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Query: YWHAH

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
YWHAH 0 3.410 0.000 0.080 1.206 0.159
YWHAH 0 3.410 0.000 0.080 0.546 0.338 0.541

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
YWHAH Ubiquitylation K143 0.540 _YLAEVASGEKK(gl)_

Background Information for YWHAH:


Pubmed-YWHAH »
Uniprot-YWHAH »
Biogrid-YWHAH »
ProteomicsDB-YWHAH »

Tumorportal-YWHAH »
COSMIC-YWHAH »
GenomeRNAi-YWHAH »
Genecards-YWHAH


Protein-protein Interactions for YWHAH
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ACTR1B Cat. description Hein, Mann, Cell 2015
Category members IP bait CDC25B Cat. description Hein, Mann, Cell 2015
Category members IP bait CENPE Cat. description Hein, Mann, Cell 2015
Category members IP bait CENPJ;DKFZp667E025 Cat. description Hein, Mann, Cell 2015
Category members IP bait HAUS1 Cat. description Hein, Mann, Cell 2015
Category members IP bait KIF23 Cat. description Hein, Mann, Cell 2015
Category members IP bait PARD6B Cat. description Hein, Mann, Cell 2015
Category members IP bait RAF1 Cat. description Hein, Mann, Cell 2015
Category members IP bait RBM7 Cat. description Hein, Mann, Cell 2015
Category members IP bait WDR62 Cat. description Hein, Mann, Cell 2015
Category members IP bait YAP1 Cat. description Hein, Mann, Cell 2015
Category members IP bait YWHAH Cat. description Hein, Mann, Cell 2015
Category members IP bait YWHAZ Cat. description Hein, Mann, Cell 2015
Category members IP bait BRAF Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CDCA7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CGN Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait KIAA0748 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait KIAA0930 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PLEKHG5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PRICKLE3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RIN1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SAMD4A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SMTNL2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SPATA13 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in YWHAH
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members 14/03/2003 IPR000308 1.96
Category members 14-3-3_domain IPR023410 1.96


Protein complexes (CORUM database) featuring YWHAH
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 5199 Kinase maturation complex 1 Database 3.38
Category members Corum 5919 BRAF-RAF1-14-3-3 complex Database 1.97


Categories featuring YWHAH
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0003779 actin binding Database 5.41
Category members Pathway Pathway_223 KEGG_OOCYTE_MEIOSIS 0 2.71
Category members Pathway Pathway_934 PID_PI3KCI_AKT_PATHWAY 0 2.5
Category members GO Category GO:0006886 intracellular protein transport Database 2.48
Category members Pathway Pathway_866 KEGG_CELL_CYCLE 0 2.13
Category members GO Category GO:0006915 apoptotic process Database 2.12
Category members Pathway Pathway_724 PID_MTOR_4PATHWAY 0 2
Category members Pathway Pathway_579 PID_ERBB1_DOWNSTREAM_PATHWAY 0 1.97
Category members GO Category GO:0019904 protein domain specific binding Database 1.85
Category members Pathway Pathway_636 PID_PI3K_PLC_TRK_PATHWAY 0 1.85
Category members Pathway Pathway_455 PID_INSULIN_GLUCOSE_PATHWAY 0 1.7
Category members GO Category GO:0019899 enzyme binding Database 1.57
Category members Pathway Pathway_1023 PID_NFAT_3PATHWAY 0 1.46
Category members GO Category GO:0070062 extracellular vesicular exosome Database 1.36
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members Pathway Pathway_561 PID_PDGFRB_PATHWAY 0 1.18
Category members Pathway Pathway_118 PID_FOXO_PATHWAY 0 0.97
Category members Pathway Pathway_529 KEGG_NEUROTROPHIN_SIGNALING_PATHWAY 0 0.75
Category members GO Category GO:0014704 intercalated disc Database 0.64
Category members Pathway Pathway_509 SIG_INSULIN_RECEPTOR_PATHWAY_IN_CARDIAC_MYOCYTES 0 0.62
Category members GO Category GO:0030659 cytoplasmic vesicle membrane Database 0.62
Category members Pathway Pathway_123 BIOCARTA_CHREBP2_PATHWAY 0 0.61
Category members Pathway Pathway_1142 PID_LKB1_PATHWAY 0 0.6
Category members Pathway Pathway_199 PID_BETA_CATENIN_NUC_PATHWAY 0 0.53
Category members Pathway Pathway_542 BIOCARTA_AKT_PATHWAY 0 0.45
Category members Pathway Pathway_444 PID_P38_MK2_PATHWAY 0 0.42
Category members GO Category GO:0017080 sodium channel regulator activity Database 0.37
Category members Pathway Pathway_408 ST_PHOSPHOINOSITIDE_3_KINASE_PATHWAY 0 0.32
Category members Pathway Pathway_45 PID_REG_GR_PATHWAY 0 0.31
Category members GO Category GO:0045893 positive regulation of transcription, DNA-dependent Database 0.28
Category members GO Category GO:0046982 protein heterodimerization activity Database 0.28
Category members Pathway Pathway_982 BIOCARTA_G2_PATHWAY 0 0.24
Category members Pathway Pathway_165 SIG_PIP3_SIGNALING_IN_CARDIAC_MYOCTES 0 0.18
Category members GO Category GO:0048167 regulation of synaptic plasticity Database 0.14
Category members Pathway Pathway_626 PID_A6B1_A6B4_INTEGRIN_PATHWAY 0 0.09
Category members GO Category GO:0042921 glucocorticoid receptor signaling pathway Database 0.04
Category members GO Category GO:0044325 ion channel binding Database 0.03
Category members Pathway Pathway_1030 BIOCARTA_RB_PATHWAY 0 0
Category members Pathway Pathway_212 BIOCARTA_IGF1R_PATHWAY 0 0
Category members Pathway Pathway_250 BIOCARTA_BAD_PATHWAY 0 0
Category members Pathway Pathway_574 BIOCARTA_HDAC_PATHWAY 0 0
Category members Pathway Pathway_613 BIOCARTA_ACH_PATHWAY 0 0
Category members Pathway Pathway_938 BIOCARTA_PGC1A_PATHWAY 0 0
Category members GO Category GO:0002028 regulation of sodium ion transport Database 0
Category members GO Category GO:0005159 insulin-like growth factor receptor binding Database 0
Category members GO Category GO:0035259 glucocorticoid receptor binding Database 0
Category members GO Category GO:0045664 regulation of neuron differentiation Database 0
Category members GO Category GO:0050774 negative regulation of dendrite morphogenesis Database 0


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