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BIOCARTA_PGC1A_PATHWAY
(Pathway_938)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
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Protein Results:

Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
CAMK2G 2 -2.070 4.160
CAMK2G 2 -2.070 4.160
CAMK2G 2 -2.070 4.160 -0.654 0.073
CAMK2G 2 -2.070 4.160 0.559 1.698
CAMK2B 1 1.200 -0.790
CAMK2B 1 1.200 -0.790 -0.654 0.073
CAMK2B 1 1.200 -0.790 -0.619 0.544 0.125
CAMK2B 1 1.200 -0.790 0.559 1.698
CALM2 1 -0.690 0.700 1.911
CALM2 1 -0.690 0.700 0.877 -4.680
CALM3 1 -0.190 0.120 1.911
CALM3 1 -0.190 0.120 0.877 -4.680
CALM1 1 -0.440 0.360 1.911
CALM1 1 -0.440 0.360 0.877 -4.680
MEF2A 0 0.820 -0.530
MEF2A 0 0.820 -0.530
CAMK2A 0 -0.430 0.130 -0.654 0.073
CAMK2A 0 -0.430 0.130 -0.619 0.544 0.125
MEF2C 0 -0.980 1.550
MEF2C 0 -0.980 1.550
PPP3CB 0 -1.240 2.140 -0.298 1.130
PPP3CB 0 -1.240 2.140 0.923 0.537
HDAC5 0 -0.830 1.270
MEF2D 0 -0.080 -0.210
MEF2D 0 -0.080 -0.210
MEF2D 0 -0.080 -0.210
PPP3CC 0 -0.380 1.050 -0.298 1.130
PPP3CC 0 -0.380 1.050 0.923 0.537
YWHAH 0 0.000 0.080 1.206 0.159
YWHAH 0 0.000 0.080 0.546 0.338 0.541
CAMK1 0 1.160 -0.740
PPP3CA 0 1.550 -1.230 -0.298 1.130
PPP3CA 0 1.550 -1.230 0.923 0.537
CAMK2D 0 -0.260 0.500 -0.654 0.073
CAMK2D 0 -0.260 0.500 -0.619 0.544 0.125
CAMK2D 0 -0.260 0.500
CAMK4 0 0.780 -0.790
ESRRA 0 -0.770 0.700 0.047 0.181

PTM Sites:

Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
CALM1 Ubiquitylation K78 0.061 _DGDGTITTK(gl)ELGTVMR_
CALM1 Ubiquitylation K142 0.922 _VFDK(gl)DGNGYISAAELR_
CALM2 Ubiquitylation K78 0.061 _DGDGTITTK(gl)ELGTVMR_
CALM2 Ubiquitylation K142 0.922 _VFDK(gl)DGNGYISAAELR_
CALM3 Ubiquitylation K78 0.061 _DGDGTITTK(gl)ELGTVMR_
CALM3 Ubiquitylation K142 0.922 _VFDK(gl)DGNGYISAAELR_
CAMK1 Ubiquitylation K49 -0.158 _LVAIK(gl)CIAK_
CAMK2A Ubiquitylation K251 -0.437 _DLINK(gl)MLTINPAK_
CAMK2B Ubiquitylation K147 -1.064 _DLKPENLLLASK(gl)CK_
CAMK2B Ubiquitylation K251 -0.437 _DLINK(gl)MLTINPAK_
CAMK2D Ubiquitylation K251 -0.437 _DLINK(gl)MLTINPAK_
CAMK2D Phosphorylation S330 0.412 0.370 _KPDGVKES(ph)TESSNTTIEDEDVK_
CAMK2D Phosphorylation T331 -0.174 _KPDGVKES(ph)TESSNTTIEDEDVK_
CAMK2D Phosphorylation T336 0.615 0.376 _ESTESSNT(ph)TIEDEDVK_
CAMK2D Phosphorylation T337 0.450 _ESTESSNTT(ph)IEDEDVK_
CAMK2G Ubiquitylation K147 -1.064 _DLKPENLLLASK(gl)CK_
CAMK2G Ubiquitylation K251 -0.437 _DLINK(gl)MLTINPAK_
CAMK2G Phosphorylation S365 0.765 _GSTES(ph)CNTTTEDEDLK_
CAMK4 Phosphorylation S360 -0.256 0.086 _DPS(ph)PIQDGNEDMK_
HDAC5 Phosphorylation S265 -0.390 _RS(ph)SPLLR_
HDAC5 Phosphorylation S266 -0.821 -0.598 _RSS(ph)PLLR_
MEF2A Ubiquitylation K23 -0.140 _QVTFTK(gl)R_
MEF2A Phosphorylation S235 0.664 -0.092 _AS(ph)PNLIGATGANSLGK_
MEF2A Phosphorylation T253 -1.271 _VMPT(ph)KSPPPPGGGNLGMNSR_
MEF2A Phosphorylation S255 -1.235 _VMPTKS(ph)PPPPGGGNLGMNSR_
MEF2A Phosphorylation S408 -0.173 -0.049 _SEPIS(ph)PPRDR_
MEF2A Phosphorylation S494 -0.858 -1.232 _GDFHSPIVLGRPPNTEDRES(ph)PSVK_
MEF2C Ubiquitylation K23 -0.140 _QVTFTK(gl)R_
MEF2C Phosphorylation S240 0.008 0.302 _NS(ph)PGLLVSPGNLNK_
MEF2C Phosphorylation S406 0.272 0.338 _SEPVS(ph)PPRDR_
MEF2D Ubiquitylation K23 -0.140 _QVTFTK(gl)R_
MEF2D Phosphorylation S184 -1.118 -1.050 _VIPAKS(ph)PPPPTHSTQLGAPSR_
MEF2D Phosphorylation S185 0.259 -0.467 _LLS(ph)PQQPALQR_
MEF2D Phosphorylation S377 0.418 0.181 _SEPVS(ph)PSRER_
PPP3CA Ubiquitylation K32 -0.137 _LTAK(gl)EVFDNDGKPR_
PPP3CA Ubiquitylation K56 0.132 _VDVLK(gl)NHLVK_
PPP3CA Ubiquitylation K323 0.705 _AAVLK(gl)YENNVMNIR_
PPP3CA Ubiquitylation K405 0.078 _AIGK(gl)MAR_
PPP3CB Ubiquitylation K32 -0.137 _LTAK(gl)EVFDNDGKPR_
PPP3CB Ubiquitylation K56 0.132 _VDVLK(gl)NHLVK_
PPP3CB Ubiquitylation K323 0.705 _AAVLK(gl)YENNVMNIR_
PPP3CB Ubiquitylation K405 0.078 _AIGK(gl)MAR_
PPP3CC Ubiquitylation K32 -0.137 _LTAK(gl)EVFDNDGKPR_
PPP3CC Ubiquitylation K56 0.132 _VDVLK(gl)NHLVK_
PPP3CC Ubiquitylation K323 0.705 _AAVLK(gl)YENNVMNIR_
PPP3CC Ubiquitylation K405 0.078 _AIGK(gl)MAR_
YWHAH Ubiquitylation K143 0.540 _YLAEVASGEKK(gl)_


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