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Query: DNAJC10

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
DNAJC10 1 4.858 -1.750 3.210 0.769 -0.495 -0.158 0.513 0.706

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
DNAJC10 Ubiquitylation K737 0.024 0.405 _VDCQAYAQTCQK(gl)AGIR_

Background Information for DNAJC10:





Protein-protein Interactions for DNAJC10

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CDC42 Cat. description Hein, Mann, Cell 2015
Category members IP bait CENPE Cat. description Hein, Mann, Cell 2015
Category members IP bait MIS12 Cat. description Hein, Mann, Cell 2015
Category members IP bait DNAJC10 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in DNAJC10

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Thioredoxin_domain IPR013766 0.49
Category members DnaJ_domain IPR001623 0.3
Category members Thioredoxin-like_fold IPR012336 0.16


Protein complexes (CORUM database) featuring DNAJC10

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring DNAJC10

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members DDR Literature pubmedid:19647519 Paulsen et al., 2009 siRNA screen for g-H2A.x phosphorylation 3.6
Category members GO Category GO:0051087 chaperone binding Database 1.69
Category members GO Category GO:0070059 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress Database 0.91
Category members GO Category GO:0006662 glycerol ether metabolic process Database 0.79
Category members GO Category GO:0005783 endoplasmic reticulum Database 0.62
Category members GO Category GO:0030433 ER-associated ubiquitin-dependent protein catabolic process Database 0.33
Category members GO Category GO:0030544 Hsp70 protein binding Database 0.1
Category members GO Category GO:0034976 response to endoplasmic reticulum stress Database 0.06
Category members GO Category GO:0045454 cell redox homeostasis Database 0.05
Category members GO Category GO:0015036 disulfide oxidoreductase activity Database 0.05
Category members GO Category GO:0001933 negative regulation of protein phosphorylation Database 0.04
Category members GO Category GO:0001671 ATPase activator activity Database 0.03
Category members GO Category GO:0005788 endoplasmic reticulum lumen Database 0
Category members GO Category GO:0015035 protein disulfide oxidoreductase activity Database 0
Category members GO Category GO:0016671 oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor Database 0
Category members GO Category GO:0032781 positive regulation of ATPase activity Database 0
Category members GO Category GO:0034663 endoplasmic reticulum chaperone complex Database 0
Category members GO Category GO:0051117 ATPase binding Database 0
Category members GO Category GO:0051787 misfolded protein binding Database 0


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