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Query: BAG3

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
BAG3 1 4.168 0.180 -0.820

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
BAG3 Phosphorylation S194 -0.402 -0.523 _S(ph)SLGSHQLPR_
BAG3 Phosphorylation S173 -0.549 -0.580 _SQS(ph)PAASDCSSSSSSASLPSSGR_
BAG3 Phosphorylation S195 0.244 -0.933 _SS(ph)LGSHQLPR_
BAG3 Phosphorylation S291 0.973 -1.061 _SSTPLHSPS(ph)PIR_
BAG3 Phosphorylation S289 4.691 -1.292 _SSTPLHS(ph)PSPIR_
BAG3 Phosphorylation S385 -3.389 -1.522 _VPPAPVPCPPPS(ph)PGPSAVPS(ph)SPK_
BAG3 Phosphorylation S381 -1.826 _VPPAPVPCPPPSPGPS(ph)AVPS(ph)SPK_
BAG3 Phosphorylation S377 -2.611 -2.836 _VPPAPVPCPPPS(ph)PGPSAVPSSPK_
BAG3 Phosphorylation S386 -3.389 -3.269 _VPPAPVPCPPPS(ph)PGPSAVPSS(ph)PK_

Background Information for BAG3:





Protein-protein Interactions for BAG3

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait BAG3 Cat. description Hein, Mann, Cell 2015
Category members IP bait FAM83D Cat. description Hein, Mann, Cell 2015
Category members IP bait SEC16A Cat. description Hein, Mann, Cell 2015
Category members IP bait CRYAB Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FAM189B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HSPB6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HSPB8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait KCND2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait KLHL34 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait METTL21A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait P4HA2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PDLIM7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PNPLA5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RPTOR Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SLC27A3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SPINT2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in BAG3

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members WW_dom IPR001202 1.15
Category members BAG_domain IPR003103 0


Protein complexes (CORUM database) featuring BAG3

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 6052 BAG3-HSC70-HSPB8-CHIP complex Database 0.32


Categories featuring BAG3

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0006457 protein folding Database 4.93
Category members GO Category GO:0051087 chaperone binding Database 1.69
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0043066 negative regulation of apoptotic process Database 0.6
Category members GO Category GO:0032403 protein complex binding Database 0.49
Category members GO Category GO:0030018 Z disc Database 0.32
Category members Disease phenotype Familial_isolated_dilated_cardiomyopathy Familial isolated dilated cardiomyopathy Database 0.08
Category members GO Category GO:0043005 neuron projection Database 0.08
Category members GO Category GO:0050821 protein stabilization Database 0.04
Category members GO Category GO:0007420 brain development Database 0
Category members GO Category GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors Database 0
Category members GO Category GO:0010664 negative regulation of striated muscle cell apoptotic process Database 0
Category members GO Category GO:0021510 spinal cord development Database 0
Category members GO Category GO:0071260 cellular response to mechanical stimulus Database 0


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