bioLOGIC Data » bioLOGIC CategoryView » bioLOGIC VennView » Experimental Details »

bioLOGIC Data

bioLOGIC Data


Exact search


Query: HDAC5

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
W
[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
HDAC5 0 0.059 -0.830 1.270

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
HDAC5 Phosphorylation S265 -0.390 _RS(ph)SPLLR_
HDAC5 Phosphorylation S266 -0.821 -0.598 _RSS(ph)PLLR_

Background Information for HDAC5:


Pubmed-HDAC5 »
Uniprot-HDAC5 »
Biogrid-HDAC5 »
ProteomicsDB-HDAC5 »

Tumorportal-HDAC5 »
COSMIC-HDAC5 »
GenomeRNAi-HDAC5 »
Genecards-HDAC5


Protein-protein Interactions for HDAC5
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait LTBR Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in HDAC5
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members His_deacetylse IPR000286 0
Category members Histone_deAcase_II_euk IPR017320 0
Category members His_deacetylse_dom IPR023801 0
Category members Hist_deacetylase_Gln_rich_N IPR024643 0


Protein complexes (CORUM database) featuring HDAC5
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 1619 G protein complex (HDAC5, GNB1, GNG2) Database 0
Category members Corum 2 BCL6-HDAC5 complex Database 0


Categories featuring HDAC5
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005654 nucleoplasm Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0006325 chromatin organization Database 5.02
Category members GO Category GO:0006338 chromatin remodeling Database 4.95
Category members GO Category GO:0043234 protein complex Database 2.73
Category members GO Category GO:0045892 negative regulation of transcription, DNA-dependent Database 1.15
Category members Pathway Pathway_943 PID_HDAC_CLASSI_PATHWAY 0 1.08
Category members GO Category GO:0006351 transcription, DNA-templated Database 1.07
Category members GO Category GO:0042493 response to drug Database 0.66
Category members GO Category GO:0032869 cellular response to insulin stimulus Database 0.63
Category members GO Category GO:0006954 inflammatory response Database 0.49
Category members GO Category GO:0008134 transcription factor binding Database 0.37
Category members Pathway Pathway_117 REACTOME_SIGNALING_BY_NOTCH 0 0.33
Category members Pathway Pathway_1143 PID_HDAC_CLASSII_PATHWAY 0 0.3
Category members GO Category GO:0045668 negative regulation of osteoblast differentiation Database 0.29
Category members GO Category GO:0005794 Golgi apparatus Database 0.27
Category members Pathway Pathway_789 REACTOME_SIGNALING_BY_NOTCH1 0 0.22
Category members GO Category GO:0016568 chromatin modification Database 0.18
Category members Pathway Pathway_824 REACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION 0 0.14
Category members GO Category GO:0045944 positive regulation of transcription from RNA polymerase II promoter Database 0.13
Category members GO Category GO:0002076 osteoblast development Database 0.13
Category members GO Category GO:0033555 multicellular organismal response to stress Database 0.1
Category members GO Category GO:0007219 Notch signaling pathway Database 0.05
Category members GO Category GO:0043393 regulation of protein binding Database 0.04
Category members GO Category GO:0016604 nuclear body Database 0.04
Category members GO Category GO:0005080 protein kinase C binding Database 0.04
Category members GO Category GO:0000122 negative regulation of transcription from RNA polymerase II promoter Database 0.02
Category members GO Category GO:0044212 transcription regulatory region DNA binding Database 0
Category members Pathway Pathway_1097 BIOCARTA_ETS_PATHWAY 0 0
Category members Pathway Pathway_365 BIOCARTA_CARM_ER_PATHWAY 0 0
Category members Pathway Pathway_574 BIOCARTA_HDAC_PATHWAY 0 0
Category members Pathway Pathway_938 BIOCARTA_PGC1A_PATHWAY 0 0
Category members GO Category GO:0000118 histone deacetylase complex Database 0
Category members GO Category GO:0003714 transcription corepressor activity Database 0
Category members GO Category GO:0004407 histone deacetylase activity Database 0
Category members GO Category GO:0006342 chromatin silencing Database 0
Category members GO Category GO:0006950 response to stress Database 0
Category members GO Category GO:0007507 heart development Database 0
Category members GO Category GO:0010830 regulation of myotube differentiation Database 0
Category members GO Category GO:0010832 negative regulation of myotube differentiation Database 0
Category members GO Category GO:0016575 histone deacetylation Database 0
Category members GO Category GO:0030183 B cell differentiation Database 0
Category members GO Category GO:0032041 NAD-dependent histone deacetylase activity (H3-K14 specific) Database 0
Category members GO Category GO:0042113 B cell activation Database 0
Category members GO Category GO:0042220 response to cocaine Database 0
Category members GO Category GO:0046872 metal ion binding Database 0
Category members GO Category GO:0046969 NAD-dependent histone deacetylase activity (H3-K9 specific) Database 0
Category members GO Category GO:0046970 NAD-dependent histone deacetylase activity (H4-K16 specific) Database 0
Category members GO Category GO:0048742 regulation of skeletal muscle fiber development Database 0
Category members GO Category GO:0051091 positive regulation of sequence-specific DNA binding transcription factor activity Database 0
Category members GO Category GO:0051153 regulation of striated muscle cell differentiation Database 0
Category members GO Category GO:0070491 repressing transcription factor binding Database 0


.

© Copyright Svejstrup Laboratory 2015