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PID_P38_MK2_PATHWAY
(Pathway_444)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
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Protein Results:

Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
MAPK14 2 -0.160 -0.350
TSC2 1 0.810 -0.710
TSC2 1 0.810 -0.710 -0.715
YWHAE 1 0.440 -0.380 1.095 -0.160
YWHAE 1 0.440 -0.380 1.129 0.621 0.321
RAF1 1 2.020 -1.230
YWHAQ 1 -0.260 0.670 0.606 0.369 -0.163 0.594 0.478
TCF3 0 0.270 -0.020
CDC25B 0 -0.180 0.320
HSPB1 0 0.710 -0.660 -0.632
SRF 0 0.670 -1.020
CREB1 0 1.080 -0.800 -1.027
YWHAH 0 0.000 0.080 1.206 0.159
YWHAH 0 0.000 0.080 0.546 0.338 0.541
YWHAZ 0 0.880 -0.450 0.433 1.494 -0.337 0.631 0.064
YWHAB 0 0.628 -0.543
YWHAB 0 0.507 0.271 0.503
YWHAG 0 0.298 -0.025
YWHAG 0 1.488 0.233 0.098
SFN 0 0.890 0.120 -4.300

PTM Sites:

Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
CDC25B Phosphorylation S117 -0.601 _EAFAQRPS(ph)SAPDLMCLSPDR_
CDC25B Phosphorylation S118 -0.832 _EAFAQRPS(ph)SAPDLMCLSPDR_
CDC25B Phosphorylation S241 -2.288 -1.005 _S(ph)VTPPEEQQEAEEPK_
CDC25B Phosphorylation T243 -1.445 _SVT(ph)PPEEQQEAEEPK_
CDC25B Phosphorylation S261 0.275 _S(ph)KSLCHDEIENLLDSDHR_
CDC25B Phosphorylation S263 0.184 _SKS(ph)LCHDEIENLLDSDHR_
CREB1 Phosphorylation S271 -0.979 -1.450 _TAPTSTIAPGVVM(ox)ASS(ph)PALPTQPAEEAAR_
CREB1 Ubiquitylation K333 1.343 _ALK(gl)DLYCHK_
HSPB1 Phosphorylation S82 1.036 0.723 _QLS(ph)SGVSEIR_
HSPB1 Ubiquitylation K198 -1.654 _AQLGGPEAAK(gl)SDETAAK_
MAPK14 Phosphorylation S2 3.221 3.623 _(ac)S(ph)QERPTFYR_
MAPK14 Phosphorylation T180 0.958 1.087 _HTDDEM(ox)T(ph)GYVATR_
MAPK14 Phosphorylation Y182 1.388 1.374 _HTDDEM(ox)TGY(ph)VATR_
MAPK14 Ubiquitylation K249 0.073 -1.380 _LVGTPGAELLKK(gl)_
RAF1 Phosphorylation S29 0.028 -0.571 _DAVFDGSSCIS(ph)PTIVQQFGYQR_
RAF1 Phosphorylation T31 0.028 -0.669 _DAVFDGSSCIS(ph)PTIVQQFGYQR_
RAF1 Phosphorylation S244 0.053 _YSTPHAFTFNTSS(ph)PSSEGSLSQR_
RAF1 Phosphorylation S259 -0.069 0.054 _STS(ph)TPNVHM(ox)VSTTLPVDSR_
RAF1 Phosphorylation S301 -0.651 _SHSESASPSALSSSPNNLS(ph)PTGWSQPK_
RAF1 Phosphorylation T303 -0.664 _SHSESASPSALSSSPNNLSPT(ph)GWSQPK_
RAF1 Phosphorylation S497 -0.449 _SRWS(ph)GSQQVEQPTGSVLWMAPEVIR_
RAF1 Phosphorylation S621 0.212 0.271 _SAS(ph)EPSLHR_
RAF1 Phosphorylation S642 -0.197 0.463 _AAHTEDINACTLTTS(ph)PR_
SFN Ubiquitylation K11 0.561 0.388 _AK(gl)LAEQAER_
SFN Ubiquitylation K49 -0.093 0.337 _NLLSVAYK(gl)_
SRF Phosphorylation S224 -0.512 -0.458 _ALIQTCLNSPDS(ph)PPR_
TCF3 Phosphorylation S328 0.865 0.756 _AGAPGALS(ph)PSYDGGLHGLQSK_
TSC2 Ubiquitylation K3 -1.397 _(ac)AK(gl)PTSKDSGLK_
TSC2 Ubiquitylation K14 -1.297 _DSGLKEK(gl)FK_
TSC2 Ubiquitylation K69 0.051 _MIGQICEVAK(gl)TK_
TSC2 Ubiquitylation K71 -0.157 _MIGQICEVAKTK(gl)_
TSC2 Ubiquitylation K258 -0.278 _ELCEPCWK(gl)LMR_
TSC2 Ubiquitylation K634 1.610 _LGLPNK(gl)DGVVR_
TSC2 Phosphorylation S950 -0.152 -0.529 _STS(ph)LNERPK_
TSC2 Phosphorylation S1064 -0.927 _SLLGLDSGELQSGPESSSS(ph)PGVHVR_
TSC2 Phosphorylation S1248 -0.604 _SNTDSAVVMEEGS(ph)PGEVPVLVEPPGLEDVEAALGMDRR_
TSC2 Phosphorylation S1329 -0.120 _S(ph)SSSPELQTLQDILGDPGDK_
TSC2 Phosphorylation S1331 -0.262 _SSS(ph)SPELQTLQDILGDPGDKADVGR_
TSC2 Phosphorylation S1332 -0.063 _SSSS(ph)PELQTLQDILGDPGDK_
TSC2 Phosphorylation S1355 0.174 0.351 _ADVGRLS(ph)PEVK_
TSC2 Phosphorylation S1362 0.859 _S(ph)QSGTLDGESAAWSASGEDSR_
TSC2 Phosphorylation S1364 0.522 0.550 _SQS(ph)GTLDGESAAWSASGEDSR_
TSC2 Phosphorylation T1366 0.137 _SQSGT(ph)LDGESAAWSASGEDSR_
TSC2 Phosphorylation S1396 0.498 _S(ph)PSGLRPR_
TSC2 Phosphorylation S1743 0.596 _RLISS(ph)VEDFTEFV_
YWHAB Ubiquitylation K11 1.057 1.322 _(ac)TMDKSELVQK(gl)AK_
YWHAB Ubiquitylation K13 0.060 0.388 _AK(gl)LAEQAER_
YWHAB Ubiquitylation K70 0.558 -0.175 _VISSIEQK(gl)TER_
YWHAB Ubiquitylation K140 0.531 _YLSEVASGDNK(gl)QTTVSNSQQAYQEAFEISKK_
YWHAB Ubiquitylation K159 0.300 _QTTVSNSQQAYQEAFEISK(gl)K_
YWHAB Ubiquitylation K160 -0.439 -0.371 _K(gl)EMQPTHPIR_
YWHAE Ubiquitylation K38 0.710 1.822 _YDEMVESMK(gl)K_
YWHAE Ubiquitylation K39 1.734 _YDEMVESMKK(gl)_
YWHAE Ubiquitylation K60 0.554 1.732 _NLLSVAYK(gl)NVIGAR_
YWHAE Ubiquitylation K83 0.375 0.643 _IISSIEQKEENK(gl)GGEDKLK_
YWHAE Ubiquitylation K90 1.103 _GGEDKLK(gl)MIR_
YWHAE Ubiquitylation K116 -0.289 _LICCDILDVLDK(gl)HLIPAANTGESK_
YWHAE Ubiquitylation K133 0.653 1.264 _VFYYK(gl)M(ox)K_
YWHAE Ubiquitylation K152 0.031 0.601 _K(gl)EAAENSLVAYK_
YWHAE Phosphorylation S210 0.534 0.506 _AAFDDAIAELDTLS(ph)EESYK_
YWHAE Phosphorylation S213 0.541 _AAFDDAIAELDTLSEES(ph)YK_
YWHAG Ubiquitylation K10 1.000 1.070 _VDREQLVQK(gl)AR_
YWHAG Ubiquitylation K69 0.708 1.242 _VISSIEQK(gl)TSADGNEK_
YWHAG Ubiquitylation K120 1.386 _NCSETQYESK(gl)VFYLK_
YWHAG Ubiquitylation K125 0.512 0.946 _VFYLK(gl)MK_
YWHAG Ubiquitylation K142 0.456 0.610 _YLAEVATGEK(gl)R_
YWHAH Ubiquitylation K143 0.540 _YLAEVASGEKK(gl)_
YWHAQ Ubiquitylation K3 0.827 _(ac)MEK(gl)TELIQK_
YWHAQ Ubiquitylation K9 0.588 0.253 _(ac)MEKTELIQK(gl)AK_
YWHAQ Ubiquitylation K11 0.561 0.388 _AK(gl)LAEQAER_
YWHAQ Ubiquitylation K27 -0.849 _YDDMATCMK(gl)AVTEQGAELSNEER_
YWHAQ Ubiquitylation K49 0.260 0.469 _NLLSVAYK(gl)NVVGGR_
YWHAQ Ubiquitylation K68 0.288 _VISSIEQK(gl)TDTSDKK_
YWHAQ Ubiquitylation K74 0.305 _TDTSDK(gl)KLQLIK_
YWHAQ Ubiquitylation K75 0.253 _TDTSDKK(gl)LQLIK_
YWHAQ Ubiquitylation K80 0.655 1.500 _LQLIK(gl)DYR_
YWHAQ Ubiquitylation K85 0.110 _EK(gl)VESELR_
YWHAQ Ubiquitylation K120 0.512 0.946 _VFYLK(gl)MK_
YWHAQ Ubiquitylation K122 0.426 0.859 _MK(gl)GDYFR_
YWHAQ Ubiquitylation K158 -0.439 -0.371 _K(gl)EMQPTHPIR_
YWHAZ Ubiquitylation K3 0.268 0.388 _(ac)MDK(gl)NELVQK_
YWHAZ Ubiquitylation K9 0.917 0.954 _(ac)MDKNELVQK(gl)AK_
YWHAZ Ubiquitylation K11 0.016 0.388 _AK(gl)LAEQAERYDDMAACMK_
YWHAZ Ubiquitylation K49 0.656 1.019 _NLLSVAYK(gl)NVVGAR_
YWHAZ Ubiquitylation K68 0.504 _VVSSIEQK(gl)TEGAEK_
YWHAZ Ubiquitylation K74 0.762 _VVSSIEQKTEGAEK(gl)K_
YWHAZ Ubiquitylation K85 -0.089 _EK(gl)IETELR_
YWHAZ Ubiquitylation K122 0.498 0.837 _MK(gl)GDYYR_
YWHAZ Ubiquitylation K138 0.560 1.003 _YLAEVAAGDDK(gl)K_
YWHAZ Ubiquitylation K139 0.551 1.003 _YLAEVAAGDDKK(gl)_
YWHAZ Ubiquitylation K166 -0.439 -0.371 _K(gl)EMQPTHPIR_


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