRSK2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members GO Category GO:0007067 mitosis Database 2.23
Category members GO Category GO:0030010 establishment of cell polarity Database 0.91
Category members GO Category GO:0070059 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress Database 0.91
Category members GO Category GO:0005813 centrosome Database 0.75
Category members GO Category GO:0004674 protein serine/threonine kinase activity Database 0.66
Category members GO Category GO:0005783 endoplasmic reticulum Database 0.62
Category members Pathway Pathway_1142 PID_LKB1_PATHWAY 0 0.6
Category members GO Category GO:0048471 perinuclear region of cytoplasm Database 0.39
Category members GO Category GO:0019901 protein kinase binding Database 0.37
Category members GO Category GO:0000086 G2/M transition of mitotic cell cycle Database 0.33
Category members GO Category GO:0031532 actin cytoskeleton reorganization Database 0.29
Category members GO Category GO:0016301 kinase activity Database 0.23
Category members GO Category GO:0006887 exocytosis Database 0.2
Category members GO Category GO:0004672 protein kinase activity Database 0.19
Category members GO Category GO:0018105 peptidyl-serine phosphorylation Database 0.18
Category members GO Category GO:0007409 axonogenesis Database 0.13
Category members GO Category GO:0006468 protein phosphorylation Database 0.04
Category members GO Category GO:0050321 tau-protein kinase activity Database 0.04
Category members GO Category GO:0004713 protein tyrosine kinase activity Database 0.01
Category members GO Category GO:0000287 magnesium ion binding Database 0
Category members GO Category GO:0016772 transferase activity, transferring phosphorus-containing groups Database 0
Category members GO Category GO:0030182 neuron differentiation Database 0
Category members GO Category GO:0048812 neuron projection morphogenesis Database 0
Category members GO Category GO:0061178 regulation of insulin secretion involved in cellular response to glucose stimulus Database 0


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