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Query: CSNK1A1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
CSNK1A1 1 2.290 0.080 -0.140 2.048 -0.562 0.195 -0.389 0.187

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
CSNK1A1 Ubiquitylation K18 0.772 _AEFIVGGKYK(gl)_
CSNK1A1 Ubiquitylation K225 0.039 0.502 _TSLPWQGLK(gl)AATK_
CSNK1A1 Ubiquitylation K304 -0.489 0.015 _QK(gl)AAQQAASSSGQGQQAQTPTGK_
CSNK1A1 Ubiquitylation K8 -0.342 -0.408 _(ac)ASSSGSK(gl)AEFIVGGK_

Background Information for CSNK1A1:





Protein-protein Interactions for CSNK1A1

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait AXIN1 Cat. description Hein, Mann, Cell 2015
Category members IP bait CLTC Cat. description Hein, Mann, Cell 2015
Category members IP bait FAM83D Cat. description Hein, Mann, Cell 2015
Category members IP bait FAM83H Cat. description Hein, Mann, Cell 2015
Category members IP bait GTSE1 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYO18A Cat. description Hein, Mann, Cell 2015
Category members IP bait SEC16A Cat. description Hein, Mann, Cell 2015
Category members IP bait SEC24C Cat. description Hein, Mann, Cell 2015
Category members IP bait USO1 Cat. description Hein, Mann, Cell 2015
Category members IP bait XRCC6 Cat. description Hein, Mann, Cell 2015
Category members IP bait ARHGAP22 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C1orf111 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C7orf45 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CSNK1A1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FAM170A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MDM4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NCKIPSD Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait POTEB Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait POTEC Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SNX24 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TEX264 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in CSNK1A1

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Kinase-like_dom IPR011009 0.03
Category members Prot_kinase_dom IPR000719 0
Category members Ser-Thr/Tyr_kinase_cat_dom IPR001245 0
Category members Ser/Thr_dual-sp_kinase IPR002290 0
Category members Tyr_kinase_cat_dom IPR020635 0


Protein complexes (CORUM database) featuring CSNK1A1

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring CSNK1A1

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members DDR Literature pubmedid:24332808 Marechal et al., 2014 RPA-mediated recruitment INF
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members GO Category GO:0016607 nuclear speck Database 4.84
Category members Pathway Pathway_807 REACTOME_SIGNALING_BY_WNT 0 2.74
Category members Pathway Pathway_416 PID_P53_REGULATION_PATHWAY 0 2.29
Category members GO Category GO:0007067 mitosis Database 2.23
Category members Pathway Pathway_1023 PID_NFAT_3PATHWAY 0 1.46
Category members Pathway Pathway_1257 REACTOME_CTNNB1_PHOSPHORYLATION_CASCADE 0 1.21
Category members Pathway Pathway_118 PID_FOXO_PATHWAY 0 0.97
Category members GO Category GO:0005813 centrosome Database 0.75
Category members GO Category GO:0004674 protein serine/threonine kinase activity Database 0.66
Category members Pathway Pathway_840 ST_WNT_BETA_CATENIN_PATHWAY 0 0.6
Category members GO Category GO:0000777 condensed chromosome kinetochore Database 0.32
Category members GO Category GO:0004672 protein kinase activity Database 0.19
Category members Pathway Pathway_1141 BIOCARTA_P35ALZHEIMERS_PATHWAY 0 0.19
Category members Pathway Pathway_759 BIOCARTA_P53HYPOXIA_PATHWAY 0 0.18
Category members GO Category GO:0005847 mRNA cleavage and polyadenylation specificity factor complex Database 0.11
Category members GO Category GO:0016055 Wnt signaling pathway Database 0.11
Category members Pathway Pathway_984 PID_HEDGEHOG_GLI_PATHWAY 0 0.1
Category members GO Category GO:0007166 cell surface receptor signaling pathway Database 0.1
Category members Pathway Pathway_679 KEGG_WNT_SIGNALING_PATHWAY 0 0.09
Category members Pathway Pathway_417 PID_WNT_NONCANONICAL_PATHWAY 0 0.09
Category members Pathway Pathway_941 BIOCARTA_WNT_PATHWAY 0 0.08
Category members GO Category GO:0006468 protein phosphorylation Database 0.04
Category members Pathway Pathway_1151 KEGG_HEDGEHOG_SIGNALING_PATHWAY 0 0.04
Category members Pathway Pathway_942 PID_PS1_PATHWAY 0 0.03
Category members Pathway Pathway_386 ST_FAS_SIGNALING_PATHWAY 0 0.02
Category members Pathway Pathway_1175 PID_BETA_CATENIN_DEG_PATHWAY 0 0.01
Category members GO Category GO:0004713 protein tyrosine kinase activity Database 0.01
Category members Pathway Pathway_290 WNT_SIGNALING 0 0
Category members Pathway Pathway_641 BIOCARTA_NFAT_PATHWAY 0 0
Category members GO Category GO:0007165 signal transduction Database 0
Category members GO Category GO:0016772 transferase activity, transferring phosphorus-containing groups Database 0


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