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Results for the Category
PID_FOXO_PATHWAY
(Pathway_118)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
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Protein Results:

 Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
FOXO3 2 -0.410 -0.120
CAT 2 2.260 -1.180 1.895 -0.238
PLK1 2 3.098 -0.387 0.212 -1.949 -0.610
MAPK9 1 0.110 -0.490
YWHAE 1 0.440 -0.380 1.095 -0.160
YWHAE 1 0.440 -0.380 1.129 0.621 0.321
SOD2 1 -0.340 0.140 2.161 -0.330
CSNK1A1 1 0.080 -0.140 2.048 -0.562 0.195 -0.389 0.187
KAT2B 1 -0.980 2.090
RAN 1 0.795 0.949 -0.688 0.566 0.288
YWHAQ 1 -0.260 0.670 0.606 0.369 -0.163 0.594 0.478
CSNK1G1 1 -1.760 3.030 -0.583 0.273
CREBBP 0 0.840 -0.950 -3.889 -1.071
RALA 0 -0.480 0.600 0.727 0.398
XPO1 0 -0.520 0.800 0.240 1.064 0.205 0.673 0.522
SIRT1 0 0.910 -0.910
EP300 0 -1.210 1.320 -1.089 -1.694 -0.723
RBL2 0 0.890 -0.800
IKBKB 0 0.400 0.610
ZFAND5 0 -0.460 -0.120
ZFAND5 0 0.950 -0.350
GADD45A 0 1.050 -0.170
CDK2 0 -0.040 -0.300 -0.578 -0.797
CDK2 0 -0.040 -0.300 -0.202 -0.884 -0.107 -0.097 -0.501
YWHAH 0 0.000 0.080 1.206 0.159
YWHAH 0 0.000 0.080 0.546 0.338 0.541
CSNK1G2 0 -0.520 0.560 -0.583 0.273
CCNB1 0 -0.410 -0.128 0.212 -0.166 -0.523
CSNK1D 0 0.340 -0.060 0.150 0.527
CSNK1D 0 0.340 -0.060
CSNK1D 0 0.340 -0.060 1.237 -0.682 -0.148
AKT1 0 -0.050 0.700
AKT1 0 0.860 -0.040
RALB 0 -0.960 2.060
SKP2 0 0.030 0.690
SKP2 0 0.030 0.690
CSNK1G3 0 -0.480 0.480 -0.583 0.273
FBXO32 0 -0.520 -0.190
YWHAZ 0 0.880 -0.450 0.433 1.494 -0.337 0.631 0.064
YWHAB 0 0.628 -0.543
YWHAB 0 0.507 0.271 0.503
CTNNB1 0 0.490 -0.230
CTNNB1 0 0.490 -0.230 -0.415 0.628 0.215
YWHAG 0 0.298 -0.025
YWHAG 0 1.488 0.233 0.098
SFN 0 0.890 0.120 -4.300
USP7 0 -0.600 0.590
USP7 0 -0.600 0.590 0.789 -0.077 0.319 -0.125 0.108
CHUK 0 -0.480
CSNK1E 0 -0.170 -0.440 0.150 0.527
CSNK1E 0 -0.170 -0.440 1.237 -0.682 -0.148

PTM Sites:

 Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
AKT1 Phosphorylation S124 0.252 0.311 _SGS(ph)PSDNSGAEEMEVSLAKPK_
AKT1 Phosphorylation S126 -0.241 _SGSPS(ph)DNSGAEEM(ox)EVSLAK_
AKT1 Ubiquitylation K301 0.988 _EGIK(gl)DGATMK_
CCNB1 Ubiquitylation K18 -0.455 _AK(gl)INMAGAK_
CCNB1 Ubiquitylation K36 -1.833 -2.301 _VPTAPAATSK(gl)PGLRPR_
CCNB1 Ubiquitylation K59 -0.659 _VSEQLQAK(gl)MPMK_
CCNB1 Ubiquitylation K288 0.578 _QMEMK(gl)ILR_
CDK2 Ubiquitylation K6 -0.130 -0.399 _(ac)MENFQK(gl)VEK_
CDK2 Ubiquitylation K6 0.011 -0.784 _(ac)M(ox)EDYTK(gl)IEK_
CDK2 Phosphorylation T14 0.429 _IGEGT(ph)YGVVYK_
CDK2 Phosphorylation Y15 0.697 0.743 _IGEGTY(ph)GVVYK_
CDK2 Ubiquitylation K20 0.272 _IGEGTYGVVYK(gl)AR_
CDK2 Ubiquitylation K20 -0.327 -0.270 _IGEGTYGVVYK(gl)GR_
CDK2 Ubiquitylation K24 0.366 _NK(gl)LTGEVVALKK_
CDK2 Ubiquitylation K33 0.033 _NKLTGEVVALK(gl)K_
CDK2 Ubiquitylation K33 0.736 0.239 _TTGQVVAMK(gl)K_
CDK2 Ubiquitylation K34 0.542 _LTGEVVALKK(gl)_
CDK2 Ubiquitylation K34 -0.306 _TTGQVVAMKK(gl)_
CDK2 Ubiquitylation K58 0.312 -0.262 _EISLLK(gl)ELR_
CDK2 Ubiquitylation K136 -0.468 _DLK(gl)PQNLLIDDK(gl)GTIK_
CDK2 Ubiquitylation K145 0.161 -0.954 _DLKPQNLLIDDK(gl)GTIK_
CDK2 Ubiquitylation K149 -0.038 _GTIK(gl)LADFGLAR_
CDK2 Ubiquitylation K251 -0.047 -1.236 _WK(gl)PGSLASHVK_
CDK2 Ubiquitylation K280 0.179 -1.210 _MLIYDPAK(gl)R_
CDK2 Ubiquitylation K298 -1.907 -2.380 _QDFSK(gl)VVPPLDEDGR_
CHUK Ubiquitylation K296 -1.637 _GGPVDLTLK(gl)QPR_
CREBBP Phosphorylation S2093 0.037 0.097 _SIS(ph)PSALQDLLR_
CSNK1A1 Ubiquitylation K8 -0.342 -0.408 _(ac)ASSSGSK(gl)AEFIVGGK_
CSNK1A1 Ubiquitylation K18 0.772 _AEFIVGGKYK(gl)_
CSNK1A1 Ubiquitylation K225 0.039 0.502 _TSLPWQGLK(gl)AATK_
CSNK1A1 Ubiquitylation K304 -0.489 0.015 _QK(gl)AAQQAASSSGQGQQAQTPTGK_
CSNK1D Ubiquitylation K43 -1.168 _LECVK(gl)TK_
CSNK1D Ubiquitylation K45 -1.168 _LECVK(gl)TK_
CSNK1D Ubiquitylation K140 -0.969 _DVKPDNFLMGLGK(gl)K_
CSNK1D Ubiquitylation K141 -0.969 -0.720 _DVKPDNFLMGLGKK(gl)_
CSNK1D Phosphorylation S350 -0.790 _LRGTQEVAPPTPLTPTS(ph)HTANTSPRPVSGM(ox)ER_
CSNK1D Phosphorylation S363 -0.662 -0.352 _IQPAGNTS(ph)PR_
CSNK1D Phosphorylation S382 -0.647 -0.568 _GAPVNIS(ph)SSDLTGR_
CSNK1D Phosphorylation S389 0.394 0.817 _GAPANVS(ph)SSDLTGR_
CSNK1E Ubiquitylation K43 -1.168 _LECVK(gl)TK_
CSNK1E Ubiquitylation K45 -1.168 _LECVK(gl)TK_
CSNK1E Ubiquitylation K140 -0.969 _DVKPDNFLMGLGK(gl)K_
CSNK1E Ubiquitylation K141 -0.969 -0.720 _DVKPDNFLMGLGKK(gl)_
CSNK1E Phosphorylation S363 -0.662 -0.352 _IQPAGNTS(ph)PR_
CSNK1E Phosphorylation S389 0.394 0.817 _GAPANVS(ph)SSDLTGR_
CSNK1G1 Ubiquitylation K48 -0.536 _K(gl)IGCGNFGELR_
CSNK1G1 Ubiquitylation K198 -0.394 _EYIDPETK(gl)K_
CSNK1G1 Ubiquitylation K199 -0.394 _EYIDPETK(gl)K_
CSNK1G1 Ubiquitylation K253 0.276 0.386 _GSLPWQGLK(gl)ADTLK_
CSNK1G2 Ubiquitylation K48 -0.536 _K(gl)IGCGNFGELR_
CSNK1G2 Ubiquitylation K198 -0.394 _EYIDPETK(gl)K_
CSNK1G2 Ubiquitylation K199 -0.394 _EYIDPETK(gl)K_
CSNK1G2 Ubiquitylation K253 0.276 0.386 _GSLPWQGLK(gl)ADTLK_
CSNK1G3 Ubiquitylation K48 -0.536 _K(gl)IGCGNFGELR_
CSNK1G3 Ubiquitylation K198 -0.394 _EYIDPETK(gl)K_
CSNK1G3 Ubiquitylation K199 -0.394 _EYIDPETK(gl)K_
CSNK1G3 Ubiquitylation K253 0.276 0.386 _GSLPWQGLK(gl)ADTLK_
CTNNB1 Ubiquitylation K158 -1.265 _AIPELTK(gl)LLNDEDQVVVNK_
CTNNB1 Ubiquitylation K180 -0.546 -0.636 _AAVM(ox)VHQLSK(gl)K_
CTNNB1 Ubiquitylation K181 -0.717 -0.729 _AAVMVHQLSKK(gl)_
CTNNB1 Phosphorylation S191 -0.024 0.129 _S(ph)PQMVSAIVR_
CTNNB1 Ubiquitylation K435 -0.350 _NK(gl)MM(ox)VCQVGGIEALVR_
CTNNB1 Ubiquitylation K496 -1.262 _LHYGLPVVVK(gl)_
CTNNB1 Phosphorylation S552 1.233 1.224 _RTS(ph)MGGTQQQFVEGVR_
CTNNB1 Phosphorylation T556 1.275 0.995 _RTSM(ox)GGT(ph)QQQFVEGVR_
CTNNB1 Ubiquitylation K671 -0.941 -0.934 _MSEDKPQDYK(gl)K_
EP300 Phosphorylation S1038 -0.672 -0.349 _TEIKEEEDQPSTSATQSS(ph)PAPGQSK_
EP300 Phosphorylation S1726 0.994 0.627 _LGLGLDDESNNQQAAATQS(ph)PGDSRR_
EP300 Phosphorylation S2328 -1.092 0.725 _PQSQPPHSSPS(ph)PR_
FBXO32 Ubiquitylation K17 -3.237 _SPGQNWVK(gl)TADGWK_
FBXO32 Ubiquitylation K29 -0.747 _FLDEK(gl)SGSFVSDLSSYCNK_
FBXO32 Ubiquitylation K88 -0.982 _WIYVHK(gl)GSTK_
FBXO32 Ubiquitylation K268 -0.401 _K(gl)LCQYHFSER_
FOXO3 Phosphorylation S12 -1.324 _(ac)AEAPASPAPLS(ph)PLEVELDPEFEPQSRPR_
FOXO3 Phosphorylation S253 2.510 _AVS(ph)MDNSNKYTK_
FOXO3 Phosphorylation S284 4.138 6.011 _AALQTAPESADDS(ph)PSQLSK_
FOXO3 Phosphorylation S421 1.295 _GS(ph)GLGSPTSSFNSTVFGPSSLNSLR_
FOXO3 Phosphorylation S425 1.471 _GSGLGS(ph)PTSSFNSTVFGPSSLNSLR_
GADD45A Ubiquitylation K12 -0.515 0.281 _TLEEFSAGEQK(gl)TER_
GADD45A Ubiquitylation K29 0.092 _VGDALEEVLSK(gl)ALSQR_
IKBKB Ubiquitylation K106 0.253 _K(gl)YLNQFENCCGLR_
IKBKB Phosphorylation S672 0.670 0.244 _GPVSGS(ph)PDSMNASR_
KAT2B Phosphorylation S117 2.088 _NPNPS(ph)PTPPR_
MAPK9 Phosphorylation Y185 3.533 _TACTNFMMTPY(ph)VVTR_
PLK1 Ubiquitylation K358 -2.258 _EK(gl)EEPVVR_
PLK1 Ubiquitylation K574 1.656 _LSLLEEYGCCK(gl)ELASR_
RALA Ubiquitylation K7 0.700 _(ac)AANKPK(gl)GQNSLALHK_
RALA Ubiquitylation K134 0.656 -0.585 _SDLEDK(gl)RQVSVEEAK_
RALA Ubiquitylation K143 -0.388 _QVSVEEAK(gl)NR_
RALB Ubiquitylation K29 0.645 _SK(gl)GQSSLALHK_
RAN Ubiquitylation K23 0.056 _LVLVGDGGTGK(gl)TTFVK_
RAN Ubiquitylation K37 0.841 _HLTGEFEK(gl)K_
RAN Ubiquitylation K60 -0.488 0.477 _GPIK(gl)FNVWDTAGQEK_
RAN Ubiquitylation K71 1.279 _FNVWDTAGQEK(gl)FGGLR_
RAN Ubiquitylation K116 -0.044 1.823 _VTYK(gl)NVPNWHR_
RAN Ubiquitylation K140 -0.020 0.586 _VCENIPIVLCGNK(gl)VDIK_
RAN Ubiquitylation K144 0.131 0.529 _VCENIPIVLCGNKVDIK(gl)DR_
RAN Ubiquitylation K147 0.000 _VCENIPIVLCGNKVDIKDRK(gl)_
RAN Ubiquitylation K151 1.342 0.712 _AK(gl)SIVFHR_
RAN Ubiquitylation K158 0.185 0.370 _K(gl)KNLQYYDISAK_
RAN Ubiquitylation K159 0.246 0.274 _K(gl)NLQYYDISAK_
RAN Ubiquitylation K176 1.593 _SNYNFEK(gl)PFLWLAR_
RBL2 Phosphorylation S639 0.520 _ADEICIAGS(ph)PLTPR_
RBL2 Phosphorylation S662 0.551 0.137 _SITS(ph)PTTLYDR_
RBL2 Phosphorylation S981 -1.828 _SSSTLPVPQPS(ph)SAPPT(ph)PTR_
RBL2 Phosphorylation S982 -2.152 _SSSTLPVPQPSS(ph)APPT(ph)PTR_
RBL2 Phosphorylation T986 -1.219 -1.828 _SSSTLPVPQPSS(ph)APPT(ph)PTR_
RBL2 Phosphorylation S1078 0.241 0.286 _IFYYFS(ph)NSPSK_
RBL2 Phosphorylation S1080 -0.327 -0.297 _IFYYFSNS(ph)PSK_
RBL2 Phosphorylation S1112 -0.598 -0.843 _RGILLEDGSES(ph)PAKR_
SFN Ubiquitylation K11 0.561 0.388 _AK(gl)LAEQAER_
SFN Ubiquitylation K49 -0.093 0.337 _NLLSVAYK(gl)_
SIRT1 Phosphorylation S14 -0.369 -0.246 _(ac)ADEAALALQPGGS(ph)PSAAGADR_
SIRT1 Phosphorylation S16 -0.306 -1.665 _(ac)ADEAALALQPGGS(ph)PS(ph)AAGADREAASSPAGEPLR_
SIRT1 Phosphorylation S26 -1.047 -0.245 _EAAS(ph)SPAGEPLR_
SIRT1 Phosphorylation S27 0.351 -0.363 _EAASS(ph)PAGEPLR_
SIRT1 Phosphorylation S47 -0.574 -0.607 _S(ph)PGEPGGAAPER_
SIRT1 Ubiquitylation K238 -1.641 _RK(gl)DINTIEDAVK_
SIRT1 Ubiquitylation K499 -2.138 -0.204 _LGGEYAK(gl)LCCNPVK_
SIRT1 Ubiquitylation K578 -2.782 _GCMEEK(gl)PQEVQTSR_
SIRT1 Ubiquitylation K601 -3.051 _NVESIAEQMENPDLK(gl)NVGSSTGEK_
SKP2 Phosphorylation S8 -1.062 _SNLGHPES(ph)PPRK_
SKP2 Phosphorylation S64 -1.144 -1.189 _EEPDSENIPQELLSNLGHPES(ph)PPR_
SKP2 Phosphorylation S75 0.512 0.657 _SKGS(ph)DKDFVIVR_
SKP2 Ubiquitylation K228 -0.475 _LSDPIVNTLAK(gl)NSNLVR_
SKP2 Ubiquitylation K420 -1.178 _LTLQK(gl)PSCL_
USP7 Phosphorylation S18 -0.616 -0.581 _AGEQQLS(ph)EPEDM(ox)EM(ox)EAGDTDDPPR_
USP7 Ubiquitylation K158 -0.447 0.111 _IINYRDDEK(gl)SFSR_
USP7 Ubiquitylation K264 -1.350 _AVYMMPTEGDDSSK(gl)SVPLALQR_
USP7 Ubiquitylation K430 0.500 _FMYDPQTDQNIK(gl)INDR_
USP7 Ubiquitylation K605 1.273 _YTVFK(gl)VLK_
USP7 Ubiquitylation K834 -0.068 0.064 _MNYFQVAK(gl)TVAQR_
USP7 Ubiquitylation K879 -0.271 _DLLQFFK(gl)PR_
USP7 Ubiquitylation K892 0.402 0.347 _KLYYQQLK(gl)MK_
USP7 Ubiquitylation K894 0.380 _MK(gl)ITDFENRR_
USP7 Ubiquitylation K944 0.512 0.702 _KAVELGEK(gl)ASGK_
USP7 Ubiquitylation K1106 0.275 0.509 _YTYLEK(gl)AIK_
XPO1 Phosphorylation S391 -0.074 0.083 _ESPFSTSAS(ph)PLLSGSQHFDVPPR_
XPO1 Ubiquitylation K455 0.519 0.708 _DTDSINLYK(gl)NM(ox)R_
XPO1 Ubiquitylation K531 0.402 _DLLGLCEQK(gl)R_
XPO1 Ubiquitylation K680 -0.376 _NVDILK(gl)DPETVK_
XPO1 Ubiquitylation K693 0.285 0.582 _QLGSILK(gl)TNVR_
XPO1 Ubiquitylation K700 -0.104 _ACK(gl)AVGHPFVIQLGR_
YWHAB Ubiquitylation K11 1.057 1.322 _(ac)TMDKSELVQK(gl)AK_
YWHAB Ubiquitylation K13 0.060 0.388 _AK(gl)LAEQAER_
YWHAB Ubiquitylation K70 0.558 -0.175 _VISSIEQK(gl)TER_
YWHAB Ubiquitylation K140 0.531 _YLSEVASGDNK(gl)QTTVSNSQQAYQEAFEISKK_
YWHAB Ubiquitylation K159 0.300 _QTTVSNSQQAYQEAFEISK(gl)K_
YWHAB Ubiquitylation K160 -0.439 -0.371 _K(gl)EMQPTHPIR_
YWHAE Ubiquitylation K38 0.710 1.822 _YDEMVESMK(gl)K_
YWHAE Ubiquitylation K39 1.734 _YDEMVESMKK(gl)_
YWHAE Ubiquitylation K60 0.554 1.732 _NLLSVAYK(gl)NVIGAR_
YWHAE Ubiquitylation K83 0.375 0.643 _IISSIEQKEENK(gl)GGEDKLK_
YWHAE Ubiquitylation K90 1.103 _GGEDKLK(gl)MIR_
YWHAE Ubiquitylation K116 -0.289 _LICCDILDVLDK(gl)HLIPAANTGESK_
YWHAE Ubiquitylation K133 0.653 1.264 _VFYYK(gl)M(ox)K_
YWHAE Ubiquitylation K152 0.031 0.601 _K(gl)EAAENSLVAYK_
YWHAE Phosphorylation S210 0.534 0.506 _AAFDDAIAELDTLS(ph)EESYK_
YWHAE Phosphorylation S213 0.541 _AAFDDAIAELDTLSEES(ph)YK_
YWHAG Ubiquitylation K10 1.000 1.070 _VDREQLVQK(gl)AR_
YWHAG Ubiquitylation K69 0.708 1.242 _VISSIEQK(gl)TSADGNEK_
YWHAG Ubiquitylation K120 1.386 _NCSETQYESK(gl)VFYLK_
YWHAG Ubiquitylation K125 0.512 0.946 _VFYLK(gl)MK_
YWHAG Ubiquitylation K142 0.456 0.610 _YLAEVATGEK(gl)R_
YWHAH Ubiquitylation K143 0.540 _YLAEVASGEKK(gl)_
YWHAQ Ubiquitylation K3 0.827 _(ac)MEK(gl)TELIQK_
YWHAQ Ubiquitylation K9 0.588 0.253 _(ac)MEKTELIQK(gl)AK_
YWHAQ Ubiquitylation K11 0.561 0.388 _AK(gl)LAEQAER_
YWHAQ Ubiquitylation K27 -0.849 _YDDMATCMK(gl)AVTEQGAELSNEER_
YWHAQ Ubiquitylation K49 0.260 0.469 _NLLSVAYK(gl)NVVGGR_
YWHAQ Ubiquitylation K68 0.288 _VISSIEQK(gl)TDTSDKK_
YWHAQ Ubiquitylation K74 0.305 _TDTSDK(gl)KLQLIK_
YWHAQ Ubiquitylation K75 0.253 _TDTSDKK(gl)LQLIK_
YWHAQ Ubiquitylation K80 0.655 1.500 _LQLIK(gl)DYR_
YWHAQ Ubiquitylation K85 0.110 _EK(gl)VESELR_
YWHAQ Ubiquitylation K120 0.512 0.946 _VFYLK(gl)MK_
YWHAQ Ubiquitylation K122 0.426 0.859 _MK(gl)GDYFR_
YWHAQ Ubiquitylation K158 -0.439 -0.371 _K(gl)EMQPTHPIR_
YWHAZ Ubiquitylation K3 0.268 0.388 _(ac)MDK(gl)NELVQK_
YWHAZ Ubiquitylation K9 0.917 0.954 _(ac)MDKNELVQK(gl)AK_
YWHAZ Ubiquitylation K11 0.016 0.388 _AK(gl)LAEQAERYDDMAACMK_
YWHAZ Ubiquitylation K49 0.656 1.019 _NLLSVAYK(gl)NVVGAR_
YWHAZ Ubiquitylation K68 0.504 _VVSSIEQK(gl)TEGAEK_
YWHAZ Ubiquitylation K74 0.762 _VVSSIEQKTEGAEK(gl)K_
YWHAZ Ubiquitylation K85 -0.089 _EK(gl)IETELR_
YWHAZ Ubiquitylation K122 0.498 0.837 _MK(gl)GDYYR_
YWHAZ Ubiquitylation K138 0.560 1.003 _YLAEVAAGDDK(gl)K_
YWHAZ Ubiquitylation K139 0.551 1.003 _YLAEVAAGDDKK(gl)_
YWHAZ Ubiquitylation K166 -0.439 -0.371 _K(gl)EMQPTHPIR_
ZFAND5 Phosphorylation S48 -1.392 -1.513 _MS(ph)PMGTASGSNSPTSDSASVQR_
ZFAND5 Phosphorylation S58 0.737 _MS(ph)PMGTASGSNS(ph)PTSDSASVQR_
ZFAND5 Phosphorylation S61 -3.025 _M(ox)S(ph)PMGTASGSNSPTS(ph)DSASVQR_
ZFAND5 Ubiquitylation K86 -0.451 0.412 _ADTSLNNCEGAAGSTSEK(gl)SR_


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