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Query: UBE2K

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
UBE2K 0 1.550 -0.480 0.600

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
UBE2K Ubiquitylation K165 0.840 0.850 _K(gl)IENLCAMGFDR_
UBE2K Ubiquitylation K142 -0.490 0.206 _QNPEMFK(gl)QTAR_
UBE2K Phosphorylation S158 -0.740 _LWAHVYAGAPVS(ph)SPEYTK_
UBE2K Ubiquitylation K14 0.555 _EFK(gl)EVLKSEETSK_
UBE2K Ubiquitylation K72 -0.864 _IPETYPFNPPK(gl)VR_
UBE2K Ubiquitylation K164 -0.343 _LWAHVYAGAPVSSPEYTK(gl)K_

Background Information for UBE2K:


Pubmed-UBE2K »
Uniprot-UBE2K »
Biogrid-UBE2K »
ProteomicsDB-UBE2K »

Tumorportal-UBE2K »
COSMIC-UBE2K »
GenomeRNAi-UBE2K »
Genecards-UBE2K


Protein-protein Interactions for UBE2K
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait UBE2K Cat. description Hein, Mann, Cell 2015


Protein Domains in UBE2K
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members UBA/Ts_N IPR000449 0.34
Category members UBA-like IPR009060 0.17
Category members UBA/transl_elong_EF1B_N_euk IPR015940 0.04
Category members UBQ-conjugat_E2 IPR000608 0
Category members UBQ-conjugating_enzyme/RWD IPR016135 0


Protein complexes (CORUM database) featuring UBE2K
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring UBE2K
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members Pathway Pathway_621 REACTOME_ADAPTIVE_IMMUNE_SYSTEM 0 4.72
Category members GO Category GO:0006511 ubiquitin-dependent protein catabolic process Database 3.57
Category members Pathway Pathway_458 REACTOME_IMMUNE_SYSTEM 0 3
Category members Pathway Pathway_764 REACTOME_CLASS_I_MHC_MEDIATED_ANTIGEN_PROCESSING_PRESENTATION 0 2.56
Category members GO Category GO:0031625 ubiquitin protein ligase binding Database 2.54
Category members Pathway Pathway_888 KEGG_UBIQUITIN_MEDIATED_PROTEOLYSIS 0 2.22
Category members Pathway Pathway_832 REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION 0 1.58
Category members GO Category GO:0070059 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress Database 0.91
Category members Pathway Pathway_460 REACTOME_INNATE_IMMUNE_SYSTEM 0 0.29
Category members GO Category GO:0004842 ubiquitin-protein ligase activity Database 0.24
Category members GO Category GO:0032434 regulation of proteasomal ubiquitin-dependent protein catabolic process Database 0.13
Category members Pathway Pathway_484 REACTOME_RIG_I_MDA5_MEDIATED_INDUCTION_OF_IFN_ALPHA_BETA_PATHWAYS 0 0.06
Category members Pathway Pathway_785 REACTOME_NEGATIVE_REGULATORS_OF_RIG_I_MDA5_SIGNALING 0 0
Category members GO Category GO:0016881 acid-amino acid ligase activity Database 0
Category members GO Category GO:0034450 ubiquitin-ubiquitin ligase activity Database 0
Category members GO Category GO:0070936 protein K48-linked ubiquitination Database 0


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