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Query: DAPK1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
DAPK1 0 -0.173 -0.090 -0.480 -1.111

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
DAPK1 Ubiquitylation K939 0.937 0.001 _LFVLDAGASGSK(gl)DMK_

Background Information for DAPK1:


Pubmed-DAPK1 »
Uniprot-DAPK1 »
Biogrid-DAPK1 »
ProteomicsDB-DAPK1 »

Tumorportal-DAPK1 »
COSMIC-DAPK1 »
GenomeRNAi-DAPK1 »
Genecards-DAPK1


Protein-protein Interactions for DAPK1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ERP44 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait IFI30 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in DAPK1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members P-loop_NTPase IPR027417 2.83
Category members DEATH-like_dom IPR011029 1.15
Category members Death_domain IPR000488 0.08
Category members Kinase-like_dom IPR011009 0.03
Category members Prot_kinase_dom IPR000719 0
Category members Ser-Thr/Tyr_kinase_cat_dom IPR001245 0
Category members Ankyrin_rpt IPR002110 0
Category members Ser/Thr_dual-sp_kinase IPR002290 0
Category members LipoPS_kinase IPR010440 0
Category members RIO-like_kinase IPR018934 0
Category members Tyr_kinase_cat_dom IPR020635 0
Category members Ankyrin_rpt-contain_dom IPR020683 0


Protein complexes (CORUM database) featuring DAPK1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring DAPK1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members Pathway Pathway_837 REACTOME_APOPTOSIS 0 2.39
Category members GO Category GO:0015629 actin cytoskeleton Database 2.22
Category members GO Category GO:0006915 apoptotic process Database 2.12
Category members Pathway Pathway_1016 REACTOME_ROLE_OF_DCC_IN_REGULATING_APOPTOSIS 0 0.87
Category members GO Category GO:0042981 regulation of apoptotic process Database 0.79
Category members GO Category GO:0005516 calmodulin binding Database 0.74
Category members GO Category GO:0004674 protein serine/threonine kinase activity Database 0.66
Category members GO Category GO:0043066 negative regulation of apoptotic process Database 0.6
Category members GO Category GO:0016020 membrane Database 0.52
Category members GO Category GO:0017148 negative regulation of translation Database 0.34
Category members Pathway Pathway_795 REACTOME_REGULATION_OF_APOPTOSIS 0 0.31
Category members GO Category GO:0042802 identical protein binding Database 0.26
Category members GO Category GO:0043065 positive regulation of apoptotic process Database 0.26
Category members GO Category GO:0046777 protein autophosphorylation Database 0.23
Category members GO Category GO:0004672 protein kinase activity Database 0.19
Category members Pathway Pathway_388 KEGG_BLADDER_CANCER 0 0.16
Category members Pathway Pathway_537 PID_IFNG_PATHWAY 0 0.11
Category members GO Category GO:0003824 catalytic activity Database 0.11
Category members GO Category GO:0006468 protein phosphorylation Database 0.04
Category members GO Category GO:0071346 cellular response to interferon-gamma Database 0.04
Category members GO Category GO:0004713 protein tyrosine kinase activity Database 0.01
Category members Pathway Pathway_24 KEGG_PATHWAYS_IN_CANCER 0 0
Category members Pathway Pathway_640 PID_NETRIN_PATHWAY 0 0
Category members GO Category GO:0004683 calmodulin-dependent protein kinase activity Database 0
Category members GO Category GO:0007165 signal transduction Database 0
Category members GO Category GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors Database 0
Category members GO Category GO:0009103 lipopolysaccharide biosynthetic process Database 0
Category members GO Category GO:0010506 regulation of autophagy Database 0
Category members GO Category GO:0016772 transferase activity, transferring phosphorus-containing groups Database 0
Category members GO Category GO:0016773 phosphotransferase activity, alcohol group as acceptor Database 0
Category members GO Category GO:0035556 intracellular signal transduction Database 0


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