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Results for the Category
Autosomal dominant nonsyndromic sensorineural deafness type DFNA
(Autosomal_dominant_nonsyndromic_sensorineural_deafness_type_DFNA)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
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Protein Results:

 Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
EYA4 2 -0.120 0.100
MYH9 1 -1.530 2.620 0.366 -0.040 -0.375 0.136 -0.183
MYO6 1 -1.580 2.560 0.037 0.700 0.607
MYO6 1 -1.580 2.560 -0.533
COCH 0 0.370 -0.760
MYH14 0 -0.990 1.070 0.436 -0.296 0.144 -0.154
WFS1 0 -0.390 0.420 -0.793 -0.234
TJP2 0 0.160 0.070 -1.237 -1.460
TJP2 0 0.160 0.070 0.144 0.035 0.024
SIX1 0 1.730 -1.230 -0.334 0.495
DIAPH1 0 0.480 -0.910 -0.053 -0.130 0.367
DIAPH3 0 0.980 -0.460
CCDC50 0 0.170 0.180
MYO1A 0 -0.730 0.450 0.137 0.249 1.311 0.007
DIABLO 0 0.740 -0.290 0.517 0.500
DIABLO 0 0.740 -0.290 -0.061

PTM Sites:

 Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
CCDC50 Ubiquitylation K107 -0.119 0.640 _IQEK(gl)KDEDIAR_
CCDC50 Ubiquitylation K108 -0.496 0.411 _IQEKK(gl)DEDIAR_
CCDC50 Ubiquitylation K119 0.480 0.910 _LLQEK(gl)ELQEEK_
CCDC50 Ubiquitylation K129 -0.775 -0.097 _K(gl)HFPEFPATR_
CCDC50 Ubiquitylation K152 0.029 0.809 _AYADSYYYEDGGMK(gl)PR_
CCDC50 Ubiquitylation K181 0.540 _K(gl)LQEEELLATQVDMR_
CCDC50 Ubiquitylation K214 0.240 _LLM(ox)AEEK(gl)K_
CCDC50 Ubiquitylation K215 0.344 1.213 _LLMAEEKK(gl)_
CCDC50 Ubiquitylation K232 -0.174 -0.504 _K(gl)QDPEWKPK_
CCDC50 Ubiquitylation K238 -0.393 -0.442 _KQDPEWK(gl)PK_
CCDC50 Ubiquitylation K240 -0.435 -0.884 _KQDPEWKPK(gl)TAK_
COCH Ubiquitylation K344 0.392 _YVK(gl)PLVQK_
DIAPH1 Phosphorylation S22 0.053 0.108 _S(ph)PDELPSAGGDGGK_
DIAPH1 Ubiquitylation K503 0.696 0.481 _HELQVEMK(gl)K_
DIAPH1 Ubiquitylation K504 0.243 0.685 _HELQVEM(ox)KK(gl)_
DIAPH3 Ubiquitylation K275 -0.804 _SLSLLAK(gl)AVDPR_
EYA4 Phosphorylation S4 2.607 2.311 _(ac)M(ox)EDS(ph)QDLNEQSVK_
EYA4 Phosphorylation S367 -1.041 -1.090 _NNPS(ph)PPPDSDLER_
EYA4 Ubiquitylation K513 -0.108 _NNVGGLLGPAK(gl)R_
EYA4 Ubiquitylation K587 -1.219 _IGK(gl)ESCFER_
MYH9 Ubiquitylation K66 0.545 _VK(gl)VNKDDIQK_
MYH9 Ubiquitylation K403 0.390 0.869 _DYVQK(gl)AQTK_
MYH9 Ubiquitylation K682 -0.508 _AGK(gl)LDPHLVLDQLR_
MYH9 Ubiquitylation K760 0.409 0.964 _IGQSK(gl)VFFR_
MYH9 Ubiquitylation K821 -0.339 _NCAAYLK(gl)LR_
MYH9 Ubiquitylation K856 -1.336 _EEELVK(gl)VR_
MYH9 Ubiquitylation K860 -0.570 0.212 _VREK(gl)QLAAENR_
MYH9 Ubiquitylation K1274 0.036 _VRTELADK(gl)VTK_
MYH9 Ubiquitylation K1277 0.081 _TELADKVTK(gl)_
MYH9 Ubiquitylation K1413 0.288 _VAAYDKLEK(gl)TK_
MYH9 Ubiquitylation K1415 0.790 _VAAYDKLEKTK(gl)_
MYH9 Phosphorylation S1943 0.168 0.290 _KGAGDGS(ph)DEEVDGKADGAEAK_
MYO1A Ubiquitylation K303 -0.725 _IKDK(gl)NELK_
MYO1A Ubiquitylation K354 1.472 _DALAK(gl)NLYSR_
MYO1A Ubiquitylation K588 -0.892 _NLQTK(gl)NPNYIR_
MYO1A Ubiquitylation K972 0.034 _ALYPSSVGQPFQGAYLEINK(gl)NPK_
MYO1A Ubiquitylation K980 1.046 _LK(gl)DAIEEK_
MYO6 Phosphorylation S266 0.008 _LHLS(ph)SPDNFR_
MYO6 Phosphorylation S267 -0.106 0.501 _LHLSS(ph)PDNFR_
MYO6 Ubiquitylation K285 0.079 _YFANK(gl)ETDKQILQNR_
MYO6 Ubiquitylation K408 0.078 _GTVIK(gl)VPLKVEQANNAR_
MYO6 Ubiquitylation K634 0.366 _ELFESSTNNNKDTKQK(gl)_
MYO6 Ubiquitylation K993 -0.079 1.133 _QK(gl)EEESQQQAVLEQERR_
MYO6 Ubiquitylation K1053 -1.790 _NDGTRPK(gl)MTPEQMAK_
MYO6 Ubiquitylation K1077 -0.135 0.805 _GPAVLATK(gl)AAAGTK_
MYO6 Ubiquitylation K1089 0.440 1.326 _YDLSK(gl)WK_
MYO6 Ubiquitylation K1120 0.732 0.435 _LK(gl)VYHAWK_
MYO6 Ubiquitylation K1126 0.296 _VYHAWK(gl)SK_
MYO6 Ubiquitylation K1142 -1.182 -0.570 _NTETEQRAPK(gl)SVTDYAQQNPAAQIPAR_
MYO6 Ubiquitylation K1184 -1.200 -0.624 _IPFIRPADQYK(gl)DPQSK_
SIX1 Ubiquitylation K53 0.475 _AK(gl)AVVAFHR_
TJP2 Phosphorylation S161 -0.169 -0.024 _VQVAALQAS(ph)PPLDQDDR_
TJP2 Phosphorylation S205 0.118 0.563 _SWEDS(ph)PER_
TJP2 Phosphorylation S275 0.891 0.690 _GRS(ph)IDQDYER_
TJP2 Phosphorylation S297 0.478 0.579 _AYS(ph)PEYR_
TJP2 Phosphorylation S446 0.631 _SFS(ph)PEER_
TJP2 Phosphorylation S471 -0.863 0.159 _ERPS(ph)SREDTPSR_
TJP2 Phosphorylation S472 -0.715 0.193 _ERPSS(ph)REDTPSR_
TJP2 Ubiquitylation K506 -0.355 -0.981 _STGDIAGTVVPETNK(gl)EPR_
TJP2 Ubiquitylation K520 -1.549 _YQEEPPAPQPK(gl)AAPR_
TJP2 Ubiquitylation K800 -0.173 0.403 _DAGSEK(gl)STGVVR_
TJP2 Phosphorylation S992 -0.733 _SSEPVQHEES(ph)IRKPSPEPR_
TJP2 Phosphorylation S997 -1.075 -0.616 _SSEPVQHEESIRKPS(ph)PEPR_
TJP2 Phosphorylation S1017 -1.379 -1.918 _DNS(ph)PPPAFKPEPPK_
TJP2 Ubiquitylation K1047 -0.374 -0.833 _SYEYK(gl)SNPSAVAGNETPGASTK_
TJP2 Phosphorylation S1187 0.856 _GS(ph)YGSDAEEEEYRQQLSEHSK_
TJP2 Phosphorylation S1190 0.754 0.727 _GSYGS(ph)DAEEEEYRQQLSEHSK_
WFS1 Phosphorylation S32 1.184 1.098 _LNATAS(ph)LEQER_
WFS1 Ubiquitylation K143 0.703 _EAVK(gl)LLR_


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