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Query: YWHAG

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
YWHAG 0 4.478 0.298 -0.025
YWHAG 0 4.478 1.488 0.233 0.098

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
YWHAG Ubiquitylation K120 1.386 _NCSETQYESK(gl)VFYLK_
YWHAG Ubiquitylation K69 0.708 1.242 _VISSIEQK(gl)TSADGNEK_
YWHAG Ubiquitylation K10 1.000 1.070 _VDREQLVQK(gl)AR_
YWHAG Ubiquitylation K125 0.512 0.946 _VFYLK(gl)MK_
YWHAG Ubiquitylation K142 0.456 0.610 _YLAEVATGEK(gl)R_

Background Information for YWHAG:


Pubmed-YWHAG »
Uniprot-YWHAG »
Biogrid-YWHAG »
ProteomicsDB-YWHAG »

Tumorportal-YWHAG »
COSMIC-YWHAG »
GenomeRNAi-YWHAG »
Genecards-YWHAG


Protein-protein Interactions for YWHAG
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CDC25B Cat. description Hein, Mann, Cell 2015
Category members IP bait CENPE Cat. description Hein, Mann, Cell 2015
Category members IP bait KDR Cat. description Hein, Mann, Cell 2015
Category members IP bait KIF23 Cat. description Hein, Mann, Cell 2015
Category members IP bait MAP3K2 Cat. description Hein, Mann, Cell 2015
Category members IP bait RACGAP1 Cat. description Hein, Mann, Cell 2015
Category members IP bait RBM7 Cat. description Hein, Mann, Cell 2015
Category members IP bait WDR62 Cat. description Hein, Mann, Cell 2015
Category members IP bait YAP1 Cat. description Hein, Mann, Cell 2015
Category members IP bait YWHAH Cat. description Hein, Mann, Cell 2015
Category members IP bait YWHAZ Cat. description Hein, Mann, Cell 2015
Category members IP bait ANKRD55 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait BRAF Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C22orf33 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CDCA7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CGN Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CRTC2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait EPB41L2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait EPB49 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FAM163A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FAM189A2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FAM53C Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait KIAA0748 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait KIAA0930 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NKD2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PAK6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PLEKHG5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PRICKLE3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RAB11FIP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RALGPS2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RASSF2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait REEP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RIN1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SAMD4A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SAMD4B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SFN Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SMTNL2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SNX24 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SPATA13 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SSH1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TFEB Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNF397 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in YWHAG
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members 14/03/2003 IPR000308 1.96
Category members 14-3-3_domain IPR023410 1.96


Protein complexes (CORUM database) featuring YWHAG
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 5199 Kinase maturation complex 1 Database 3.38
Category members Corum 5919 BRAF-RAF1-14-3-3 complex Database 1.97


Categories featuring YWHAG
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members Pathway Pathway_320 REACTOME_CELL_CYCLE 0 11.08
Category members GO Category GO:0000278 mitotic cell cycle Database 10.63
Category members Pathway Pathway_317 REACTOME_CELL_CYCLE_MITOTIC 0 4.82
Category members Pathway Pathway_223 KEGG_OOCYTE_MEIOSIS 0 2.71
Category members Pathway Pathway_934 PID_PI3KCI_AKT_PATHWAY 0 2.5
Category members Pathway Pathway_866 KEGG_CELL_CYCLE 0 2.13
Category members GO Category GO:0006915 apoptotic process Database 2.12
Category members Pathway Pathway_724 PID_MTOR_4PATHWAY 0 2
Category members Pathway Pathway_579 PID_ERBB1_DOWNSTREAM_PATHWAY 0 1.97
Category members GO Category GO:0019904 protein domain specific binding Database 1.85
Category members Pathway Pathway_636 PID_PI3K_PLC_TRK_PATHWAY 0 1.85
Category members Pathway Pathway_455 PID_INSULIN_GLUCOSE_PATHWAY 0 1.7
Category members Pathway Pathway_1023 PID_NFAT_3PATHWAY 0 1.46
Category members GO Category GO:0070062 extracellular vesicular exosome Database 1.36
Category members Pathway Pathway_561 PID_PDGFRB_PATHWAY 0 1.18
Category members Pathway Pathway_118 PID_FOXO_PATHWAY 0 0.97
Category members Pathway Pathway_529 KEGG_NEUROTROPHIN_SIGNALING_PATHWAY 0 0.75
Category members GO Category GO:0032869 cellular response to insulin stimulus Database 0.63
Category members Pathway Pathway_509 SIG_INSULIN_RECEPTOR_PATHWAY_IN_CARDIAC_MYOCYTES 0 0.62
Category members GO Category GO:0030659 cytoplasmic vesicle membrane Database 0.62
Category members Pathway Pathway_123 BIOCARTA_CHREBP2_PATHWAY 0 0.61
Category members Pathway Pathway_1142 PID_LKB1_PATHWAY 0 0.6
Category members Pathway Pathway_199 PID_BETA_CATENIN_NUC_PATHWAY 0 0.53
Category members Pathway Pathway_727 REACTOME_MITOTIC_G2_G2_M_PHASES 0 0.46
Category members Pathway Pathway_444 PID_P38_MK2_PATHWAY 0 0.42
Category members Pathway Pathway_728 REACTOME_RECRUITMENT_OF_MITOTIC_CENTROSOME_PROTEINS_AND_COMPLEXES 0 0.4
Category members Pathway Pathway_730 REACTOME_LOSS_OF_NLP_FROM_MITOTIC_CENTROSOMES 0 0.33
Category members GO Category GO:0000086 G2/M transition of mitotic cell cycle Database 0.33
Category members Pathway Pathway_408 ST_PHOSPHOINOSITIDE_3_KINASE_PATHWAY 0 0.32
Category members GO Category GO:0006605 protein targeting Database 0.29
Category members Pathway Pathway_165 SIG_PIP3_SIGNALING_IN_CARDIAC_MYOCTES 0 0.18
Category members GO Category GO:0008426 protein kinase C inhibitor activity Database 0.15
Category members GO Category GO:0048167 regulation of synaptic plasticity Database 0.14
Category members Pathway Pathway_626 PID_A6B1_A6B4_INTEGRIN_PATHWAY 0 0.09
Category members GO Category GO:0005080 protein kinase C binding Database 0.04
Category members Pathway Pathway_550 PID_IL3_PATHWAY 0 0
Category members GO Category GO:0005159 insulin-like growth factor receptor binding Database 0
Category members GO Category GO:0006469 negative regulation of protein kinase activity Database 0
Category members GO Category GO:0009966 regulation of signal transduction Database 0
Category members GO Category GO:0030971 receptor tyrosine kinase binding Database 0
Category members GO Category GO:0031988 membrane-bounded vesicle Database 0
Category members GO Category GO:0045664 regulation of neuron differentiation Database 0


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