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Query: MEF2D

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
MEF2D 0 0.459 -0.080 -0.210

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
MEF2D Phosphorylation S377 0.418 0.181 _SEPVS(ph)PSRER_
MEF2D Ubiquitylation K23 -0.140 _QVTFTK(gl)R_
MEF2D Phosphorylation S185 0.259 -0.467 _LLS(ph)PQQPALQR_
MEF2D Phosphorylation S184 -1.118 -1.050 _VIPAKS(ph)PPPPTHSTQLGAPSR_

Background Information for MEF2D:


Pubmed-MEF2D »
Uniprot-MEF2D »
Biogrid-MEF2D »
ProteomicsDB-MEF2D »

Tumorportal-MEF2D »
COSMIC-MEF2D »
GenomeRNAi-MEF2D »
Genecards-MEF2D


Protein-protein Interactions for MEF2D
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait MAPK14 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MEF2B Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in MEF2D
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members TF_MADSbox IPR002100 0
Category members HJURP_C IPR022102 0


Protein complexes (CORUM database) featuring MEF2D
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring MEF2D
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0006915 apoptotic process Database 2.12
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members Pathway Pathway_1023 PID_NFAT_3PATHWAY 0 1.46
Category members GO Category GO:0006351 transcription, DNA-templated Database 1.07
Category members GO Category GO:0006366 transcription from RNA polymerase II promoter Database 0.96
Category members Pathway Pathway_157 REACTOME_CIRCADIAN_CLOCK 0 0.92
Category members GO Category GO:0003700 sequence-specific DNA binding transcription factor activity Database 0.63
Category members GO Category GO:0043231 intracellular membrane-bounded organelle Database 0.43
Category members Pathway Pathway_744 PID_HDAC_CLASSIII_PATHWAY 0 0.34
Category members Pathway Pathway_42 REACTOME_DEVELOPMENTAL_BIOLOGY 0 0.32
Category members GO Category GO:0045893 positive regulation of transcription, DNA-dependent Database 0.28
Category members GO Category GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding Database 0.21
Category members GO Category GO:0042826 histone deacetylase binding Database 0.16
Category members GO Category GO:0002062 chondrocyte differentiation Database 0.13
Category members GO Category GO:0045944 positive regulation of transcription from RNA polymerase II promoter Database 0.13
Category members GO Category GO:0001958 endochondral ossification Database 0.04
Category members Pathway Pathway_1000 BIOCARTA_MAPK_PATHWAY 0 0
Category members Pathway Pathway_1038 REACTOME_MYOGENESIS 0 0
Category members Pathway Pathway_1144 BIOCARTA_MEF2D_PATHWAY 0 0
Category members Pathway Pathway_570 BIOCARTA_ERK5_PATHWAY 0 0
Category members Pathway Pathway_574 BIOCARTA_HDAC_PATHWAY 0 0
Category members Pathway Pathway_723 BIOCARTA_P38MAPK_PATHWAY 0 0
Category members Pathway Pathway_938 BIOCARTA_PGC1A_PATHWAY 0 0
Category members Pathway Pathway_998 BIOCARTA_AT1R_PATHWAY 0 0
Category members GO Category GO:0000981 sequence-specific DNA binding RNA polymerase II transcription factor activity Database 0
Category members GO Category GO:0001649 osteoblast differentiation Database 0
Category members GO Category GO:0006355 regulation of transcription, DNA-dependent Database 0
Category members GO Category GO:0007399 nervous system development Database 0
Category members GO Category GO:0007512 adult heart development Database 0
Category members GO Category GO:0007517 muscle organ development Database 0
Category members GO Category GO:0033613 activating transcription factor binding Database 0
Category members GO Category GO:0035914 skeletal muscle cell differentiation Database 0
Category members GO Category GO:0046983 protein dimerization activity Database 0


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